Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF
Public ClinicalTrials.gov record NCT05639556. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of the study is to examine multiple markers of anthropometrics, body composition, sarcopenia and frailty and compare them to dual energy X-ray absorptiometry (DXA) output, which is considered the current clinical gold-standard tool to measure body composition. The result of this study will provide detailed data regarding the nutrition and body composition within this Cystic Fibrosis population and also provide a baseline evaluation for use of these biomarkers in the future studies including evaluation of nutritional intervention. Further, the study will also include psychosocial and other patient-reported outcomes and medical contributors to understand their contributions to the nutritional failure in the adult advanced lung disease population. Finally, the study will evaluate both established and emerging nutritional and body composition parameters and link them to clinical outcomes in adults with CF across the spectrum of pulmonary function.
Study identification
- NCT ID
- NCT05639556
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 300 participants
Conditions and interventions
Conditions
Interventions
- BMI and lean mass index from DXA Diagnostic Test
- Anthropometric Measurements Diagnostic Test
- Hand-grip strength Diagnostic Test
- Six-minute walk Test Diagnostic Test
- Sit-to-Stand Test Diagnostic Test
- Short physical performance battery (SPPB) Diagnostic Test
- BIA Sub-study Diagnostic Test
- Accelerometry to assess physical activity Diagnostic Test
- Gastrointestinal (GI) and nutrition questionnaires: Other
- Psychosocial questionnaire: PHQ-8 Other
- Psychosocial questionnaire: GAD-7 Other
- Psychosocial questionnaire: The Treatment Self-Regulation Questionnaire (TSRQ) Other
- Psychosocial questionnaire: CF Fatalism Scale Other
- Psychosocial questionnaire: Body Esteem Scale for Adolescents and Adults (BESAA) Other
- 12-month Questionnaire Other
- Oral glucose tolerance testing (OGTT) Other
- Continuous glucose monitoring (CGM) Device
- Chest CT scans (When available within the past 6 months in medical records) Diagnostic Test
- Hologic Dual X-Ray Absorptiometry (DXA) Diagnostic Test
- Ultrasound Sub-study of assessment of appendage muscles using ultrasound Diagnostic Test
- Psychosocial questionnaire: Hunger Vital Sign questionnaire Diagnostic Test
- Respiratory symptom questionnaire: CRISS Other
- Spirometry Diagnostic Test
- Psychosocial questionnaire: Additional Health Questionnaire Other
- CF Management Questionnaire Other
- Food Frequency Questionnaire Other
Diagnostic Test · Other · Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 19, 2023
- Primary completion
- Nov 30, 2028
- Completion
- Nov 30, 2028
- Last update posted
- Mar 12, 2026
2023 – 2028
United States locations
- U.S. sites
- 23
- U.S. states
- 20
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences (UAMS) | Little Rock | Arkansas | 72205 | — |
| Emory | Atlanta | Georgia | 30324 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| University of Kentucky | Lexington | Kentucky | 40508 | — |
| Tulane University | New Orleans | Louisiana | 70112 | — |
| John Hopkins University | Baltimore | Maryland | 21287 | — |
| Massachusetts General Hospital (MGH) | Boston | Massachusetts | 02114 | — |
| Boston Children's Hospital and Brigham and Women's CF Center | Boston | Massachusetts | 02120 | — |
| University of Minnesota | Minneapolis | Minnesota | 55455 | — |
| Washington University School of Medicine (St. Louis) | St Louis | Missouri | 63110 | — |
| Rutgers Health | New Brunswick | New Jersey | 08901 | — |
| New York Medical College (NYMC) | Hawthorne | New York | 10532 | — |
| Northwell LIJ Adult Cystic Fibrosis Center | New Hyde Park | New York | 11040 | — |
| University of Cincinnati | Cincinnati | Ohio | 45220 | — |
| University Hospitals | Cleveland | Ohio | 44106 | — |
| University of Oklahoma Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15224 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Baylor University | Houston | Texas | 77030 | — |
| University of Virginia Cystic Fibrosis Center | Charlottesville | Virginia | 22908 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05639556, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 12, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05639556 live on ClinicalTrials.gov.