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Recruiting Phase 2 Interventional

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

ClinicalTrials.gov ID: NCT05633615

Public ClinicalTrials.gov record NCT05633615. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 9:13 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase II Trial of Consolidation Therapy Following CD19 CAR T-Cell Treatment for Relapsed/Refractory Diffuse Large B-Cell Lymphoma or Grade IIIB Follicular Lymphoma

Study identification

NCT ID
NCT05633615
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
SWOG Cancer Research Network
Network
Enrollment
396 participants

Conditions and interventions

Interventions

  • Axicabtagene Ciloleucel Biological
  • Biospecimen Collection Procedure
  • Computed Tomography Procedure
  • Cyclophosphamide Drug
  • Fludarabine Drug
  • Lisocabtagene Maraleucel Biological
  • Mosunetuzumab Biological
  • Patient Observation Other
  • Polatuzumab Vedotin Drug
  • Positron Emission Tomography Procedure
  • Tisagenlecleucel Biological

Biological · Procedure · Drug + 1 more

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 11, 2023
Primary completion
Jun 29, 2030
Completion
Jun 29, 2030
Last update posted
Feb 1, 2026

2023 – 2030

United States locations

U.S. sites
87
U.S. states
27
U.S. cities
70
Facility City State ZIP Site status
Banner University Medical Center - Tucson Tucson Arizona 85719 Recruiting
University of Arizona Cancer Center-North Campus Tucson Arizona 85719 Recruiting
Highlands Oncology Group - Fayetteville Fayetteville Arkansas 72703 Recruiting
University of Arkansas for Medical Sciences Little Rock Arkansas 72205 Recruiting
Highlands Oncology Group - Rogers Rogers Arkansas 72758 Recruiting
Highlands Oncology Group Springdale Arkansas 72762 Recruiting
UC Irvine Health Cancer Center-Newport Costa Mesa California 92627 Recruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care Irvine California 92612 Recruiting
UCI Health Laguna Hills Laguna Hills California 92653 Recruiting
UC Irvine Health/Chao Family Comprehensive Cancer Center Orange California 92868 Recruiting
UCSF Medical Center-Parnassus San Francisco California 94143 Recruiting
UF Health Cancer Institute - Gainesville Gainesville Florida 32610 Recruiting
Emory University Hospital/Winship Cancer Institute Atlanta Georgia 30322 Recruiting
Emory Saint Joseph's Hospital Atlanta Georgia 30342 Recruiting
Saint Luke's Cancer Institute - Boise Boise Idaho 83712 Recruiting
Saint Luke's Cancer Institute - Fruitland Fruitland Idaho 83619 Recruiting
Saint Luke's Cancer Institute - Meridian Meridian Idaho 83642 Recruiting
Saint Luke's Cancer Institute - Nampa Nampa Idaho 83687 Recruiting
Saint Luke's Cancer Institute - Twin Falls Twin Falls Idaho 83301 Recruiting
University of Illinois Chicago Illinois 60612 Recruiting
University of Chicago Comprehensive Cancer Center Chicago Illinois 60637 Recruiting
Loyola University Medical Center Maywood Illinois 60153 Suspended
University of Iowa/Holden Comprehensive Cancer Center Iowa City Iowa 52242 Recruiting
University of Kansas Cancer Center Kansas City Kansas 66160 Recruiting
University of Kansas Cancer Center-Overland Park Overland Park Kansas 66210 Recruiting
University of Kansas Hospital-Westwood Cancer Center Westwood Kansas 66205 Recruiting
The James Graham Brown Cancer Center at University of Louisville Louisville Kentucky 40202 Recruiting
UofL Health Medical Center Northeast Louisville Kentucky 40245 Recruiting
University of Maryland/Greenebaum Cancer Center Baltimore Maryland 21201 Recruiting
Johns Hopkins University/Sidney Kimmel Cancer Center Baltimore Maryland 21287 Recruiting
Bronson Battle Creek Battle Creek Michigan 49017 Recruiting
Wayne State University/Karmanos Cancer Institute Detroit Michigan 48201 Recruiting
Henry Ford Hospital Detroit Michigan 48202 Recruiting
Weisberg Cancer Treatment Center Farmington Hills Michigan 48334 Recruiting
Corewell Health Grand Rapids Hospitals - Butterworth Hospital Grand Rapids Michigan 49503 Recruiting
Trinity Health Grand Rapids Hospital Grand Rapids Michigan 49503 Recruiting
Bronson Methodist Hospital Kalamazoo Michigan 49007 Recruiting
