A Multiple Dose Trial of Emraclidine in Elderly Participants and in Participants With Dementia Due to Alzheimer's Disease
Public ClinicalTrials.gov record NCT05644977. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1, Randomized, Placebo-controlled Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Emraclidine Following Multiple Oral Doses in Healthy Elderly Participants (Part A) and to Evaluate the Safety and Tolerability of Emraclidine in Participants With Dementia Due to Alzheimer's Disease (Part B)
Study identification
- NCT ID
- NCT05644977
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 17 participants
Conditions and interventions
Conditions
Interventions
- Emraclidine Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 55 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 1, 2022
- Primary completion
- Apr 13, 2025
- Completion
- Apr 13, 2025
- Last update posted
- May 1, 2025
2022 – 2025
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cypress, California | Cypress | California | 90630 | — |
| San Diego, California | San Diego | California | 92103 | — |
| Hialeah, Florida | Hialeah | Florida | 33014 | — |
| Decatur, Georgia | Decatur | Georgia | 30030 | — |
| Honolulu, Hawaii | Honolulu | Hawaii | 96817 | — |
| Overland Park, Kansas | Overland Park | Kansas | 66212 | — |
| Farmington Hills, Michigan | Farmington Hills | Michigan | 48334 | — |
| Marlton, New Jersey | Marlton | New Jersey | 08053 | — |
| Princeton, New Jersey | Princeton | New Jersey | 08540 | — |
| Staten Island, New York | Staten Island | New York | 10314 | — |
| North Canton, Ohio | North Canton | Ohio | 44720 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05644977, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 1, 2025 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05644977 live on ClinicalTrials.gov.