A Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
Public ClinicalTrials.gov record NCT05633355. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label, 52-week Study to Assess the Safety, Tolerability, and Efficacy of Rocatinlimab (AMG 451) in Adolescent Subjects Aged ≥ 12 to < 18 Years With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Orbit)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary objective of this study is to describe the safety and tolerability of rocatinlimab in adolescents with moderate-to-severe AD.
Study identification
- NCT ID
- NCT05633355
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 187 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2023 (Actual)
- Primary completion
- Jul 31, 2025 (Actual)
- Completion
- Jul 31, 2025 (Actual)
- Last update posted
- Jul 24, 2026
2023 – 2025
United States locations
- U.S. sites
- 22
- U.S. states
- 12
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Phoenix Childrens Hosptial | Phoenix | Arizona | 85016 | — |
| Medical Advancement Centers of Arizona | Tempe | Arizona | 85283 | — |
| Dermatology Trial Associates | Bryant | Arkansas | 72022 | — |
| Little Rock Allergy and Asthma Clinical Research Center | Little Rock | Arkansas | 72205 | — |
| University of California Irvine | Irvine | California | 92697 | — |
| University of California Los Angeles | Los Angeles | California | 90024 | — |
| Dermatology Research Associates | Los Angeles | California | 90045 | — |
| Manlio Dermatology | Kissimmee | Florida | 34741 | — |
| Palm Springs Community Health Center | Miami | Florida | 33014 | — |
| ARA Professionals Limited Liability Corporation | Miami | Florida | 33176 | — |
| Deluxe Health Care LLC | Miami Lakes | Florida | 33014 | — |
| Bluegrass Allergy Care | Lexington | Kentucky | 40509 | — |
| Windsor Dermatology dba Eczema Treatment Center of New Jersey | East Windsor | New Jersey | 08520 | — |
| Smart Medical Research Inc | Jackson Heights | New York | 11372 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| Auni Allergy | Findlay | Ohio | 45840 | — |
| Oregon Medical Research Center | Portland | Oregon | 97201 | — |
| DermDox Dermatology, LLC | Sugarloaf | Pennsylvania | 18249 | — |
| Driscoll Childrens Hospital | Corpus Christi | Texas | 78411 | — |
| Modern Research Associates | Dallas | Texas | 75231 | — |
| Center for Clinical Studies | Houston | Texas | 77004 | — |
| University of Utah MidValley Dermatology | Murray | Utah | 84107 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 55 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05633355, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 24, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05633355 live on ClinicalTrials.gov.