ClinicalTrials.gov record
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
ClinicalTrials.gov ID: NCT05739383
Public ClinicalTrials.gov record NCT05739383. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 21, 2026, 1:01 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Multicenter Study to Evaluate the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events in High-risk Primary Prevention Patients (VICTORION-1 PREVENT)
Study identification
- NCT ID
- NCT05739383
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 14,012 participants
Conditions and interventions
Interventions
- Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL Drug
- Placebo in 1.5ml Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years to 79 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 8, 2023
- Primary completion
- Apr 15, 2029
- Completion
- Apr 15, 2029
- Last update posted
- Apr 13, 2026
2023 – 2029
United States locations
- U.S. sites
- 243
- U.S. states
- 42
- U.S. cities
- 192
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Central Alabama Research | Birmingham | Alabama | 35209 | — |
| UAB St Vincents | Birmingham | Alabama | 35211 | — |
| Eastern Shore Research Institute | Fairhope | Alabama | 36532 | — |
| G and L Research LLC | Foley | Alabama | 36535 | — |
| Longwood Research | Huntsville | Alabama | 35801 | — |
| CB Flock Corporation | Mobile | Alabama | 36608 | — |
| Mobile Heart Specialists | Mobile | Alabama | 36608 | — |
| The Center for Clinical Trials | Saraland | Alabama | 36571 | — |
| Synexus | Glendale | Arizona | 85306 | — |
| Lenzmeier Family Practice | Glendale | Arizona | 85308 | — |
| Clinical Research Inst of Arizona | Sun City West | Arizona | 85375 | — |
| Clinical Research Advantage Fiel Family and Sports Med, PC | Tempe | Arizona | 85283 | — |
| Synexus Clinical Research US Inc | Tucson | Arizona | 85741 | — |
| Cardiovascular Res Found | Beverly Hills | California | 90210 | — |
| National Heart Institute | Beverly Hills | California | 90211 | — |
| Alliance Clinical | Canoga Park | California | 91303 | — |
| Inland Psychiatric Medical Group | Chino | California | 91710 | — |
| Valley Clinical Trials Inc | Covina | California | 91723 | — |
| Keck Medical Center USC | Los Angeles | California | 90033 | — |
| Charles R Drew University of Medicine and Science | Los Angeles | California | 90059 | — |
| C for Endo Diabetes and MD | Newhall | California | 91321 | — |
| California Medical Research Associates Inc | Northridge | California | 91324 | — |
| Valley Clinical Trials | Northridge | California | 91325 | — |
| Stanford University Medical Center | Palo Alto | California | 94304 | — |
| Clinical Trials Research Sacramento | Sacramento | California | 95821-2134 | — |
| Cordova Clinical Research | Sacramento | California | 95841 | — |
| University of California San Diego | San Diego | California | 92103 | — |
| Kaiser Permanente San Diego | San Diego | California | 92108 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Harbor UCLA Medical Center | Torrance | California | 90502 | — |
| Cardiology Associates Medical Group | Ventura | California | 93003 | — |
| Blue Coast Research Center LLC | Vista | California | 92081 | — |
| Interv Cardiology Med Grp | West Hills | California | 91307 | — |
| South Denver Cardiology Associates PC | Littleton | Colorado | 80120 | — |
| Cardiology Ass of Fairfield County | Stamford | Connecticut | 06905 | — |
| Chase Medical Research LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials LLC | Boca Raton | Florida | 33434 | — |
| Nova Clinical Research LLC | Bradenton | Florida | 34209 | — |
| Bay Care Medical Group | Clearwater | Florida | 33756 | — |
| Clearwater Cardiovascular and Interventional Consultants | Clearwater | Florida | 33756 | — |
| Tampa Bay Medical Research | Clearwater | Florida | 33761 | — |
| Cardiology Research Associates | Daytona Beach | Florida | 32117 | — |
| Hillcrest Medical Research | DeLand | Florida | 32720 | — |
| Personal Physicians Care | Delray Beach | Florida | 33445 | — |
| Fleming Island Ctr Clinical Res. | Fleming Island | Florida | 32003 | — |
| Proactive Clinical Research | Fort Lauderdale | Florida | 33308 | — |
| Qway Research | Hialeah | Florida | 33010 | — |