West Michigan Cancer Center Kalamazoo Michigan 49007 Recruiting
Beacon Kalamazoo Cancer Center Kalamazoo Michigan 49009 Recruiting
Trinity Health Muskegon Hospital Muskegon Michigan 49444 Recruiting
Corewell Health Lakeland Hospitals - Niles Hospital Niles Michigan 49120 Recruiting
Cancer and Hematology Centers of Western Michigan - Norton Shores Norton Shores Michigan 49444 Recruiting
Corewell Health Reed City Hospital Reed City Michigan 49677 Recruiting
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center Saint Joseph Michigan 49085 Recruiting
Henry Ford Health Providence Southfield Hospital Southfield Michigan 48075 Active, not recruiting
Munson Medical Center Traverse City Michigan 49684 Recruiting
University of Michigan Health - West Wyoming Michigan 49519 Recruiting
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center Lebanon New Hampshire 03756 Recruiting
University of New Mexico Cancer Center Albuquerque New Mexico 87106 Recruiting
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center New York New York 10032 Recruiting
NYP/Weill Cornell Medical Center New York New York 10065 Suspended
University of Rochester Rochester New York 14642 Recruiting
Wilmot Cancer Institute at Webster Webster New York 14580 Recruiting
Carolinas Medical Center/Levine Cancer Institute Charlotte North Carolina 28203 Recruiting
Atrium Health Cabarrus/LCI-Concord Concord North Carolina 28025 Recruiting
Duke University Medical Center Durham North Carolina 27710 Suspended
Wake Forest University Health Sciences Winston-Salem North Carolina 27157 Recruiting
Sanford Broadway Medical Center Fargo North Dakota 58122 Recruiting
Sanford Roger Maris Cancer Center Fargo North Dakota 58122 Recruiting
Case Western Reserve University Cleveland Ohio 44106 Recruiting
University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104 Recruiting
Providence Newberg Medical Center Newberg Oregon 97132 Recruiting
Providence Willamette Falls Medical Center Oregon City Oregon 97045 Recruiting
Providence Portland Medical Center Portland Oregon 97213 Recruiting
Providence Saint Vincent Medical Center Portland Oregon 97225 Recruiting
Oregon Health and Science University Portland Oregon 97239 Recruiting
Geisinger Medical Center Danville Pennsylvania 17822 Recruiting
University of Pennsylvania/Abramson Cancer Center Philadelphia Pennsylvania 19104 Recruiting
Geisinger Wyoming Valley/Henry Cancer Center Wilkes-Barre Pennsylvania 18711 Recruiting
Prisma Health Cancer Institute - Spartanburg Boiling Springs South Carolina 29316 Recruiting
Medical University of South Carolina Charleston South Carolina 29425 Recruiting
Prisma Health Cancer Institute - Easley Easley South Carolina 29640 Recruiting
Prisma Health Cancer Institute - Butternut Greenville South Carolina 29605 Recruiting
Prisma Health Cancer Institute - Faris Greenville South Carolina 29605 Recruiting
Prisma Health Cancer Institute - Eastside Greenville South Carolina 29615 Recruiting
Prisma Health Cancer Institute - Greer Greer South Carolina 29650 Recruiting
Prisma Health Cancer Institute - Seneca Seneca South Carolina 29672 Recruiting
Baptist Memorial Hospital and Cancer Center-Memphis Memphis Tennessee 38120 Recruiting
University of Vermont Medical Center Burlington Vermont 05401 Recruiting
University of Vermont and State Agricultural College Burlington Vermont 05405 Recruiting
Dartmouth Cancer Center - North Saint Johnsbury Vermont 05819 Recruiting
VCU Massey Comprehensive Cancer Center Richmond Virginia 23298 Recruiting
Swedish Medical Center-First Hill Seattle Washington 98122 Recruiting
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center Madison Wisconsin 53718 Recruiting
University of Wisconsin Carbone Cancer Center - University Hospital Madison Wisconsin 53792 Recruiting
Medical College of Wisconsin Milwaukee Wisconsin 53226 Recruiting
Froedtert and MCW Moorland Reserve Health Center New Berlin Wisconsin 53151 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05633615, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 1, 2026 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05633615 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →