ClinicalTrials.gov record
A Study to Test Asundexian for Preventing a Stroke Caused by a Clot in Participants After an Acute Ischemic Stroke or After a High-risk Transient Ischemic Attack, a So-called Mini Stroke
ClinicalTrials.gov ID: NCT05686070
Public ClinicalTrials.gov record NCT05686070. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 19, 2026, 8:39 PM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, International, Randomized, Placebo Controlled, Double-blind, Parallel Group and Event Driven Phase 3 Study of the Oral FXIa Inhibitor Asundexian (BAY 2433334) for the Prevention of Ischemic Stroke in Male and Female Participants Aged 18 Years and Older After an Acute Non-cardioembolic Ischemic Stroke or High-risk TIA
Study identification
- NCT ID
- NCT05686070
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Bayer
- Industry
- Enrollment
- 12,327 participants
Conditions and interventions
Conditions
Interventions
- Asundexian (BAY2433334) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 25, 2023
- Primary completion
- Oct 22, 2025
- Completion
- Oct 22, 2025
- Last update posted
- Nov 11, 2025
2023 – 2025
United States locations
- U.S. sites
- 108
- U.S. states
- 32
- U.S. cities
- 90
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Eastern Shore Research Institute, LLC | Fairhope, AL | Fairhope | Alabama | 36532 | — |
| Barrow Neurologic Institute - Petznick Stroke Center | Phoenix | Arizona | 85013 | — |
| HonorHealth Research Institute | Scottsdale | Arizona | 85258 | — |
| Banner - University Medical Center Tucson - Neurology | Tucson | Arizona | 85724 | — |
| University of Arkansas for Medical Sciences - Neurology | Little Rock | Arkansas | 72205 | — |
| Kaiser Permanente Fontana Medical Center | Fontana | California | 92335 | — |
| Long Beach Medical Center - Neurology | Long Beach | California | 90806 | — |
| Kaiser Permanente Los Angeles Medical Center - Neurology | Los Angeles | California | 90027 | — |
| Los Angeles - USC Healthcare Center 2 - Neurology | Los Angeles | California | 90033 | — |
| UCLA NeuroTranslational Research Center | Los Angeles | California | 90095 | — |
| Hoag Memorial Hospital - Center for Research & Education | Newport Beach | California | 92663 | — |
| UCI Medical Center - Neurology | Orange | California | 92868 | — |
| San Francisco VA Health Care System | San Francisco | California | 94121 | — |
| Cottage Health | Santa Barbara Cottage Hospital - Research Department | Santa Barbara | California | 93105 | — |
| The Lundquist Institute - Neurology | Torrance | California | 90502 | — |
| St. Vincent's Medical Center - Neurology Clinic | Bridgeport | Connecticut | 06606 | — |
| Nuvance Health | Danbury | Connecticut | 06810 | — |
| Yale University | School of Medicine - Department of Neurology | New Haven | Connecticut | 06519 | — |
| ChristianaCare Health Services | Christiana Hospital - Emergency Medicine Research | Newark | Delaware | 19718 | — |
| HCA Florida JFK Hospital - Neurology | Atlantis | Florida | 33462 | — |
| Delray Medical Center - Neurology | Boynton Beach | Florida | 33472 | — |
| Nova Clinical Research - Blake Medical Center | Bradenton | Florida | 34209 | — |
| BayCare Health System | Morton Plant Hospital - Neuroscience Research department | Clearwater | Florida | 33756 | — |
| UF Health Neuromedicine Hospital | Gainesville | Florida | 32608 | — |
| Baptist Health Research Institute | Jacksonville | Florida | 32207 | — |
| Intercoastal Medical Group | Clinical Research | Sarasota | Florida | 34239 | — |
| USF Health South Tampa Center for Advanced Healthcare - Neurology | Tampa | Florida | 33606 | — |
