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Completed Phase 3 Interventional

Vamikibart in Participants With Uveitic Macular Edema

ClinicalTrials.gov ID: NCT05642325

Public ClinicalTrials.gov record NCT05642325. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 27, 2026, 4:36 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Investigate the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Vamikibart Administered Intravitreally in Patients With Uveitic Macular Edema

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will assess the efficacy and safety of vamikibart in participants with uveitic macular edema.

Study identification

NCT ID
NCT05642325
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
256 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 23, 2023 (Actual)
Primary completion
May 7, 2025 (Actual)
Completion
Dec 24, 2025 (Actual)
Last update posted
Apr 17, 2026

2023 – 2025

United States locations

U.S. sites
23
U.S. states
12
U.S. cities
22
Facility City State ZIP Site status
Associated Retina Consultants Phoenix Arizona 85020 —
Barnet Dulaney Perkins Eye Center Sun City Arizona 85351 —
Retina Consultants of Orange County Fullerton California 92835 —
Northern California Retina Vitreous Associates Mountain View California 94040 —
California Eye Specialists Medical group Inc. Pasadena California 91107 —
Retina Consultants of Southern California Redlands California 92374 —
Kaiser Permanente Riverside Medical Center Riverside California 92505 —
University of California, Davis, Eye Center Sacramento California 95817 —
Retinal Consultants Med Group Sacramento California 95825 —
Advanced Research Deerfield Beach Florida 33064 —
Retina Group of Florida Fort Lauderdale Florida 33308 —
University Retina and Macula Associates, PC Oak Forest Illinois 60452 —
Cumberland Valley Retina PC Hagerstown Maryland 21740 —
University of Michigan, Kellogg Eye Center Ann Arbor Michigan 48105 —
Duke Eye Center Durham North Carolina 27710 —
Cleveland Clinic Cleveland Ohio 44195 —
Erie Retina Research Erie Pennsylvania 16507-1429 —
Mid Atlantic Retina Philadelphia Pennsylvania 19107 —
Retina Research Institute of Texas Abilene Texas 79606 —
Retina Consultants of Texas Bellaire Texas 77401 —
Retina Consultants of Texas Katy Texas 77494 —
Retina Group of Washington Fairfax Virginia 22031 —
University of Wisconsin Madison Wisconsin 53705 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05642325, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 17, 2026 · Synced Oct 27, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05642325 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →