ClinicalTrials.gov record
A Study of Milvexian in Participants After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack- LIBREXIA-STROKE
ClinicalTrials.gov ID: NCT05702034
Public ClinicalTrials.gov record NCT05702034. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of Milvexian, an Oral Factor XIa Inhibitor, for Stroke Prevention After an Acute Ischemic Stroke or High-Risk Transient Ischemic Attack
Study identification
- NCT ID
- NCT05702034
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 12,532 participants
Conditions and interventions
Conditions
Not listed
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 14, 2023
- Primary completion
- Nov 10, 2026
- Completion
- Dec 8, 2026
- Last update posted
- May 7, 2026
2023 – 2026
United States locations
- U.S. sites
- 127
- U.S. states
- 33
- U.S. cities
- 105
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner Desert Medical Center | Mesa | Arizona | 85202 | — |
| University of Arizona | Tucson | Arizona | 85721 | — |
| Plaza Neuroscience Clinic | Fayetteville | Arkansas | 72703-3902 | — |
| Alta Bates Medical Center Cancer Center | Berkeley | California | 94705 | — |
| Providence Saint Joseph Medical Center - Cancer Center | Burbank | California | 91505 | — |
| Mills Peninsula Health Services | Burlingame | California | 94010 | — |
| Sutter Health - Eden Medical Center | Castro Valley | California | 94546 | — |
| Neurology Center of North Orange County | Fullerton | California | 92835 | — |
| Glendale Adventist Medical Center | Glendale | California | 91206 | — |
| UC Irvine Healthcare Center | Irvine | California | 92697 | — |
| Sharp Grossmont Hospital | La Mesa | California | 91942 | — |
| Long Beach Memorial | Long Beach | California | 90806 | — |
| Kaiser Permanente Los Angeles Medical Center | Los Angeles | California | 90027 | — |
| Mission Hospital Regional Medical Center | Mission Viejo | California | 92691 | — |
| Hoag Memorial Hospital | Newport Beach | California | 92663 | — |
| Stanford Stroke Center | Palo Alto | California | 94304-1419 | — |
| Kaiser Permanente 1 | Redwood City | California | 94063 | — |
| University of California Davis Health System | Sacramento | California | 95817 | — |
| Kaiser Permanente | Sacramento | California | 95825-2115 | — |
| California Pacific Medical Center | San Francisco | California | 94115 | — |
| Pacific Neuroscience Institute | Santa Monica | California | 90404 | — |
| Harbor Ucla Medical Center | Torrance | California | 90502 | — |
| Providence Little Company of Mary | Torrance | California | 90503 | — |
| PIH Health Hospital | Whittier | California | 90602 | — |
| University of Colorado | Aurora | Colorado | 80045 | — |
| Nuvance Health Medical Practices Cardiology Danbury | Danbury | Connecticut | 06810 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| MedStar Health Research Institute | Washington D.C. | District of Columbia | 20010 | — |
| Boca Raton Regional Hospital | Boca Raton | Florida | 33486 | — |
| Nova Clinical Research, LLC 1 | Bradenton | Florida | 34209 | — |
| Nova Clinical Research, LLC | Bradenton | Florida | 34209 | — |
| Morton Plant Hospital | Clearwater | Florida | 33756-3394 | — |
| Baptist Health 1 | Miami | Florida | 33173 | — |
| Advent Health Orlando | Orlando | Florida | 32804-5521 | — |
| Sacred Heart Hospital | Pensacola | Florida | 32504 | — |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | — |
| Theia Clincial Research, LLC | Temple Terrace | Florida | 33617 | — |
| Saint Marys Medical Center | West Palm Beach | Florida | 33407 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Saint Alphonsus Regional Medical Center- Cancer Care Center | Boise | Idaho | 83706 | — |
| Rush University Medical Center | Chicago | Illinois | 60612 | — |
| Insight Hospital and Medical Center Chicago | Chicago | Illinois | 60616 | — |
| Northshore University Healthsystem | Evanston | Illinois | 60201 | — |
| St. Joseph's Regional Medical Center | Joliet | Illinois | 60435 | — |
| OSF Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| Blessing Hospital | Quincy | Illinois | 62301 | — |
| Javon Bea Hospital | Rockford | Illinois | 61114 | — |
| Prairie Education And Research Cooperative | Springfield | Illinois | 62769 | — |
| Parkview Research Center | Fort Wayne | Indiana | 46845 | — |
| IU Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Community Hospital Cardiovascular Research | Munster | Indiana | 46321 | — |
| University of Kansas Medical Center Research Institute | Kansas City | Kansas | 66160 | — |
| Ascension via Christi Research | Wichita | Kansas | 67214 | — |
| University of Kentucky Medical Center | Lexington | Kentucky | 40506 | — |
| University of Louisville | Louisville | Kentucky | 40202 | — |
| Pikeville Medical Center | Pikeville | Kentucky | 41537 | — |
| Sinai Hospital of Baltimore | Baltimore | Maryland | 21215 | — |
