A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism
Public ClinicalTrials.gov record NCT05712421. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Dose-Conversion Study to Evaluate the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Subjects With Primary Hypothyroidism Who Are Euthyroid on Levothyroxine Replacement Therapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The North Star study is a multi-center, Phase 2, double-blind, randomized, parallel group clinical study to evaluate the safe and effective dose conversion from Levothyroxine to North Star therapy.
Study identification
- NCT ID
- NCT05712421
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 303 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 28, 2023 (Actual)
- Primary completion
- May 5, 2025 (Actual)
- Completion
- Sep 18, 2025 (Actual)
- Last update posted
- Feb 18, 2026
2023 – 2025
United States locations
- U.S. sites
- 31
- U.S. states
- 11
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neuvosyn Investigational Site | Birmingham | Alabama | 35209 | — |
| Neuvosyn Investigational Site | Canoga Park | California | 91304 | — |
| Neuvosyn Investigational Site | Greenbrae | California | 94904 | — |
| Neuvosyn Investigational Site | Toluca Lake | California | 91602 | — |
| Neuvosyn Investigational Site | Farmington | Connecticut | 06030 | — |
| Neuvosyn Investigational Site | Boca Raton | Florida | 33434 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33144 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33145 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33155 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33174 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33179 | — |
| Neuvosyn Investigational Site | Sunrise | Florida | 33351 | — |
| Neuvosyn Investigational Site | Acworth | Georgia | 30101 | — |
| Neuvosyn Investigational Site | Atlanta | Georgia | 30318 | — |
| Neuvosyn Investigational Site | Columbus | Georgia | 31904 | — |
| Neuvosyn Investigational Site | Sugar Hill | Georgia | 30024 | — |
| Neuvosyn Investigational Site | Saginaw | Michigan | 48602 | — |
| Neuvosyn Investigational Site | Gladstone | Missouri | 64118 | — |
| Neuvosyn Investigational Site | Williamsville | New York | 14221 | — |
| Neuvosyn Investigational Site | Denver | North Carolina | 28037 | — |
| Neuvosyn Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Neuvosyn Investigational Site | Beavercreek | Ohio | 45440 | — |
| Neuvosyn Investigational Site | Columbus | Ohio | 31904 | — |
| Neuvosyn Investigational Site | Georgetown | Texas | 78628 | — |
| Neuvosyn Investigational Site | Houston | Texas | 77040 | — |
| Neuvosyn Investigational Site | Katy | Texas | 77450 | — |
| Neuvosyn Investigational Site | Katy | Texas | 77494 | — |
| Neuvosyn Investigational Site | Lewisville | Texas | 75067 | — |
| Neuvosyn Investigational Site | Paris | Texas | 75462 | — |
| Neuvosyn Investigational Site | Pearland | Texas | 77584 | — |
| Neuvosyn Investigational Site | Stafford | Texas | 77477 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05712421, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 18, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05712421 live on ClinicalTrials.gov.