ClinicalTrials.gov record
A Study to Evaluate Rocatinlimab (AMG 451) in Adolescent Participants With Moderate-to-severe Atopic Dermatitis (AD)
ClinicalTrials.gov ID: NCT05704738
Public ClinicalTrials.gov record NCT05704738. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, 52-week, Placebo-controlled, Double-blind Study With Re-randomization to Assess the Efficacy, Safety, and Tolerability of Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-ASTRO)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy and safety of rocatinlimab in monotherapy and combination therapy treatment in adolescent participants.
Study identification
- NCT ID
- NCT05704738
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 532 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 20, 2023 (Actual)
- Primary completion
- Feb 27, 2025 (Actual)
- Completion
- Nov 25, 2025 (Actual)
- Last update posted
- Aug 28, 2026
2023 – 2025
United States locations
- U.S. sites
- 98
- U.S. states
- 34
- U.S. cities
- 87
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Cahaba Dermatology and Skin Health Center | Birmingham | Alabama | 35244 | — |
| AllerVie Clinical Research- Cullman | Cullman | Alabama | 35058 | — |
| Eclipse Clinical Research | Tucson | Arizona | 85745 | — |
| Arkansas Research Trials, LLC | North Little Rock | Arkansas | 72117 | — |
| Center for Dermatology Clinical Research Inc | Fremont | California | 94538 | — |
| Doc1 Healthcare Systems Incorporated | Fullerton | California | 92831 | — |
| Axon Clinical Research | Inglewood | California | 90301 | — |
| Avance Clinical Trials | Laguna Niguel | California | 92677 | — |
| Cura Clinical Research | Palmdale | California | 93551 | — |
| Integrative Skin Science and Research | Sacramento | California | 95815 | — |
| University of California at Davis Medical Center | Sacramento | California | 95816 | — |
| Allergy and Asthma Medical Group and Research Center | San Diego | California | 92123 | — |
| University of California at San Diego Rady Childrens Hospital San Diego | San Diego | California | 92123 | — |
| Clinical Science Institute | Santa Monica | California | 90404 | — |
| Cura Clinical Research Sherman Oaks | Sherman Oaks | California | 91403 | — |
| Velocity Clinical Research - Denver | Denver | Colorado | 80209 | — |
| Childrens National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Clinical Research of Brandon | Brandon | Florida | 33511 | — |
| Academic Alliance in Dermatology - Saint Petersburg Office | Clearwater | Florida | 33761 | — |
| Corazon United States of America, LLC doing business as Life Clinical Trials | Coral Springs | Florida | 33071 | — |
| Palm Beach Dermatology Group | Delray Beach | Florida | 33484 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33012 | — |
| Glick Skin Institute | Margate | Florida | 33063 | — |
| Miami Clinical Research | Miami | Florida | 33155 | — |
| ara Professionals Limited Liability Corporation | Miami | Florida | 33176 | — |
| Deluxe Health Care LLC | Miami Lakes | Florida | 33014 | — |
| Savin Medical Group LLC | Miami Lakes | Florida | 33014 | — |
| Angels Clinical Research Institute | Miami Lakes | Florida | 33016 | — |
| Optimal Research Sites, LLC | Orange City | Florida | 32763 | — |
| Clinical Associates of Orlando Limited Liability Company | Orlando | Florida | 32819 | — |
| Clinical Research Investments | Orlando | Florida | 32819 | — |
| University of South Florida | Tampa | Florida | 33612 | — |
| Centricity Research Columbus | Columbus | Georgia | 31904 | — |
| Advanced Medical Research PC | Sandy Springs | Georgia | 30328 | — |
| Divine Dermatology and Aesthetics | Savannah | Georgia | 31419 | — |
| McIntosh Clinic PC | Thomasville | Georgia | 31792 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706-1345 | — |
| Velocity Clinical Research - Boise | Meridian | Idaho | 83642 | — |
| NorthShore University HealthSystem Clinical Trials Center | Skokie | Illinois | 60077 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| Southern Indiana Clinical Trials | New Albany | Indiana | 47150 | — |
