A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD
Public ClinicalTrials.gov record NCT05686044. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Multicenter Study of Buntanetap in Participants With Mild to Moderate Alzheimer's Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to measure efficacy and safety of three different doses of buntanetap/Posiphen compared with placebo in participants with mild to moderate Alzheimer's disease. Study details include: The double-blind treatment duration will include a screening period of up to 42 days followed by 12 weeks of treatment at home. The study duration will be 4-5 months. There will be 4 in-clinic visits and 1 phone call.
Study identification
- NCT ID
- NCT05686044
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2, Phase 3
- Enrollment
- 351 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 1, 2023 (Actual)
- Primary completion
- Feb 13, 2024 (Actual)
- Completion
- Feb 13, 2024 (Actual)
- Last update posted
- Apr 29, 2025
2023 – 2024
United States locations
- U.S. sites
- 54
- U.S. states
- 19
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| CCT Research - Gilbert Neurology Partners | Gilbert | Arizona | 85297 | — |
| CCT Research - Foothills Center | Phoenix | Arizona | 85004 | — |
| The Belinga Clinic | Fort Smith | Arkansas | 72916 | — |
| Sun Valley Research Center | Imperial | California | 92251 | — |
| CenExel Clinical Clinical Research, Inc | Los Alamitos | California | 90720 | — |
| Cenexel Rocky Mountain Clinical Research | Englewood | Colorado | 80113 | — |
| Ki Health Partners LLC D/B/A New England Institute for Clinical Research | Stamford | Connecticut | 06824 | — |
| Visionary Investigators Network | Aventura | Florida | 33180 | — |
| K2 Medical Research | Clermont | Florida | 34711 | — |
| The Neurology Institute - Coral Springs | Coral Springs | Florida | 33067-4640 | — |
| JY Research Inst. | Cutler Bay | Florida | 33189 | — |
| Arrow Clinical trial | Daytona Beach | Florida | 32114 | — |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | 32720 | — |
| New Life Medical Research Center | Hialeah | Florida | 33012 | — |
| CenExel RCA | Hollywood | Florida | 33024 | — |
| Coral Clinic Reserach LLC | Homestead | Florida | 33032 | — |
| Charter Research | Lady Lake | Florida | 32159 | — |
| ClinCloud, LLC | Maitland | Florida | 32751 | — |
| K2 Medical Research | Maitland | Florida | 32751 | — |
| Merritt Island Clinical Research LLC | Merritt Island | Florida | 32952 | — |
| Premier Clinical Research Institute, Inc | Miami | Florida | 33122 | — |
| Gold Coast Health Research, LLC | Miami | Florida | 33155 | — |
| Medical Professional Clinical Research Center, Inc | Miami | Florida | 33165 | — |
| Reliant Medical Research | Miami | Florida | 33165 | — |
| Ezy Medical Research Co. | Miami | Florida | 33175 | — |
| Nuovida Research Center | Miami | Florida | 33186 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Visionary Investigators Network | Pembroke Pines | Florida | 33026 | — |
| Napa Research | Pompano Beach | Florida | 33064 | — |
| K2 Medical Research | Tampa | Florida | 33067 | — |
| K2 Summit Research | The Villages | Florida | 32159 | — |
| ClinCloud, LLC | Viera | Florida | 32940 | — |
| Conquest Research, LLC | Winter Park | Florida | 32789 | — |
| Charter Research | Winter Park | Florida | 32792 | — |
| CenExel iResearch, LLC | Decatur | Georgia | 30030 | — |
| Center for Advanced Research & Education | Gainesville | Georgia | 30501 | — |
| Hawaii Pacific Neuroscience, LLC | Honolulu | Hawaii | 96817 | — |
| Southern Illinois University School of Medicine | Springfield | Illinois | 62702 | — |
| Josephson Wallack Munshower Neurology, P.C. | Indianapolis | Indiana | 46256 | — |
| Northern Light Acadia Hospital | Bangor | Maine | 04401 | — |
| MedVadis Research | Waltham | Massachusetts | 02451 | — |
| Quest Research Institue | Farmington Hills | Michigan | 48334 | — |
| Insight Research Institute | Flint | Michigan | 48507 | — |
| Hassman Research Institute | Berlin | New Jersey | 08009 | — |
| CenExel Clinical Research, Inc | Toms River | New Jersey | 08755 | — |
| Velocity Clinical Research | Syracuse | New York | 13057 | — |
| SUNY Upstate Medical University | Syracuse | New York | 13210 | — |
| Duke University | Durham | North Carolina | 27705 | — |
| Neuroscience Centre (CINAC) | Canton | Ohio | 44718 | — |
| Dayton Center for Neurological Disorders, Inc | Centerville | Ohio | 45459 | — |
| NeuroCare Plus | Houston | Texas | 77094 | — |
| Be Well Clinical Studies, LLC | Round Rock | Texas | 78681 | — |
| Central Texas Neurology Consultants | Round Rock | Texas | 78681 | — |
| Inland Northwest Research | Spokane | Washington | 99202-1342 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05686044, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2025 · Synced Nov 5, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05686044 live on ClinicalTrials.gov.