A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia

ClinicalTrials.gov ID: NCT05702645

Public ClinicalTrials.gov record NCT05702645. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 10, 2026, 4:10 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Chronic Health Conditions in Down Syndrome-Associated Acute Leukemia: The Down Syndrome Phenotyping Acute Leukemia Study in Survivors (DS-PALS Survivors)

Study identification

NCT ID: NCT05702645
Recruitment status: Recruiting
Study type: Observational
Phase: Not listed
Lead sponsor: Children's Oncology Group; Network
Enrollment: 330 participants

Conditions and interventions

Conditions

Interventions

Biospecimen Collection Procedure
Clinical Evaluation Other
Neurocognitive Assessment Other
Questionnaire Administration Other
Survey Administration Other

Procedure · Other

Eligibility (public fields only)

Age range: 6 Years to 39 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 29, 2023
Primary completion: Jun 29, 2029
Completion: Jun 29, 2029
Last update posted: May 4, 2026

2023 – 2029

United States locations

U.S. sites: 69
U.S. states: 31
U.S. cities: 61

Facility	City	State	ZIP	Site status
Children's Hospital of Alabama	Birmingham	Alabama	35233	Recruiting
Phoenix Childrens Hospital	Phoenix	Arizona	85016	Recruiting
Valley Children's Hospital	Madera	California	93636	Recruiting
UCSF Benioff Children's Hospital Oakland	Oakland	California	94609	Recruiting
Kaiser Permanente-Oakland	Oakland	California	94611	Recruiting
University of California Davis Comprehensive Cancer Center	Sacramento	California	95817	Recruiting
Rady Children's Hospital - San Diego	San Diego	California	92123	Recruiting
UCSF Medical Center-Mission Bay	San Francisco	California	94158	Recruiting
Yale University	New Haven	Connecticut	06520	Recruiting
Alfred I duPont Hospital for Children	Wilmington	Delaware	19803	Recruiting
Golisano Children's Hospital of Southwest Florida	Fort Myers	Florida	33908	Recruiting
Memorial Regional Hospital/Joe DiMaggio Children's Hospital	Hollywood	Florida	33021	Recruiting
Nemours Children's Clinic-Jacksonville	Jacksonville	Florida	32207	Recruiting
Nemours Children's Hospital	Orlando	Florida	32827	Recruiting
Nemours Children's Clinic - Pensacola	Pensacola	Florida	32504	Recruiting
Saint Joseph's Hospital/Children's Hospital-Tampa	Tampa	Florida	33607	Recruiting
Children's Healthcare of Atlanta - Arthur M Blank Hospital	Atlanta	Georgia	30329	Recruiting
Augusta University Medical Center	Augusta	Georgia	30912	Recruiting
Kapiolani Medical Center for Women and Children	Honolulu	Hawaii	96826	Recruiting
Lurie Children's Hospital-Chicago	Chicago	Illinois	60611	Recruiting
Sinai Hospital of Baltimore	Baltimore	Maryland	21215	Recruiting
C S Mott Children's Hospital	Ann Arbor	Michigan	48109	Recruiting
Children's Hospital of Michigan	Detroit	Michigan	48201	Recruiting
Children's Hospitals and Clinics of Minnesota - Minneapolis	Minneapolis	Minnesota	55404	Recruiting
University of Minnesota/Masonic Cancer Center	Minneapolis	Minnesota	55455	Recruiting
University of Mississippi Medical Center	Jackson	Mississippi	39216	Recruiting
Children's Mercy Hospitals and Clinics	Kansas City	Missouri	64108	Recruiting
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Children's Hospital and Medical Center of Omaha	Omaha	Nebraska	68114	Recruiting
University of Nebraska Medical Center	Omaha	Nebraska	68198	Recruiting
University Medical Center of Southern Nevada	Las Vegas	Nevada	89102	Recruiting
Sunrise Hospital and Medical Center	Las Vegas	Nevada	89109	Recruiting
Alliance for Childhood Diseases/Cure 4 the Kids Foundation	Las Vegas	Nevada	89135	Recruiting
Summerlin Hospital Medical Center	Las Vegas	Nevada	89144	Recruiting
Renown Regional Medical Center	Reno	Nevada	89502	Recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Recruiting
Albany Medical Center	Albany	New York	12208	Recruiting
Roswell Park Cancer Institute	Buffalo	New York	14263	Recruiting
Montefiore Medical Center - Moses Campus	The Bronx	New York	10467	Recruiting
UNC Lineberger Comprehensive Cancer Center	Chapel Hill	North Carolina	27599	Recruiting
Wake Forest University Health Sciences	Winston-Salem	North Carolina	27157	Recruiting
Sanford Broadway Medical Center	Fargo	North Dakota	58122	Recruiting
Children's Hospital Medical Center of Akron	Akron	Ohio	44308	Recruiting
Rainbow Babies and Childrens Hospital	Cleveland	Ohio	44106	Recruiting
Cleveland Clinic Foundation	Cleveland	Ohio	44195	Recruiting
Nationwide Children's Hospital	Columbus	Ohio	43205	Recruiting
Dayton Children's Hospital	Dayton	Ohio	45404	Recruiting
University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	73104	Recruiting
Oregon Health and Science University	Portland	Oregon	97239	Recruiting
Children's Hospital of Philadelphia	Philadelphia	Pennsylvania	19104	Recruiting
Children's Hospital of Pittsburgh of UPMC	Pittsburgh	Pennsylvania	15224	Recruiting
Rhode Island Hospital	Providence	Rhode Island	02903	Recruiting
Prisma Health Richland Hospital	Columbia	South Carolina	29203	Recruiting
BI-LO Charities Children's Cancer Center	Greenville	South Carolina	29605	Recruiting
Sanford USD Medical Center - Sioux Falls	Sioux Falls	South Dakota	57117-5134	Recruiting
East Tennessee Childrens Hospital	Knoxville	Tennessee	37916	Recruiting
Saint Jude Children's Research Hospital	Memphis	Tennessee	38105	Recruiting
Vanderbilt University/Ingram Cancer Center	Nashville	Tennessee	37232	Recruiting
Dell Children's Medical Center of Central Texas	Austin	Texas	78723	Recruiting
UT Southwestern/Simmons Cancer Center-Dallas	Dallas	Texas	75390	Recruiting
Cook Children's Medical Center	Fort Worth	Texas	76104	Recruiting
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center	Houston	Texas	77030	Recruiting
M D Anderson Cancer Center	Houston	Texas	77030	Recruiting
University of Texas Health Science Center at San Antonio	San Antonio	Texas	78229	Recruiting
Seattle Children's Hospital	Seattle	Washington	98105	Recruiting
Providence Sacred Heart Medical Center and Children's Hospital	Spokane	Washington	99204	Recruiting
University of Wisconsin Carbone Cancer Center - University Hospital	Madison	Wisconsin	53792	Recruiting
Marshfield Medical Center-Marshfield	Marshfield	Wisconsin	54449	Recruiting
Children's Hospital of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05702645, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 4, 2026 · Synced May 10, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05702645 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →