A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome
Public ClinicalTrials.gov record NCT05627557. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, International, Multicenter, Randomised Open Label Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Patients With Childhood Onset Idiopathic Nephrotic Syndrome
Study identification
- NCT ID
- NCT05627557
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 85 participants
Conditions and interventions
Conditions
Interventions
- Obinutuzumab Drug
- MMF Drug
- Prednisone Drug
- Methylprednisolone Drug
- Acetaminophen/ Paracetamol Drug
- Diphenhydramine Hydrochloride Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 28, 2023
- Primary completion
- Sep 3, 2025
- Completion
- Sep 3, 2026
- Last update posted
- Dec 14, 2025
2023 – 2026
United States locations
- U.S. sites
- 10
- U.S. states
- 7
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Lucile Packard Children's Hospital - Stanford | Palo Alto | California | 94304-1601 | — |
| Memorial Healthcare System | Hollywood | Florida | 33021 | — |
| Nicklaus Children's Hospital | Miami | Florida | 33155-3009 | — |
| Nemours Children's Hospital | Orlando | Florida | 32827-7884 | — |
| University of South Florida | Tampa | Florida | 33606-3475 | — |
| Children's Healthcare of Atlanta Center for Advanced Pediatrics | Atlanta | Georgia | 30329-2309 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601-1915 | — |
| Levine Children's Hospital | Charlotte | North Carolina | 28203-5866 | — |
| University of Utah - Primary Children's Hospital - PPDS | Salt Lake City | Utah | 84113-1103 | — |
| University of Virginia Health System | Charlottesville | Virginia | 22903 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05627557, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05627557 live on ClinicalTrials.gov.