| Shady Grove Office | Rockville | Maryland | 20850 | — |
| Comprehensive Neurology Services | Silver Spring | Maryland | 20902 | — |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02216 | — |
| Detroit Medical Center | Detroit | Michigan | 48201 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| St John Hospital and Medical Center | Detroit | Michigan | 48236 | — |
| Michigan State University | East Lansing | Michigan | 48824 | — |
| Detroit Clinical Research Center | Farmington Hills | Michigan | 48334 | — |
| Memorial Institute for Neurosciences and Multiple Sclerosis | Owosso | Michigan | 48867 | — |
| William Beaumont Hospital 1 | Royal Oak | Michigan | 48073 | — |
| William Beaumont Hospital | Royal Oak | Michigan | 48073 | — |
| Providence & Providence Park Hospital | Southfield | Michigan | 48075 | — |
| M Health Fairview Ridges Hospital | Burnsville | Minnesota | 55337 | — |
| Fairview Southdale Hospital | Edina | Minnesota | 55435 | — |
| University Of Minnesota Medical Center | Saint Louis Park | Minnesota | 55416 | — |
| Cardiology Associates of North Mississippi | Tupelo | Mississippi | 38801 | — |
| SSM Health DePaul Hospital | Bridgeton | Missouri | 63044 | — |
| Cox Health | Springfield | Missouri | 65807 | — |
| University of Nebraska Medical Center | Omaha | Nebraska | 68106 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601-1915 | — |
| Jersey Shore University Medical Center | Neptune City | New Jersey | 07753 | — |
| Rutgers New Jersey Medical School | Newark | New Jersey | 07103 | — |
| Capital Health Regional Medical Center | Trenton | New Jersey | 08638 | — |
| Mercy Hospital | Buffalo | New York | 14220 | — |
| Jamaica Hospital Medical Center | Jamaica | New York | 11418 | — |
| United Health Services | Johnson City | New York | 13790 | — |
| Lenox Hill Hospital | Lake Success | New York | 11041 | — |
| Long Island Jewish Med Ctr | New Hyde Park | New York | 11040 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Lincoln Hospital | The Bronx | New York | 10451 | — |
| Mission Hospital | Asheville | North Carolina | 28801 | — |
| Novant Health | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Guilford Neurologic Associates | Greensboro | North Carolina | 27405 | — |
| Summa Health System | Akron | Ohio | 44304 | — |
| TriHealth Network | Cincinnati | Ohio | 45220 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| The Ohio State University | Columbus | Ohio | 43210 | — |
| Hightower Clinical | Oklahoma City | Oklahoma | 73102 | — |
| Ascension Medical Group - St. John Clinic Infectious Disease | Tulsa | Oklahoma | 74104 | — |
| Providence Portland Medical Center | Portland | Oregon | 97213 | — |
| Providence St Vincent Medical Center | Portland | Oregon | 97225 | — |
| Oregon Health And Science University | Portland | Oregon | 97239 | — |
| Abington Memorial Hospital | Abington | Pennsylvania | 19001 | — |
| UPMC Hamot | Erie | Pennsylvania | 16550 | — |
| University of Pennsylvania Health System | Philadelphia | Pennsylvania | 19104 | — |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | — |
| Temple University Hospital Jeanes Campus | Philadelphia | Pennsylvania | 19111 | — |
| Temple University Hospital | Philadelphia | Pennsylvania | 19140 | — |
| Einstein Medical Center | Philadelphia | Pennsylvania | 19141 | — |
| Rhode Island Hospital Warren Alpert Medical School Brown University | Providence | Rhode Island | 02905 | — |
| Centennial Medical Center | Nashville | Tennessee | 37203 | — |
| TriStar Skyline Medical Center | Nashville | Tennessee | 37207 | — |
| Saint Thomas Health | Nashville | Tennessee | 37215 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Seton Medical Center | Austin | Texas | 78701 | — |
| Baylor Research Institute | Dallas | Texas | 75204 | — |
| Neurology Consultants of Dallas, PA | Dallas | Texas | 75231 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Houston Methodist Neurological Institute | Houston | Texas | 77030 | — |
| McGovern Medical School UT Physicians Neurosurgery Texas Medical Center | Houston | Texas | 77030 | — |
| Houston Methodist Willowbrook Hospital | Houston | Texas | 77070 | — |
| Emergency Medicine Covenant Medical Center | Lubbock | Texas | 79410 | — |
| Sentara Medical Group | Norfolk | Virginia | 23502 | — |
| Winchester Medical Center | Winchester | Virginia | 22601 | — |
| Providence Regional Medical Center Everett | Everett | Washington | 98201 | — |
| Multiple Sclerosis Center at Evergreen | Kirkland | Washington | 98034 | — |
| Sacred Heart Medical Center | Spokane | Washington | 99204 | — |
| Mayo Clinic Health System | Eau Claire | Wisconsin | 54703 | — |
| Mayo Clinic Health System 1 | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05702034, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05702034 live on ClinicalTrials.gov.