| Indago Research and Health Ctr Inc | Hialeah | Florida | 33012 | — |
| Sister Life Research Inc | Hialeah | Florida | 33013 | — |
| Center for Diabetes and Endocrine Care | Hollywood | Florida | 33021 | — |
| South Florida Rsrch Solutions LLC | Hollywood | Florida | 33021 | — |
| Zenith Clinical Research | Hollywood | Florida | 33021 | — |
| Encore Medical Research | Hollywood | Florida | 33024 | — |
| UF Health Science Center | Jacksonville | Florida | 32209 | — |
| East Coast Institute for Research | Jacksonville | Florida | 32216 | — |
| Columbus Clinical Services LLC | Miami | Florida | 33125 | — |
| Finlay Medical Research | Miami | Florida | 33126 | — |
| Infinite Clinical Research | Miami | Florida | 33133 | — |
| Springs Medical And Research | Miami | Florida | 33135 | — |
| L and C Professional Medical Institute | Miami | Florida | 33144 | — |
| Regenerate Clinical Trial | Miami | Florida | 33155 | — |
| International Research Associates, LLC | Miami | Florida | 33156 | — |
| A&A Research Group Inc | Miami | Florida | 33186 | — |
| Meridian International Research | Miami Gardens | Florida | 33014 | — |
| Inpatient Research Clinical LLC | Miami Lakes | Florida | 33014 | — |
| RM Medical Research Inc | Miami Lakes | Florida | 33014 | — |
| FXM Clin Res Miramar LLC | Miramar | Florida | 33027 | — |
| Advent Health Orlando | Orlando | Florida | 32803 | — |
| CTMD Research | Palm Springs | Florida | 33406 | — |
| DBC Research USA | Pembroke Pines | Florida | 33029 | — |
| Fam Medical Specialists Of Fl Plc | Plant City | Florida | 33563 | — |
| St Johns Center | Ponte Vedra | Florida | 32801 | — |
| Peace River Cardiovascular Center | Port Charlotte | Florida | 33952 | — |
| East Coast Inst for Research LLC | Saint Augustine | Florida | 32086 | — |
| Cardiovascular Center Of Sarasota | Sarasota | Florida | 34239 | — |
| Advanced Medical Research Center | St. Petersburg | Florida | 33713 | — |
| James A Haley Veterans Hospital | Tampa | Florida | 33612 | — |
| BayCare Health System | Tampa | Florida | 33705 | — |
| Cardiology Partners Clinical Research Institute | Wellington | Florida | 33449 | — |
| East Coast Research | Canton | Georgia | 30114 | — |
| Javara Research | Fayetteville | Georgia | 30214 | — |
| The Jones Center For Diabetes And Endocrine Wellness | Macon | Georgia | 31210 | — |
| Atlanta Heart Specialists LLC | Tucker | Georgia | 30084 | — |
| East West Research Institute | Honolulu | Hawaii | 96814 | — |
| Kootenai Heart Clinic-Sandpoint | Sandpoint | Idaho | 83864 | — |
| Endeavor Health Clinical Op- NCH | Arlington Heights | Illinois | 60005 | — |
| Chicago Clinical Research Inst | Chicago | Illinois | 60607 | — |
| University of Illinois at Chicago | Chicago | Illinois | 60612 | — |
| Flourish Research | Grandwood Park | Illinois | 60031 | — |
| Cardiovascular Services | Peoria | Illinois | 61602 | — |
| Beacon Health System | Elkhart | Indiana | 46514 | — |
| Franciscan Health Services Research Center | Indianapolis | Indiana | 46237 | — |
| Buynak Clinical Research PC | Valparaiso | Indiana | 46383 | — |
| West Broadway Clinic | Council Bluffs | Iowa | 51501 | — |
| Hutchinson Clinic | Hutchinson | Kansas | 67502 | — |
| Cotton O Neil Clinical Res Center | Topeka | Kansas | 66606 | — |
| Kansas Heart Hospital | Wichita | Kansas | 67226 | — |
| Graves Gilbert Clinic | Bowling Green | Kentucky | 42101 | — |
| The Research Group | Lexington | Kentucky | 40503 | — |
| Research Integrity LLC | Owensboro | Kentucky | 42303 | — |
| Cardiovascular Associates Research | Covington | Louisiana | 70433 | — |
| Louisiana Heart Center Research | Covington | Louisiana | 70433 | — |
| Avant Research Associates LLC | Crowley | Louisiana | 70526 | — |
| North Shore Heart and Vascular | Mandeville | Louisiana | 70448 | — |
| Bethesda Medical Clinic | Marrero | Louisiana | 70072 | — |
| NOLA Care Clinical Research | Metairie | Louisiana | 70006 | — |
| Omega Clinical Research | Metairie | Louisiana | 70006 | — |
| CV Ins of the South | Opelousas | Louisiana | 70570 | — |
| Cardiovascular Solutions LLC | Shreveport | Louisiana | 71103 | — |
| Louisiana Heart Center Research | Slidell | Louisiana | 70458 | — |
| Monroe Research Llc | West Monroe | Louisiana | 71291 | — |
| Southern Clinical Research | Zachary | Louisiana | 70791 | — |
| Northeast Cardiology Associates | Bangor | Maine | 04401 | — |
| Ascension Saint Agnes Heart Care | Baltimore | Maryland | 21229 | — |
| Metropolitan Cardiovascular Consultants Llc | Beltsville | Maryland | 20705 | — |
| Johns Hopkins University | Columbia | Maryland | 21044 | — |
| Anderson Medical Research | Ft. Washington | Maryland | 20744 | — |
| Capitol Cardiology Associates | Lanham | Maryland | 20706 | — |
| MGH | Boston | Massachusetts | 02114 2696 | — |
| Umass Memorial Medical Center | Worcester | Massachusetts | 01655 | — |
| Henry Ford Hospital | Detroit | Michigan | 48202 | — |
| AA Medical Research Center | Flint | Michigan | 48504 | — |
| MyMichigan Medical Center Midland | Midland | Michigan | 48670 | — |
| Central Michigan University | Saginaw | Michigan | 48601 | — |
| Troy Internal Medicine Research | Troy | Michigan | 48098 | — |
| Trinity Health Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Essentia Health | Duluth | Minnesota | 55805 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407-3799 | — |
| Synexus Clinical Research US Inc | Richfield | Minnesota | 55432 | — |
| Park Nicollet Institute | Saint Louis Park | Minnesota | 55416 | — |
| Fairview Health Services | Saint Paul | Minnesota | 55103 | — |
| Elite Clinical Research LLC | Jackson | Mississippi | 39202 | — |
| Jackson Heart Clinic | Jackson | Mississippi | 39216 | — |
| VAMC Research-G V Sonny Montgomery Clinic | Jackson | Mississippi | 39216 | — |
| David M Headley Clinic | Port Gibson | Mississippi | 39150 | — |
| Cardiology Associates of North MS | Tupelo | Mississippi | 38801 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Kansas City VA Medical Center | Kansas City | Missouri | 64128 | — |
| Barnes Jewish Hosp-Washington Univ | St Louis | Missouri | 63110 | — |
| St Louis V A Medical Center | St Louis | Missouri | 63125-4181 | — |
| St Louis Heart and Vascular | St Louis | Missouri | 63136 | — |
| Synexus Clinical Research US Inc | St Louis | Missouri | 63141 | — |
| Mercury Street Medical | Butte | Montana | 59701 | — |
| Nebraska Heart Institute | Lincoln | Nebraska | 68510 | — |
| Lincoln Internal Medicine Associates | Lincoln | Nebraska | 68516 | — |
| University of Nebraska Med Center | Omaha | Nebraska | 68198 | — |
| Las Vegas Endocrinology | Henderson | Nevada | 89074 | — |
| AB Clinical Trials | Las Vegas | Nevada | 89119 | — |
| Clinical Research of South Nevada | Las Vegas | Nevada | 89121 | — |
| Advanced Heart Care | Bridgewater | New Jersey | 08807 | — |
| Cardiovas Assoc of Delaware Valley | Elmer | New Jersey | 08318 | — |
| New Jersey Heart | Linden | New Jersey | 07036 | — |
| Albany Medical College | Albany | New York | 12206 | — |
| Capital Cardiology Associates | Albany | New York | 12211 | — |
| New York Presbyterian Queens | Flushing | New York | 11355 | — |
| Mid Hudson Medical Research PLLC | New Windsor | New York | 12553 | — |
| Hudson Valley Urology | Poughkeepsie | New York | 12601 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Clinical Research Advantage | The Bronx | New York | 10468 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| Cary Research Group | Cary | North Carolina | 27511 | — |
| Moses Cone Hospital | Greensboro | North Carolina | 27401 | — |
| Medication Management LLC | Greensboro | North Carolina | 27405 | — |
| IMA Research | Mount Airy | North Carolina | 27030 | — |
| Multispecialty Research Ass Of NC | Raleigh | North Carolina | 27609 | — |
| Accellacare | Statesville | North Carolina | 28625 | — |
| Adv Imaging Prev and Clin Research | Wilmington | North Carolina | 28401 | — |
| Wake Forest University Baptist Medical Center | Winston-Salem | North Carolina | 27157 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58103 | — |
| Altru Health Research Dept. | Grand Forks | North Dakota | 58201 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Synexus Clinical Research US Inc | Cincinnati | Ohio | 45236 | — |
| Synexus Clinical Research | Columbus | Ohio | 43212 | — |
| Primed Clinical Research | Dayton | Ohio | 45429 | — |
| Providence Medical Group | Dayton | Ohio | 45439 | — |
| NexGen Research | Lima | Ohio | 45801 | — |
| Rama Research LLC | Marion | Ohio | 43302 | — |
