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Not listed Not applicable Interventional Accepts healthy volunteers

Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser for Treatment of Facial Melasma

ClinicalTrials.gov ID: NCT05656833

Public ClinicalTrials.gov record NCT05656833. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 3, 2026, 6:46 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Combination Topical Cysteamine and Fractional 1927nm Low-Powered Diode Laser

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of our study is to determine the efficacy of combined topical cysteamine cream with a 1927 diode non-ablative laser (Clear + Brilliant Permea®; Solta Medical, Inc.), compared to topical cysteamine (Cyspera) alone in the treatment of melasma. The main questions it aims to answer are * If melasma treatment with topical cysteamine cream is more effective when used with the Clear \& Brilliant® Permea laser * The safety \& efficacy of melasma treatment in various skin types using the Clear \& Brilliantt® Permea laser in combination with topical cysteamine. Participants will * Come into our office for an initial screening appointment to determine if participant is eligible for the study * Come in for 3 laser treatments, 4 weeks apart, on 1 side of the face * Use the study provided Cyspera topical cream every day on the entire face for the 12 weeks on the study. Researchers will compare the side of the participants face not treated with laser to the side of the face treated with laser. The participants will be using Cyspera on both sides of their face.

Study identification

NCT ID
NCT05656833
Recruitment status
Not listed
Study type
Interventional
Phase
Not applicable
Lead sponsor
UnionDerm
Other
Enrollment
20 participants

Conditions and interventions

Conditions

Interventions

Device · Other

Eligibility (public fields only)

Age range
18 Years to 74 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Oct 27, 2022
Primary completion
Mar 31, 2023
Completion
Jun 30, 2023
Last update posted
Dec 18, 2022

2022 – 2023

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
UnionDerm New York New York 10003 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05656833, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Dec 18, 2022 · Synced Sep 3, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05656833 live on ClinicalTrials.gov.

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