| BayCare Health System | Saint Joseph's Hospital - Neurology Department | Tampa | Florida | 33607 | — |
| University of Illinois Hospital - Neurology | Chicago | Illinois | 60612 | — |
| The University of Chicago Medical Center - Neurology | Chicago | Illinois | 60637 | — |
| Loyola University Medical Center - Neurology | Maywood | Illinois | 60153 | — |
| Mercyhealth Javon Bea Hospital - Riverside | Neurology Research Department | Rockford | Illinois | 61114 | — |
| HSHS St. John's Hospital - Neurology | Springfield | Illinois | 62769 | — |
| Baptist Health Lexington | Lexington | Kentucky | 40503 | — |
| Ochsner Medical Center - New Orleans - Neurology | New Orleans | Louisiana | 70121 | — |
| University of Maryland Medical Center - Neurology Care Center | Baltimore | Maryland | 21201 | — |
| Tufts Medical Center - Neurology | Boston | Massachusetts | 02111 | — |
| Henry Ford Hospital - Neurology | Detroit | Michigan | 48202 | — |
| MSU Health Care Neurology & Ophthalmology | East Lansing | Michigan | 48824 | — |
| Trinity Health | Oakland Hospital - Clinical Research Department | Pontiac | Michigan | 48341 | — |
| Minneapolis Clinic of Neurology | Golden Valley, MN | Golden Valley | Minnesota | 55422 | — |
| Mayo Clinic - Rochester - Neurology | Rochester | Minnesota | 55902 | — |
| University Hospital - UMMC - Neurology | Jackson | Mississippi | 39216 | — |
| Saint Luke's Hospital of Kansas City - Neurology | Kansas City | Missouri | 64111 | — |
| Kansas City VA Medical Center - Neurology | Kansas City | Missouri | 64128 | — |
| Barnes-Jewish Hospital - Cardiology | St Louis | Missouri | 63100 | — |
| Mercy Research - St. Louis | St Louis | Missouri | 63141 | — |
| Dartmouth-Hitchcock Medical Center - Neurology | Lebanon | New Hampshire | 03756 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| Albany Medical College | Department of Neurology | Albany | New York | 12208 | — |
| SUNY Downstate Health Sciences University - Neurology | Brooklyn | New York | 11203 | — |
| NYU Langone Hospital Brooklyn - Neurology | Brooklyn | New York | 11220 | — |
| Mount Sinai Brooklyn - Neurology | Brooklyn | New York | 11234 | — |
| Trinity Medical Western New York | Trinity Vascular & Endovascular Center - Research Department | Buffalo | New York | 14220 | — |
| Neuroscience Institute at Great Neck | Great Neck | New York | 11021 | — |
| Westchester Medical Center | Hawthorne | New York | 10532 | — |
| The Neurological Institute - Columbia University Irving Medical Center | New York | New York | 10032 | — |
| Mount Sinai Hospital - Stroke Center | New York | New York | 33756 | — |
| Vassar Brothers Medical Center | Poughkeepsie | New York | 12601 | — |
| Rochester General Hospital | Rochester | New York | 14621 | — |
| Mission Hospital | Neurology | Asheville | North Carolina | 28801 | — |
| Duke Neurological Disorders Clinic - Clinic 1L | Durham | North Carolina | 27710 | — |
| Guilford Neurologic Research Partners, LLC. | Greensboro | North Carolina | 27405 | — |
| ECU Health Medical Center - Neurology | Greenville | North Carolina | 27834 | — |
| North Carolina Heart & Vascular (Capital Heart) | Raleigh | North Carolina | 27607 | — |
| Novant Health Forsyth Medical Center - Neurology | Winston-Salem | North Carolina | 27103 | — |
| Atrium Health Wake Forest Baptist | Medical Center - Neurology Department | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic - Neurology | Cleveland | Ohio | 44195 | — |
| Ohio State University Wexner Medical Center - Neurology | Columbus | Ohio | 43210 | — |
| OhioHealth Neuroscience Center at Riverside | Columbus | Ohio | 43214 | — |
