Study of BMF-219 in Healthy Adult Subjects and in Adult Subjects With Type 2 Diabetes Mellitus (T2D)
Public ClinicalTrials.gov record NCT05731544. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, PK, and PD of BMF-219, an Oral Covalent Menin Inhibitor, in Healthy Adults and Adults With T2D
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A Phase 1/ 2 Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMF-219, an Oral Covalent Menin Inhibitor, in Healthy Adult Subjects and in Adult Subjects with Type 2 Diabetes Mellitus.
Study identification
- NCT ID
- NCT05731544
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 443 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 17, 2022 (Actual)
- Primary completion
- Nov 18, 2024 (Actual)
- Completion
- Jul 8, 2025 (Actual)
- Last update posted
- Nov 10, 2025
2022 – 2025
United States locations
- U.S. sites
- 36
- U.S. states
- 13
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Hope Clinical Research | Canoga Park | California | 91303 | — |
| Ark Clinical Research, LLC | Fountain Valley | California | 92708 | — |
| Velocity Clinical Research | La Mesa | California | 91942 | — |
| Ark Clinical Research | Long Beach | California | 90815 | — |
| Catalina Research Institute, LLC | Montclair | California | 91763 | — |
| Metro Clinical Trials | San Bernardino | California | 92404 | — |
| Southwest General Healthcare Center | Fort Myers | Florida | 33907 | — |
| G+C Research Group | Hialeah | Florida | 33010 | — |
| Sunbright Health Research Centers | Homestead | Florida | 33032 | — |
| Avantis Clinical Research | Miami | Florida | 33155 | — |
| Century Research LLC | Miami | Florida | 33173 | — |
| Entrust Clinical Research | Miami | Florida | 33176 | — |
| Panax Clinical Research | Miami Lakes | Florida | 33014 | — |
| David Kavtaradze MD, Inc | Cordele | Georgia | 31015 | — |
| Privia Medical Group | Savannah | Georgia | 31406 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607 | — |
| IMA Clinical Research St. Louis | St Louis | Missouri | 63117 | — |
| Santa Rosa Medical Centers of Nevada | Las Vegas | Nevada | 89119 | — |
| Omera Health | Brooklyn | New York | 11220 | — |
| IMA Clinical Research Manhattan | New York | New York | 10036 | — |
| Carolina Research Center | Shelby | North Carolina | 28150 | — |
| Wake Forest Health Network, LLC, Medical Plaza | Winston-Salem | North Carolina | 27104 | — |
| Diabetes and Endocrinology Associates of Stark County | Canton | Ohio | 44718 | — |
| Medical Care, LLC | Elizabethton | Tennessee | 37643 | — |
| IMA Clinical Research | Austin | Texas | 78745 | — |
| Velocity Clinical Research | Dallas | Texas | 75230 | — |
| Zenos Clinical Research | Dallas | Texas | 75230 | — |
| Synergy Groups Medical LLC | Houston | Texas | 77036 | — |
| Synergy Group Medical | Houston | Texas | 77061 | — |
| Synergy Group Medical | Missouri City | Texas | 77459 | — |
| Clinical Trials of Texas, LLC | San Antonio | Texas | 78229 | — |
| Diabetes & Glandular Disease Clinic, P.A. | San Antonio | Texas | 78229 | — |
| Simcare Medical Research | Sugar Land | Texas | 77478 | — |
| Velocity Clinical Research | Waco | Texas | 76710 | — |
| Velocity Clinical Research | Jordan | Utah | 84088 | — |
| Manassas Clinical Research | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05731544, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 10, 2025 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05731544 live on ClinicalTrials.gov.