A Study to Investigate Vamikibart in Participants With Uveitic Macular Edema
Public ClinicalTrials.gov record NCT05642312. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Investigate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Vamikibart Administered Intravitreally in Patients With Uveitic Macular Edema
Study identification
- NCT ID
- NCT05642312
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 245 participants
Conditions and interventions
Conditions
Interventions
- Vamikibart Drug
- Sham Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 8, 2023
- Primary completion
- Dec 8, 2024
- Completion
- Jul 8, 2025
- Last update posted
- Nov 20, 2025
2023 – 2025
United States locations
- U.S. sites
- 16
- U.S. states
- 14
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kaiser Permanente Southern California | Los Angeles | California | 90027 | — |
| Colorado Retina Associates, PC | Lakewood | Colorado | 80228 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711-1141 | — |
| Cumberland Valley Retina PC | Hagerstown | Maryland | 21740 | — |
| VitreoRetinal Surgery, PLLC. | Minneapolis | Minnesota | 55435 | — |
| Truhlsen Eye Institute | Omaha | Nebraska | 68106-5540 | — |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | — |
| Wake Forest Baptist Health Eye Centre | Winston-Salem | North Carolina | 27157 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| The Ohio State University Investigational Drug Services | Columbus | Ohio | 43212 | — |
| Oregon Health & Science Uni | Portland | Oregon | 97239 | — |
| Erie Retina Research | Erie | Pennsylvania | 16507-1429 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| Austin Clinical Research LLC | Austin | Texas | 78750 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 61 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05642312, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 20, 2025 · Synced Jul 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05642312 live on ClinicalTrials.gov.