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Completed Phase 2Phase 3 Interventional Results available

A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD

ClinicalTrials.gov ID: NCT05686044

Public ClinicalTrials.gov record NCT05686044. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 23, 2026, 7:40 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study of Buntanetap in Participants With Mild to Moderate Alzheimer's Disease

Study identification

NCT ID
NCT05686044
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2, Phase 3
Lead sponsor
Annovis Bio Inc.
Industry
Enrollment
351 participants

Conditions and interventions

Interventions

  • Buntanetap/Posiphen Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
55 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 31, 2023
Primary completion
Feb 12, 2024
Completion
Feb 12, 2024
Last update posted
Apr 28, 2025

2023 – 2024

United States locations

U.S. sites
54
U.S. states
19
U.S. cities
45
Facility City State ZIP Site status
CCT Research - Gilbert Neurology Partners Gilbert Arizona 85297
CCT Research - Foothills Center Phoenix Arizona 85004
The Belinga Clinic Fort Smith Arkansas 72916
Sun Valley Research Center Imperial California 92251
CenExel Clinical Clinical Research, Inc Los Alamitos California 90720
Cenexel Rocky Mountain Clinical Research Englewood Colorado 80113
Ki Health Partners LLC D/B/A New England Institute for Clinical Research Stamford Connecticut 06824
Visionary Investigators Network Aventura Florida 33180
K2 Medical Research Clermont Florida 34711
The Neurology Institute - Coral Springs Coral Springs Florida 33067-4640
JY Research Inst. Cutler Bay Florida 33189
Arrow Clinical trial Daytona Beach Florida 32114
Accel Research Sites - DeLand Clinical Research Unit DeLand Florida 32720
New Life Medical Research Center Hialeah Florida 33012
CenExel RCA Hollywood Florida 33024
Coral Clinic Reserach LLC Homestead Florida 33032
Charter Research Lady Lake Florida 32159
ClinCloud, LLC Maitland Florida 32751
K2 Medical Research Maitland Florida 32751
Merritt Island Clinical Research LLC Merritt Island Florida 32952
Premier Clinical Research Institute, Inc Miami Florida 33122
Gold Coast Health Research, LLC Miami Florida 33155
Medical Professional Clinical Research Center, Inc Miami Florida 33165
Reliant Medical Research Miami Florida 33165
Ezy Medical Research Co. Miami Florida 33175
Nuovida Research Center Miami Florida 33186
Renstar Medical Research Ocala Florida 34470
Visionary Investigators Network Pembroke Pines Florida 33026
Napa Research Pompano Beach Florida 33064
K2 Medical Research Tampa Florida 33067
K2 Summit Research The Villages Florida 32159
ClinCloud, LLC Viera Florida 32940
Conquest Research, LLC Winter Park Florida 32789
Charter Research Winter Park Florida 32792
CenExel iResearch, LLC Decatur Georgia 30030
Center for Advanced Research & Education Gainesville Georgia 30501
Hawaii Pacific Neuroscience, LLC Honolulu Hawaii 96817
Southern Illinois University School of Medicine Springfield Illinois 62702
Josephson Wallack Munshower Neurology, P.C. Indianapolis Indiana 46256
Northern Light Acadia Hospital Bangor Maine 04401
MedVadis Research Waltham Massachusetts 02451
Quest Research Institue Farmington Hills Michigan 48334
Insight Research Institute Flint Michigan 48507
Hassman Research Institute Berlin New Jersey 08009
CenExel Clinical Research, Inc Toms River New Jersey 08755
Velocity Clinical Research Syracuse New York 13057
SUNY Upstate Medical University Syracuse New York 13210
Duke University Durham North Carolina 27705
Neuroscience Centre (CINAC) Canton Ohio 44718
Dayton Center for Neurological Disorders, Inc Centerville Ohio 45459
NeuroCare Plus Houston Texas 77094
Be Well Clinical Studies, LLC Round Rock Texas 78681
Central Texas Neurology Consultants Round Rock Texas 78681
Inland Northwest Research Spokane Washington 99202-1342

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05686044, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 28, 2025 · Synced Jul 23, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05686044 live on ClinicalTrials.gov.

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