Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older
Public ClinicalTrials.gov record NCT05650554. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adults Aged 18 Years and Older
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and immunogenicity of a single intramuscular (IM) injection of up to 3 dose levels of Quadrivalent Influenza messenger ribonucleic acid (mRNA) Vaccine MRT5413 compared to an active control (QIVstandard-dose (SD), QIV high-dose (HD) \[adults ≥ 65 years of age only\], or quadrivalent recombinant influenza vaccine (RIV4)) in adults 18 years of age and older.
Study identification
- NCT ID
- NCT05650554
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 682 participants
Conditions and interventions
Conditions
Interventions
- Quadrivalent Influenza mRNA Vaccine MRT5413 Biological
- Quadrivalent Recombinant Influenza Vaccine Biological
- Quadrivalent Influenza Standard Dose Vaccine Biological
- Quadrivalent Influenza High-Dose Vaccine Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 11, 2022
- Primary completion
- Apr 1, 2024
- Completion
- Apr 1, 2024
- Last update posted
- Mar 18, 2025
2022 – 2024
United States locations
- U.S. sites
- 28
- U.S. states
- 13
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Velocity Clinical Research-Chula Vista Site Number : 8400061 | Chula Vista | California | 91911 | — |
| Velocity Gardena Site Number : 8400062 | Gardena | California | 90247 | — |
| Long Beach Clinical Trials Site Number : 8400052 | Long Beach | California | 90806 | — |
| Velocity Clinical Research, North Hollywood Site Number : 8400051 | North Hollywood | California | 91606 | — |
| California Research Foundation Site Number : 8400006 | San Diego | California | 92123-1881 | — |
| Accel Clinical Research-Deland Clinical Research Unit Site Number : 8400032 | DeLand | Florida | 32720-0834 | — |
| Velocity New Smyrna Beach Site Number : 8400063 | Edgewater | Florida | 32132 | — |
| SIMEDHealth, LLC Site Number : 8400014 | Gainesville | Florida | 32607 | — |
| Indago Research and Health Center Site Number : 8400044 | Hialeah | Florida | 33012 | — |
| Cenexel Research Centers of America Site Number : 8400011 | Hollywood | Florida | 33024 | — |
| Florida International Research Center Site Number : 8400045 | Miami | Florida | 33173 | — |
| Suncoast Research Associates, LLC Site Number : 8400060 | Miami | Florida | 33173 | — |
| Florida Pulmonary Research Center Site Number : 8400036 | Winter Park | Florida | 32789 | — |
| Meridian Clinical Research Site Number : 8400022 | Savannah | Georgia | 31406 | — |
| Velocity Clinical Research Site Number : 8400024 | Meridian | Idaho | 83642 | — |
| DM Clinical Research - Chicago Site Number : 8400025 | River Forest | Illinois | 60305 | — |
| Brengle Family Medicine Site Number : 8400039 | Indianapolis | Indiana | 46260 | — |
| Velocity Clinical Research Lincoln Site Number : 8400049 | Lincoln | Nebraska | 68510 | — |
| Meridian Clinical Research Site Number : 8400017 | Norfolk | Nebraska | 68701 | — |
| Velocity Clinical Research Site Number : 8400008 | Omaha | Nebraska | 68134 | — |
| Rochester Clinical Research. Inc. Site Number : 8400027 | Rochester | New York | 14609 | — |
| Velocity Clinical Research Site Number : 8400001 | Cleveland | Ohio | 44122 | — |
| Velocity Clinical Research - Providence Site Number : 8400019 | East Greenwich | Rhode Island | 02818 | — |
| Coastal Carolina Research Center Site Number : 8400042 | North Charleston | South Carolina | 29405 | — |
| ClinSearch Site Number : 8400013 | Chattanooga | Tennessee | 37421 | — |
| Elligo Health Research, Inc. Site Number : 8400002 | Austin | Texas | 78704 | — |
| DM Clinical Research- Bellaire Site Number : 8400026 | Houston | Texas | 77081 | — |
| Clinical Trials of Texas, Inc. - PPDS Site Number : 8400016 | San Antonio | Texas | 78229 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05650554, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 18, 2025 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05650554 live on ClinicalTrials.gov.