Study to Determine the Efficacy&Safety of ARV-1801(ACG-701) for the Treatment of Cystic Fibrosis Pulmonary Exacerbations
Public ClinicalTrials.gov record NCT05641298. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, DB, Placebo-controlled Study to Determine the Efficacy, Safety and PK Profile of ARV-1801 in Combination With Optimized Background Therapy for the Treatment of Pulmonary Exacerbations in Patients With Cystic Fibrosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will evaluate the efficacy and safety of an oral ARV-1801(ACG-701) plus optimized background therapy (OBT) compared to oral placebo plus OBT, each administered for 14 days, in the treatment of participants with Cystic Fibrosis-related pulmonary exacerbations (PEx).
Study identification
- NCT ID
- NCT05641298
- Recruitment status
- Withdrawn
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- Not listed
Conditions and interventions
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 10, 2023 (Actual)
- Primary completion
- Sep 2023 (Estimated)
- Completion
- Sep 2023 (Estimated)
- Last update posted
- Jul 19, 2023
2023
United States locations
- U.S. sites
- 25
- U.S. states
- 19
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Florida | Gainesville | Florida | 32610 | — |
| Central Florida Pulmonary Group | Orlando | Florida | 32803 | — |
| Nemours Children's Health - Pensacola | Pensacola | Florida | 32514 | — |
| Johns Hopkins All Children's Hospital | St. Petersburg | Florida | 33701 | — |
| Cystic Fibrosis Center of Chicago | Chicago | Illinois | 60093 | — |
| Cystic Fibrosis Center of Chicago | Northfield | Illinois | 60093 | — |
| Riley Hospital for Children | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| University Of Louisville | Louisville | Kentucky | 40202 | — |
| Maine Medical Center | Portland | Maine | 04102 | — |
| Johns Hopkins University | Baltimore | Maryland | 21287 | — |
| University of Michigan, Michigan Medicine | Ann Arbor | Michigan | 48109 | — |
| Washington University School of Medicine | St Louis | Missouri | 63114 | — |
| UNMC-Nebraska CF Pediatric Center | Omaha | Nebraska | 68114 | — |
| Gunnar H. Esiason Adult Cystic Fibrosis Center | Morristown | New Jersey | 07960 | — |
| New York Medical College | Hawthorne | New York | 10532 | — |
| University of Rochester Medical Center Strong Memorial | Rochester | New York | 14642 | — |
| Rainbow Babies and Children's Hospital/Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma | 73104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15224 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Cook Children's Health Care System | Fort Worth | Texas | 76104 | — |
| The University of Health Science Center at Tyler | Tyler | Texas | 75708 | — |
| Providence Medical Research Center | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05641298, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 19, 2023 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05641298 live on ClinicalTrials.gov.