Study to Evaluate ARINA-1 in the Prevention of Bronchiolitis Obliterans Progression in Participants With Bilateral Lung Transplant

ClinicalTrials.gov ID: NCT05654922

Public ClinicalTrials.gov record NCT05654922. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Jul 23, 2026, 3:27 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Open-label, Randomized, Standard of Care-controlled, Parallel Study Arm Study to Demonstrate Efficacy and Safety of ARINA-1 in the Prevention of Bronchiolitis Obliterans Syndrome (BOS) Progression in Participants With a Bilateral Lung Transplant

Study identification

NCT ID: NCT05654922
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Renovion, Inc.; Industry
Enrollment: 100 participants

Conditions and interventions

Conditions

Pre-Bronchiolitis Obliterans Syndrome

Interventions

ARINA-1 Drug
Standard of care only Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Apr 9, 2023
Primary completion: Apr 30, 2026
Completion: Oct 31, 2026
Last update posted: Dec 8, 2025

2023 – 2026

United States locations

U.S. sites: 20
U.S. states: 14
U.S. cities: 18

Facility	City	State	ZIP	Site status
Dignity Health - St. Joseph's Hospital and Medical Center	Phoenix	Arizona	85013	Withdrawn
University of California Los Angeles School of Medicine	Los Angeles	California	90095	Recruiting
University of California San Diego Health	San Diego	California	92103	Recruiting
Advent Health	Orlando	Florida	32803	Recruiting
University of South Florida	Tampa	Florida	33606	Recruiting
Loyola University Medical Center	Maywood	Illinois	60153	Recruiting
University of Iowa Hospital	Iowa City	Iowa	52242	Recruiting
Johns Hopkins Hospital	Baltimore	Maryland	21287	Recruiting
University of Minnesota Medical School	Minneapolis	Minnesota	55455	Withdrawn
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Columbia University Irving Medical Center	New York	New York	10032	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
The Ohio State University Wexner Medical Center	Columbus	Ohio	43221	Recruiting
Temple University Hospital	Philadelphia	Pennsylvania	19122	Not yet recruiting
Medical University of South Carolina	Charleston	South Carolina	29452	Recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	45390	Recruiting
Baylor Scott and White Research Institute	Dallas	Texas	75246	Recruiting
Baylor St. Luke's Medical Center	Houston	Texas	77030	Recruiting
Houston Methodist Hospital	Houston	Texas	77030	Recruiting
Inova Fairfax Hospital	Falls Church	Virginia	22042	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05654922, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Dec 8, 2025 · Synced Jul 23, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05654922 live on ClinicalTrials.gov.

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