| The Indiana Clinical Trials Center PC | Plainfield | Indiana | 46168 | — |
| Equity Medical | Bowling Green | Kentucky | 42104 | — |
| Kentucky Advanced Medical Research LLC | Murray | Kentucky | 42071 | — |
| Industrial Medicine Associates Clinical Research Advanced Dermatology Care | Monroe | Louisiana | 71201 | — |
| Aesthetic and Dermatology Center | Rockville | Maryland | 20850 | — |
| Derm Associates, PC | Rockville | Maryland | 20850 | — |
| Oakland Hills Dermatology | Auburn Hills | Michigan | 48326 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Onyx Clinical Research | Flint | Michigan | 48532 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Saint Louis University | St Louis | Missouri | 63110 | — |
| Somnos Clinical Research | Lincoln | Nebraska | 68505 | — |
| Skin Cancer and Dermatology Institute | Reno | Nevada | 89509 | — |
| Allcutis Research | Portsmouth | New Hampshire | 03801 | — |
| The Dermatology Center of New Jersey | Bridgewater | New Jersey | 08807 | — |
| University of New Mexico | Albuquerque | New Mexico | 87102 | — |
| Ace Clinical Trials | Brooklyn | New York | 11211 | — |
| Empire Dermatology | East Syracuse | New York | 13057 | — |
| Smart Medical Research Inc | Jackson Heights | New York | 11372 | — |
| Forest Hills Dermatology Group | Kew Gardens | New York | 11415 | — |
| Pioneer Clinical Research New York | New York | New York | 10016 | — |
| Cornell University - Weill Cornell Medicine | New York | New York | 10075 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Yeshiva University - Montefiore Medical Center | The Bronx | New York | 10467 | — |
| Duke South Durham | Durham | North Carolina | 27713 | — |
| Optima Research | Boardman | Ohio | 44512 | — |
| Apex Clinical Research Center LLC | Mayfield Heights | Ohio | 44124 | — |
| Epic Medical Research - Oklahoma | Chickasha | Oklahoma | 73018 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Dermatology and Aesthetics of Oklahoma | Oklahoma City | Oklahoma | 73120 | — |
| Dermatology Research Center of Oklahoma, PLLC | Tulsa | Oklahoma | 74132 | — |
| Essential Medical Research LLC | Tulsa | Oklahoma | 74137 | — |
| Velocity Clinical Research - Grants Pass | Grants Pass | Oregon | 97527 | — |
| Oregon Health and Science University | Portland | Oregon | 97239 | — |
| Paddington Testing Company Inc | Philadelphia | Pennsylvania | 19103 | — |
| Rhode Island Hospital, Lifespan | Providence | Rhode Island | 02903 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| National Allergy and Asthma Research, LLC | North Charleston | South Carolina | 29420 | — |
| Coastal Pediatric Research | Summerville | South Carolina | 29486 | — |
| HealthStar Physicians Dermatology | Morristown | Tennessee | 37813 | — |
| The University of Texas Health Science Center at Houston | Bellaire | Texas | 77401 | — |
| US Dermatology Partners Cedar Park | Cedar Park | Texas | 78613 | — |
| Studies in Dermatology LLC | Cypress | Texas | 77429 | — |
| MedCare Pharma - Houston | Houston | Texas | 77037 | — |
| Tranquil Clinical Research | Houston | Texas | 77098 | — |
| Sante Clinical Research | Kerrville | Texas | 78028 | — |
| Long and Harris Dermatology | Lubbock | Texas | 79424 | — |
| Sms Clinical Research Limited Liability Company | Mesquite | Texas | 75149 | — |
| Sienna Dermatology Research | Missouri City | Texas | 77459 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Epiphany Dermatology | Southlake | Texas | 76092 | — |
| Pioneer Research Solutions | Sugar Land | Texas | 77479 | — |
| Tanner Clinic | Murray | Utah | 84107 | — |
| Dermatology Research of Utah, dba Providence Dermatology | Providence | Utah | 84332 | — |
| Jordan Valley Dermatology Center | South Jordan | Utah | 84095 | — |
| Maria M Ona MD PC | Franklin | Virginia | 23851 | — |
| Northwest Clinical Research Center | Bellevue | Washington | 98007 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 148 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05704738, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 28, 2026 · Synced Oct 16, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05704738 live on ClinicalTrials.gov.