A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism
Public ClinicalTrials.gov record NCT05712421. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Dose-Conversion Study to Evaluate the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Subjects With Primary Hypothyroidism Who Are Euthyroid on Levothyroxine Replacement Therapy
Study identification
- NCT ID
- NCT05712421
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Neuvosyn Laboratories, LLC
- Industry
- Enrollment
- 303 participants
Conditions and interventions
Conditions
Interventions
- Levothyroxine Drug
- North Star Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 27, 2023
- Primary completion
- May 4, 2025
- Completion
- Sep 17, 2025
- Last update posted
- Feb 17, 2026
2023 – 2025
United States locations
- U.S. sites
- 31
- U.S. states
- 11
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neuvosyn Investigational Site | Birmingham | Alabama | 35209 | — |
| Neuvosyn Investigational Site | Canoga Park | California | 91304 | — |
| Neuvosyn Investigational Site | Greenbrae | California | 94904 | — |
| Neuvosyn Investigational Site | Toluca Lake | California | 91602 | — |
| Neuvosyn Investigational Site | Farmington | Connecticut | 06030 | — |
| Neuvosyn Investigational Site | Boca Raton | Florida | 33434 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33144 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33145 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33155 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33174 | — |
| Neuvosyn Investigational Site | Miami | Florida | 33179 | — |
| Neuvosyn Investigational Site | Sunrise | Florida | 33351 | — |
| Neuvosyn Investigational Site | Acworth | Georgia | 30101 | — |
| Neuvosyn Investigational Site | Atlanta | Georgia | 30318 | — |
| Neuvosyn Investigational Site | Columbus | Georgia | 31904 | — |
| Neuvosyn Investigational Site | Sugar Hill | Georgia | 30024 | — |
| Neuvosyn Investigational Site | Saginaw | Michigan | 48602 | — |
| Neuvosyn Investigational Site | Gladstone | Missouri | 64118 | — |
| Neuvosyn Investigational Site | Williamsville | New York | 14221 | — |
| Neuvosyn Investigational Site | Denver | North Carolina | 28037 | — |
| Neuvosyn Investigational Site | Winston-Salem | North Carolina | 27103 | — |
| Neuvosyn Investigational Site | Beavercreek | Ohio | 45440 | — |
| Neuvosyn Investigational Site | Columbus | Ohio | 31904 | — |
| Neuvosyn Investigational Site | Georgetown | Texas | 78628 | — |
| Neuvosyn Investigational Site | Houston | Texas | 77040 | — |
| Neuvosyn Investigational Site | Katy | Texas | 77450 | — |
| Neuvosyn Investigational Site | Katy | Texas | 77494 | — |
| Neuvosyn Investigational Site | Lewisville | Texas | 75067 | — |
| Neuvosyn Investigational Site | Paris | Texas | 75462 | — |
| Neuvosyn Investigational Site | Pearland | Texas | 77584 | — |
| Neuvosyn Investigational Site | Stafford | Texas | 77477 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05712421, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 17, 2026 · Synced May 17, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05712421 live on ClinicalTrials.gov.