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Completed Phase 3 Interventional Results available

ACTIV-6: COVID-19 Study of Repurposed Medications - Arm C (Fluticasone)

ClinicalTrials.gov ID: NCT05736874

Public ClinicalTrials.gov record NCT05736874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 18, 2026, 3:33 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

ACTIV-6: COVID-19 Outpatient Randomized Trial to Evaluate Efficacy of Repurposed Medications

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the effectiveness of repurposed medications (study drug(s) in reducing symptoms of non-hospitalized participants with mild to moderate COVID-19. Participants will receive either study drug or placebo. They will self-report any new or worsening symptoms or medical events they may experience while taking study drug or placebo. This study is intended to be all remote with no in person visits, unless the study team feels it is in the best interest of a participant to see them in person. Prior and current drug arms are listed on clinicaltrials.gov and will be updated with the activation of any new drug arms. This protocol was originally registered under NCT04885530. Per recent guidance on reporting master protocol research programs (MPRPs), a separate record for Arm C was created.

Study identification

NCT ID
NCT05736874
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Susanna Naggie, MD
Other
Enrollment
1,407 participants

Conditions and interventions

Conditions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
30 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 6, 2021 (Actual)
Primary completion
Mar 17, 2022 (Actual)
Completion
May 18, 2022 (Actual)
Last update posted
Jun 18, 2023

2021 – 2022

United States locations

U.S. sites
87
U.S. states
28
U.S. cities
78
Facility City State ZIP Site status
Lamb Health, LLC Gilbert Arizona 85298 —
First Care Medical Clinic Mesa Arizona 85203 —
Trident Health Center Peoria Arizona 85382 —
Hoag Memorial Hospital Presbyterian Newport Beach California 92663 —
Assuta Family Medical Group APMC North Hollywood California 91606 —
Stanford Palo Alto California 94304 —
Doctors Medical Group of Colorado Springs, P.C. Colorado Springs Colorado 80917 —
Pine Ridge Family Medicine Inc. Colorado Springs Colorado 80924 —
Tabitha B. Fortt, M.D., LLC Stamford Connecticut 06905 —
George Washington University Hospital Washington D.C. District of Columbia 20037 —
Lupus Foundation of Gainesville Gainesville Florida 32606 —
University of Florida Health Gainesville Florida 32611 —
University of Florida-JAX-ASCENT Jacksonville Florida 32209 —
AMRON Vitality and Wellness Center, LLC Jacksonville Florida 32244 —
Sunshine Walk In Clinic Lake Mary Florida 32746 —
Lakeland Regional Medical Center Lakeland Florida 33805 —
Jackson Memorial Hospital Miami Florida 33136 —
University of Miami Miami Florida 33136 —
Well Pharma Medical Research Miami Florida 33173 —
Innovation Clinical Trials Inc. Palmetto Bay Florida 33157 —
Lice Source Services Plantation Plantation Florida 33313 —
Premier Health St. Petersburg Florida 33707 —
Tallahassee Memorial Hospital Tallahassee Florida 32308 —
Tampa General Hospital Tampa Florida 33606 —
UF Health Precision Health Research The Villages Florida 32159 —
Emory Healthcare Atlanta Georgia 30322 —
Essential Medical Care, Inc. College Park Georgia 30349 —
David Kavtaradze MD, Inc. Cordele Georgia 31015 —
Elite Family Practice Douglasville Georgia 30134 —
Christ the King Health Care, P.C. Loganville Georgia 30052 —
Miller Family Practice, LLC Macon Georgia 31201 —
Olivo Wellness Medical Center Chicago Illinois 60618 —
NorthShore Medical Group Evanston Illinois 60201 —
Advanced Medical Care, Ltd Lake Zurich Illinois 60047 —
Franciscan Health Michigan City Michigan City Indiana 46360 —
Del Pilar Medical and Urgent Care Mishawaka Indiana 46545 —
University of Kansas - Wichita Wichita Kansas 67214 —
A New Start II, LLC Central City Kentucky 42330 —
University Medical Center- New Orleans New Orleans Louisiana 70112 —
Ochsner Clinic Foundation New Orleans Louisiana 70121 —
Johns Hopkins Hospital Baltimore Maryland 21287-1900 —
Jadestone Clinical Research, LLC Rockville Maryland 20855 —
Boston Medical Center Boston Massachusetts 02118 —
Health Quality Primary Care Lawrence Massachusetts 01843 —
Ananda Medical Clinic Dearborn Michigan 48124 —
GFC of Southeastern Michigan, PC Detroit Michigan 48202 —
Romancare Health Services Detroit Michigan 48206 —
Essentia Health Duluth Minnesota 55805 —
University of Minnesota Minneapolis Minnesota 55455 —
University of Missouri - Columbia Columbia Missouri 65212 —
Comprehensive Pain Management and Endocrinology Henderson Nevada 89052 —
Focus Clinical Research Solutions Bayonne New Jersey 07002 —
Raritan Bay Primary Care & Cardiology Associates Matawan New Jersey 07747 —
Mediversity Healthcare Turnersville New Jersey 08012 —
Geriatrics and Medical Associates Clinton New York 13323 —
Weill Cornell Medical College New York New York 10065 —
Spinal Pain and Medical Rehab, PC Yonkers New York 10701 —
Vaidya MD PLLC Clayton North Carolina 27520 —
Maria Medical Center, PLLC Dunn North Carolina 28334 —
Duke Clinical Research Institute Durham North Carolina 27701 —
Duke University Medical Center Durham North Carolina 27710 —
Wake Forest Baptist Health Winston-Salem North Carolina 27151 —
Diabetes and Endocrinology Assoc. of Stark County Canton Ohio 44718 —
University of Cincinnati Cincinnati Ohio 45267 —
TriHealth, Inc Montgomery Ohio 45242 —
The Heart and Medical Center Durant Oklahoma 74701 —
Hugo Medical clinic Hugo Oklahoma 74743 —
Bucks County Clinical Research Morrisville Pennsylvania 19067 —
Temple University Hospital Philadelphia Pennsylvania 19140 —
University of Pittsburgh Pittsburgh Pennsylvania 15213 —
Medical University of South Carolina Charleston South Carolina 29403 —
Clinical Trials Center of Middle TN Franklin Tennessee 37067 —
Rapha Family Wellness Hendersonville Tennessee 37075 —
Medical Specialists of Knoxville Knoxville Tennessee 37938 —
Vanderbilt University Medical Center Nashville Tennessee 37203 —
Express Family Clinic Allen Texas 75013 —
Texas Tech University Health Sciences Center El Paso Texas 79905 —
Texas Health Physicians Group Fort Worth Texas 76107 —
Highlands Medical Associates, P.A. Highlands Texas 77562 —
University of Texas Health Science Center at Houston Houston Texas 77030 —
Family Practice Doctors P.A. Humble Texas 77338 —
Vytalus Medical Group Humble Texas 77338 —
Texas Health Physicians Group Irving Texas 75039 —
University Diagnostics and Treatment Clinic Pasadena Texas 77504 —
University of Texas Health Science Center at San Antonio San Antonio Texas 78229 —
Jeremy W. Szeto, D.O., P.A. Sugar Land Texas 77479 —
University of Virginia Charlottesville Virginia 22903 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05736874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jun 18, 2023 · Synced Oct 18, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05736874 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →