Study of SDX in Patients With Idiopathic Hypersomnia (IH)
Public ClinicalTrials.gov record NCT05668754. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Placebo-Controlled, Double-Blind, Randomized Withdrawal Study to Determine the Safety and Efficacy of Oral SDX in Patients With Idiopathic Hypersomnia (IH)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a study of the safety, efficacy and pharmacokinetics (PK) of Serdexmethylphenidate (SDX) compared to placebo in subjects with Idiopathic Hypersomnia (IH).
Study identification
- NCT ID
- NCT05668754
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 66 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 28, 2022 (Actual)
- Primary completion
- Feb 28, 2024 (Actual)
- Completion
- Mar 21, 2024 (Actual)
- Last update posted
- Jun 30, 2026
2022 – 2024
United States locations
- U.S. sites
- 41
- U.S. states
- 18
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sleep Disorders Center Of Alabama | Birmingham | Alabama | 35201 | — |
| Amr Daphne | Daphne | Alabama | 36526 | — |
| Lakeview Clinical Research | Guntersville | Alabama | 35976 | — |
| SOCAL Clinical Research | Huntington Beach | California | 92647 | — |
| Stanford University | Redwood City | California | 94063 | — |
| Sleep Medicine Specialists of California | San Ramon | California | 94583 | — |
| SDS Clinical Trials, Inc | Santa Ana | California | 92701 | — |
| Delta Waves, Inc. | Colorado Springs | Colorado | 80903 | — |
| Saint Francis Sleep Allergy and Lung Institute LLC | Clearwater | Florida | 33755 | — |
| New Generation of Medical Trials | Hialeah | Florida | 33010 | — |
| Angels Clinical Research | Miami | Florida | 33122 | — |
| Ivetmar Medical Group | Miami | Florida | 33130 | — |
| Somnology Research Associates | Miami | Florida | 33130 | — |
| Clinical Trial Services, Corp | Miami | Florida | 33144 | — |
| Pasadena Center for Medical Research | St. Petersburg | Florida | 33707 | — |
| Clinical Site Partners, LLC - Winter Park | Winter Park | Florida | 32789 | — |
| Global Research Associates | Atlanta | Georgia | 30303 | — |
| Neurotrials Research, Inc | Atlanta | Georgia | 30303 | — |
| Clinical Research Institute - Stockbridge | Stockbridge | Georgia | 30281 | — |
| The University of Kansas Medical Center Research Institution Inc. | Kansas City | Kansas | 64106 | — |
| Mid-Atlantic Epilepsy and Sleep Center - Bethesda | Bethesda | Maryland | 20817 | — |
| Neurocare, Inc. | Newton | Massachusetts | 02459 | — |
| Western Michigan University Homer Stryker Md School of Medicine | Kalamazoo | Michigan | 49007 | — |
| Henry Ford Health - Columbus | Novi | Michigan | 48375 | — |
| Clinical Neurophysiology Services PC | Sterling Heights | Michigan | 48313 | — |
| University of Missouri School Of Medicine | Columbia | Missouri | 65211 | — |
| Clayton Sleep Institute, Llc | St Louis | Missouri | 63123 | — |
| Barrett Clinic | La Vista | Nebraska | 68128 | — |
| Global Medical Institutes LLC- Princeton Medical Institute | Lawrence | New Jersey | 08648 | — |
| Clinical Research of Gastonia (CRG) | Gastonia | North Carolina | 28052 | — |
| Intrepid Research | Cincinnati | Ohio | 45202 | — |
| Ohio Sleep Medicine Institute | Dublin | Ohio | 43017 | — |
| Brian Abaluck, LLC | Malvern | Pennsylvania | 19355 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Medical University Of South Carolina (MUSC) - Institute Of Psychiatry (IOP) | Charleston | South Carolina | 29401 | — |
| Bogan Sleep Consultants | Columbia | South Carolina | 29201 | — |
| Futuresearch Trials Of Neurology | Austin | Texas | 78701 | — |
| Dfw Clinical Research Associates | Fort Worth | Texas | 76244 | — |
| Houston Clinical Research Associates | Houston | Texas | 77002 | — |
| Sleep Therapy & Research Center | San Antonio | Texas | 78205 | — |
| TPMG Clinical Research - Williamsburg | Williamsburg | Virginia | 23185 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05668754, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 30, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05668754 live on ClinicalTrials.gov.