| Wright State University | Boonshoft School of Medicine - WSU and Premier Health Clinical Trials Research Alliance | Dayton | Ohio | 45409 | — |
| Kettering Health Main Campus - Neurology | Kettering | Ohio | 45429 | — |
| Mercy Health - St. Rita's Medical Center - Neurology | Lima | Ohio | 45801 | — |
| ProMedica | ProMedica Toledo Hospital - Neuro/Stroke Research Department | Toledo | Ohio | 43606 | — |
| Mercy Health St. Vincent Medical Center - Neurology | Toledo | Ohio | 43608 | — |
| Mercy Health St. Elizabeth Youngstown Hospital - Neurology | Youngstown | Ohio | 44504 | — |
| OU Health University of Oklahoma Med Center - Neurology | Oklahoma City | Oklahoma | 73104 | — |
| Mercy Hospital Oklahoma City | Oklahoma City | Oklahoma | 73120 | — |
| OHSU Hospital - Neurology | Portland | Oregon | 97239 | — |
| LVH Neurology - 1250 Cedar Crest | Allentown | Pennsylvania | 18103 | — |
| University of Pittsburgh Medical Center, Hamot | Clinical Trials and Research | Erie | Pennsylvania | 16507 | — |
| UPMC Harrisburg - Cardiology | Harrisburg | Pennsylvania | 17101 | — |
| Penn State Milton S. Hershey Medical Center - Neurology | Hershey | Pennsylvania | 17033 | — |
| Lancaster General Health Neuroscience Institute | Lancaster | Pennsylvania | 17601 | — |
| Hospital of the University of Pennsylvania - Neurology | Philadelphia | Pennsylvania | 19104 | — |
| Jefferson Hospital for Neuroscience | Philadelphia | Pennsylvania | 19107 | — |
| Lewis Katz School of Medicine at Temple University | Neurology | Philadelphia | Pennsylvania | 19140 | — |
| Jefferson Einstein Philadelphia Hospital - Neurology | Philadelphia | Pennsylvania | 19141 | — |
| Rhode Island Hospital - Neurology | Providence | Rhode Island | 20903 | — |
| MUSC Health Neurology at Rutledge Tower | Charleston | South Carolina | 29425 | — |
| Prisma Health Greenville Memorial Hospital - Comprehensive Stroke Center | Greenville | South Carolina | 29605 | — |
| Erlanger Neurology | Chattanooga | Tennessee | 37403 | — |
| The University of Tennessee Medical Center - Main Campus - Neurology | Knoxville | Tennessee | 37920 | — |
| Baptist Memorial Hospital East - Cardiology | Memphis | Tennessee | 38120 | — |
| Baylor University Medical Center at Dallas - Neurology | Dallas | Texas | 75204 | — |
| James W. Aston Ambulatory Care Center - Neurology | Dallas | Texas | 75390 | — |
| Doctors Hospital at Renaissance - Neurology | Edinburg | Texas | 78539 | — |
| Texas Health Harris Methodist Hospital - Fort Worth - Neurology | Fort Worth | Texas | 76104 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| UTHealth Houston Neurosciences Neurology - Texas Medical Center | Houston | Texas | 77030 | — |
| Neurology Consultants of Dallas - Plano | Plano | Texas | 75093 | — |
| UT Health San Antonio - Medical Arts & Research Center - Neurology | San Antonio | Texas | 78229 | — |
| Baylor Scott & White Medical Center - Temple - Neurology | Temple | Texas | 76508 | — |
| Intermountain Cardiovascular Research Department | Murray | Utah | 84107 | — |
| University of Utah Clinical Neurosciences Center | Salt Lake City | Utah | 84312 | — |
| Neurological Associates - Henrico | Henrico | Virginia | 23229 | — |
| Marshall University Medical Center - Neurology | Huntington | West Virginia | 25701 | — |
| Froedtert Hospital - Neurology | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 633 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05686070, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 11, 2025 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05686070 live on ClinicalTrials.gov.