A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED (Study in UC for Clinical Efficacy Evaluation of Dupilumab))
Public ClinicalTrials.gov record NCT05731128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multi-center, Randomized, Double-blind, Placebo-controlled Parallel-group Study to Evaluate the Efficacy and Safety of Dupilumab Therapy in Patients With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype
Study identification
- NCT ID
- NCT05731128
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 68 participants
Conditions and interventions
Conditions
Interventions
- Dupilumab Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 11, 2023
- Primary completion
- May 12, 2026
- Completion
- Feb 21, 2027
- Last update posted
- Jun 22, 2026
2023 – 2027
United States locations
- U.S. sites
- 27
- U.S. states
- 9
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Om Research- Site Number : 8400029 | Apple Valley | California | 92307 | — |
| TLC Clinical Research- Site Number : 8400020 | Beverly Hills | California | 90211 | — |
| Om Research - Oxnard- Site Number : 8400028 | Oxnard | California | 93036 | — |
| Palmtree Clinical Research- Site Number : 8400048 | Palm Springs | California | 92262 | — |
| Clinical Trials Management Services - Thousand Oaks- Site Number : 8400034 | Thousand Oaks | California | 91360 | — |
| Homestead Associates in Research- Site Number : 8400004 | Homestead | Florida | 33033 | — |
| Wellness Clinical Research - Miami Lakes - 8181 Northwest 154th Street- Site Number : 8400009 | Miami Lakes | Florida | 33016 | — |
| GI Pros- Site Number : 8400046 | Naples | Florida | 34102 | — |
| Advanced Research Institute - New Port Richey- Site Number : 8400026 | New Port Richey | Florida | 34653 | — |
| Digestive Disease Consultants - Orange Park- Site Number : 8400042 | Orange Park | Florida | 32073 | — |
| Tellabio International Research Services- Site Number : 8400041 | Pembroke Pines | Florida | 33025 | — |
| GCP Clinical Research- Site Number : 8400014 | Tampa | Florida | 33609 | — |
| Gastroenterology Consultants - Roswell- Site Number : 8400022 | Roswell | Georgia | 30076 | — |
| Sanmora Bespoke Clinical Research Solutions- Site Number : 8400043 | East Orange | New Jersey | 07018 | — |
| Smart Medical Research - New York- Site Number : 8400037 | Jackson Heights | New York | 11372 | — |
| DiGiovanna Family Care- Site Number : 8400006 | Massapequa | New York | 11758 | — |
| Tryon Medical Partners - Charlotte - Piedmont Row Drive South- Site Number : 8400008 | Charlotte | North Carolina | 28287 | — |
| Care Access - Lumberton- Site Number : 8400018 | Lumberton | North Carolina | 28358 | — |
| UPMC Presbyterian- Site Number : 8400038 | Pittsburgh | Pennsylvania | 15213 | — |
| Advanced Gastroenterology Associates - Decatur- Site Number : 8400047 | Decatur | Texas | 76234 | — |
| Katy Integrative Gastroenterology- Site Number : 8400027 | Katy | Texas | 77494 | — |
| Medrasa Clinical Research - Medrasa Sherman- Site Number : 8400039 | Sherman | Texas | 75092 | — |
| Texas Digestive Disease Consultants - Southlake- Site Number : 8400013 | Southlake | Texas | 76092 | — |
| Digestive Health Specialists of Tyler- Site Number : 8400031 | Tyler | Texas | 75701 | — |
| Victoria Gastroenterology- Site Number : 8400019 | Victoria | Texas | 77904 | — |
| Washington Gastroenterology - Bellevue- Site Number : 8400025 | Bellevue | Washington | 98004 | — |
| Washington Gastroenterology - Tacoma- Site Number : 8400030 | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05731128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2026 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05731128 live on ClinicalTrials.gov.