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Active, not recruiting Phase 3 Interventional

Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab

ClinicalTrials.gov ID: NCT05626855

Public ClinicalTrials.gov record NCT05626855. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 7:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Multicenter, Extension Trial to Evaluate the Long-Term Safety and Efficacy of Apitegromab in Patients With Type 2 and Type 3 Spinal Muscular Atrophy Who Completed Previous Investigational Trials of Apitegromab

Study identification

NCT ID
NCT05626855
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Scholar Rock, Inc.
Industry
Enrollment
238 participants

Conditions and interventions

Eligibility (public fields only)

Age range
2 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 16, 2023
Primary completion
Oct 31, 2026
Completion
May 1, 2029
Last update posted
May 24, 2025

2023 – 2029

United States locations

U.S. sites
25
U.S. states
23
U.S. cities
25
Facility City State ZIP Site status
Phoenix Childrens Hospital Phoenix Arizona 85016
UCSD Altman Clinical and Translational Research La Jolla California 92037
Children's Hospital Los Angeles Los Angeles California 90027
Stanford Neuroscience Health Center Palo Alto California 94304
Children's Hospital Colorado Aurora Colorado 80045
Nemours Biomedical Research Orlando Florida 32827
Lurie Children's Hospital of Chicago Chicago Illinois 60611
University of Iowa Iowa City Iowa 52242
University of Kansas Medical Center Fairway Kansas 66205
Johns HopkinsHospital Baltimore Maryland 21287
Boston Children's Hospital Boston Massachusetts 02115
Helen DeVos Children's Hospital Grand Rapids Michigan 49503
Gillette Children's Specialty Healthcare Saint Paul Minnesota 55101
Washington University Medical Campus St Louis Missouri 63110
Columbia University Medical Center New York New York 10032
Wake Forest University School of Medicine Winston-Salem North Carolina 27157
Nationwide Children's Hospital Columbus Ohio 43215
Oregon Health & Science University Portland Oregon 97239
The Children's Hospital of Philadelphia Philadelphia Pennsylvania 19104
St. Jude Children's Research Hospital Memphis Tennessee 38105
University of Texas Southwestern - Pediatric Neurology Dallas Texas 75207
University of Utah Salt Lake City Utah 84112
Children's Specialty Group PLLC (Children's Hospital of The King's Daughters) Newport News Virginia 23606
Seattle Children's Hospital Seattle Washington 98115
University of Wisconsin Hospital Madison Wisconsin 53792

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 24 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05626855, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted May 24, 2025 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05626855 live on ClinicalTrials.gov.

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