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Active, not recruiting Phase 2 Interventional

Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis

ClinicalTrials.gov ID: NCT05739435

Public ClinicalTrials.gov record NCT05739435. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:11 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Patients With Plaque Psoriasis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a multi-center, open-label extension (OLE) study in patients with plaque psoriasis who have completed their participation in a previous plaque psoriasis study of ESK-001.

Study identification

NCT ID
NCT05739435
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Alumis Inc
Industry
Enrollment
165 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jan 17, 2023 (Actual)
Primary completion
Dec 1, 2027 (Estimated)
Completion
Dec 31, 2027 (Estimated)
Last update posted
Jul 28, 2026

2023 – 2027

United States locations

U.S. sites
28
U.S. states
19
U.S. cities
28
Facility City State ZIP Site status
Investigator Site # 1029 Birmingham Alabama 35205 —
Investigator Site #1001 Phoenix Arizona 85032 —
Investigator Site # 1023 Rogers Arkansas 72758 —
Investigator Site #1021 Encinitas California 92024 —
Investigator Site #1018 Los Angeles California 90045 —
Investigator Site #1007 Santa Monica California 90404 —
Investigator Site #1002 Sherman Oaks California 91403 —
Investigator site # 1030 Fort Lauderdale Florida 33308 —
Investigator Site #1025 Hialeah Florida 33012 —
Investigator site # 1028 Miami Florida 33175 —
Investigator Site # 1013 Tampa Florida 33614 —
Investigator Site #1035 Macon Georgia 31217 —
Investigator Site #1043 Sandy Springs Georgia 30328 —
Investigator Site #1005 Rolling Meadows Illinois 60008 —
Investigator Site # 1011 Columbus Indiana 47201 —
Investigator Site #1027 South Bend Indiana 46617 —
Investigator SIte#1036 Overland Park Kansas 66210 —
Investigator Site #1017 Owensboro Kentucky 42301 —
Investigator Site #1026 Rockville Maryland 20850 —
Investigator Site #1010 Clarkston Michigan 48346 —
Investigator Site #1031 New Brighton Minnesota 55112 —
Investigator Site #1033 Norman Oklahoma 73071 —
Investigator Site #1019 Portland Oregon 97223 —
Investigator Site #1022 Philadelphia Pennsylvania 19103 —
Investigator Site # 1012 Rapid City South Dakota 57702 —
Investigator Site #1015 Houston Texas 77056 —
Investigator Site # 1006 San Antonio Texas 78213 —
Investigator Site # 1041 South Jordan Utah 84095 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05739435, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 28, 2026 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05739435 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →