An Open-label Extension Trial of HZNP-HZN-825-301 in Adult Participants With Diffuse Cutaneous Systemic Sclerosis (Diffuse Cutaneous SSc)
Public ClinicalTrials.gov record NCT05626751. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-label Extension Trial to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Patients With Diffuse Cutaneous Systemic Sclerosis
Study identification
- NCT ID
- NCT05626751
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Amgen
- Industry
- Enrollment
- 174 participants
Conditions and interventions
Interventions
- HZN-825 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 3, 2022
- Primary completion
- Feb 23, 2025
- Completion
- Feb 23, 2025
- Last update posted
- Jan 4, 2026
2022 – 2025
United States locations
- U.S. sites
- 11
- U.S. states
- 10
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis and Rheumatology Associates -4550 E Bell Rd | Phoenix | Arizona | 85032-9306 | — |
| UCLA Medical Center | Los Angeles | California | 90095-8344 | — |
| University of Miami Miller School of Medicine | Miami | Florida | 33136-1005 | — |
| IRIS Research and Development LLC | Plantation | Florida | 33324-2736 | — |
| DelRicht Clinical Research, LLC - Internal - Covington - PPDS | New Orleans | Louisiana | 70115-3584 | — |
| Boston University School Of Medicine | Boston | Massachusetts | 02118-2642 | — |
| Michigan Medicine University of Michigan | Ann Arbor | Michigan | 48109-5000 | — |
| Mayo Clinic - Cancer Center - Rochester - PPDS | Rochester | Minnesota | 55905 | — |
| Duke University Medical Center | Durham | North Carolina | 27710-3037 | — |
| Medical University of South Carolina (MUSC) - PPDS | Charleston | South Carolina | 29425-8900 | — |
| UT Physicians Rheumatology | Houston | Texas | 77030-5400 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 54 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05626751, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 4, 2026 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05626751 live on ClinicalTrials.gov.