A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease
Public ClinicalTrials.gov record NCT05655520. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Multicenter, Open-label Safety Study to Evaluate the Long-term Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The primary purpose of the study is to evaluate the safety and tolerability of SAGE-718 softgel lipid capsule in participants with Huntington's Disease (HD)
Study identification
- NCT ID
- NCT05655520
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 153 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 25 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 14, 2022 (Actual)
- Primary completion
- Jan 20, 2025 (Actual)
- Completion
- Jan 20, 2025 (Actual)
- Last update posted
- Dec 17, 2025
2022 – 2025
United States locations
- U.S. sites
- 29
- U.S. states
- 21
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sage Investigational Site | Birmingham | Alabama | 35233 | — |
| Sage Investigational Site | Little Rock | Arkansas | 72205 | — |
| Sage Investigational Site | La Jolla | California | 92037 | — |
| Sage Investigational Site | Los Alamitos | California | 90720 | — |
| Sage Investigational Site | Los Angeles | California | 90095 | — |
| Sage Investigational Site | Sacramento | California | 95817 | — |
| Sage Investigational Site | Englewood | Colorado | 80113 | — |
| Sage Investigational Site | Washington D.C. | District of Columbia | 20007 | — |
| Sage Investigational Site | Boca Raton | Florida | 33431 | — |
| Sage Investigational Site | Tampa | Florida | 33612 | — |
| Sage Investigational Site | Chicago | Illinois | 60611 | — |
| Sage Investigational Site | Chicago | Illinois | 60612 | — |
| Sage Investigational Site | Indianapolis | Indiana | 46202 | — |
| Sage Investigational Site | Iowa City | Iowa | 52242 | — |
| Sage Investigational Site | Kansas City | Kansas | 66103 | — |
| Sage Investigational Site | Baltimore | Maryland | 21287 | — |
| Sage Investigational Site | Boston | Massachusetts | 02215 | — |
| Sage Investigational Site | New York | New York | 10032 | — |
| Sage Investigational Site | Williamsville | New York | 14221 | — |
| Sage Investigational Site | Chapel Hill | North Carolina | 27599 | — |
| Sage Investigational Site | Durham | North Carolina | 27705 | — |
| Sage Investigational Site | Cincinnati | Ohio | 45219 | — |
| Sage Investigational Site | Toledo | Ohio | 43614 | — |
| Sage Investigational Site | Philadelphia | Pennsylvania | 19107 | — |
| Sage Investigational Site | Charleston | South Carolina | 29425 | — |
| Sage Investigational Site | Memphis | Tennessee | 38157 | — |
| Sage Investigational Site | Houston | Texas | 77030 | — |
| Sage Investigational Site | Richmond | Virginia | 23298 | — |
| Sage Investigational Site | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05655520, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 17, 2025 · Synced Nov 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05655520 live on ClinicalTrials.gov.