| Heart House Research Foundation | Springfield | Ohio | 45504 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| South Oklahoma Heart Research LLC | Oklahoma City | Oklahoma | 73135 | — |
| CCT Hatboro Medical Associates | Horsham | Pennsylvania | 19044 | — |
| Capital Area Research LLC | Newport | Pennsylvania | 17074 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Frontier Clinical Research LLC | Smithfield | Pennsylvania | 15478 | — |
| Care Access | Warwick | Rhode Island | 02886 | — |
| Columbia VA Health Care System | Columbia | South Carolina | 29209 | — |
| Bon Secours Medical Group | Greenville | South Carolina | 29607 | — |
| TRIBE Clinical Research | Greer | South Carolina | 29651 | — |
| Trident Cardiology | Ladson | South Carolina | 29465 | — |
| Main Street Physicians Care | Little River | South Carolina | 29566 | — |
| Care Access Rapid City | Rapid City | South Dakota | 57701 | — |
| Monument Health Clinical Research | Rapid City | South Dakota | 57701 | — |
| Wellmont CVA Heart Institute | Greenville | Tennessee | 37745 | — |
| Apex Cardiology Research Associates of Jackson | Jackson | Tennessee | 38301 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| New Phase Research And Development | Knoxville | Tennessee | 37909 | — |
| Accellacare | Knoxville | Tennessee | 37938 | — |
| Cardiovascular Res of Knoxville LLC | Powell | Tennessee | 37849 | — |
| Tennessee Center For Clinical Trials | Tullahoma | Tennessee | 37388 | — |
| Pharma Tex Research | Amarillo | Texas | 79106 | — |
| Amarillo Heart Clin Rsh Inst | Amarillo | Texas | 79124 | — |
| North Hills Medical Research Inc | Bedford | Texas | 76021 | — |
| Clinical Research Solution | Cypress | Texas | 77429 | — |
| VA North Texas Health Care System | Dallas | Texas | 75216 | — |
| Zenos Clinical Research | Dallas | Texas | 75230 | — |
| SW Family Medicine Associates | Dallas | Texas | 75235 | — |
| Doctors Hospital at Renaissance | Edinburg | Texas | 78539 | — |
| David Turbay MD PLLC | El Paso | Texas | 79905 | — |
| Texas Health Physicians Group | Fort Worth | Texas | 76107 | — |
| East Texas Cardiology PA | Houston | Texas | 77002 | — |
| Primecare Medical Group | Houston | Texas | 77024 | — |
| Northwest Houston Cardiology PA | Houston | Texas | 77070 | — |
| MedCare Pharma LLC | Houston | Texas | 77079 | — |
| Dallas Heart and Vascular Consultants PA | Houston | Texas | 77084 | — |
| Texas Cardiology Assocs Of Houston | Kingwood | Texas | 77339 | — |
| Epic Clinical Research | Lewisville | Texas | 75057 | — |
| East Texas Research Associates Inc. | Livingston | Texas | 77351 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Northeast Clinical Research of San Antonio LLC | San Antonio | Texas | 78233 | — |
| Consano Clinical Research LLC | Shavano Park | Texas | 78231 | — |
| Javara Research | Stephenville | Texas | 76401 | — |
| NRG Wellness Center | Sugarland | Texas | 77478 | — |
| Northwest Houston Clinical Research PLLC | Tomball | Texas | 77375 | — |
| Comprehensive Center | Weslaco | Texas | 78596 | — |
| Intermountain Medical Center | Murray | Utah | 84107 | — |
| Diabetes And Endocrine Specialists | Sandy City | Utah | 84093 | — |
| Burke Internal Medicine and Research | Burke | Virginia | 22015 | — |
| Virginia Heart | Falls Church | Virginia | 22042 | — |
| Heart Care Associates P C | Hopewell | Virginia | 23860 | — |
| Carient Heart and Vascular | Manassas | Virginia | 20109 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298-0111 | — |
| Roanoke Heart Institute | Roanoke | Virginia | 24014 | — |
| Centricity Research Suffolk Fam Med | Suffolk | Virginia | 23435 | — |
| MultiCare Ins Research Innovation | Puyallup | Washington | 98372 | — |
| Universal Research Group LLC | Tacoma | Washington | 98405 | — |
| Confluence Health Hospital | Wenatchee | Washington | 98801 | — |
| West Virginia University Hospital | Morgantown | West Virginia | 26506 | — |
| Midwest Endocrinology Associates | Milwaukee | Wisconsin | 53215 | — |
| Cardiovascular Research and Education Foundation, Inc | Wausau | Wisconsin | 54401 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 742 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05739383, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced May 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05739383 live on ClinicalTrials.gov.