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Terminated Phase 2 Interventional

A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

ClinicalTrials.gov ID: NCT05740007

Public ClinicalTrials.gov record NCT05740007. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 4, 2026, 6:18 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2 Randomized, Double-blind, Placebo-controlled, Adaptive Study to Evaluate the Efficacy, Safety, and Tolerability of 2 Dose Levels of IW-3300 Administered Rectally for 12 Weeks to Treat Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.

Study identification

NCT ID
NCT05740007
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Ironwood Pharmaceuticals, Inc.
Industry
Enrollment
98 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 27, 2023
Primary completion
Jan 22, 2025
Completion
Feb 5, 2025
Last update posted
Feb 27, 2025

2023 – 2025

United States locations

U.S. sites
53
U.S. states
28
U.S. cities
50
Facility City State ZIP Site status
Urology Associates of Mobile Mobile Alabama 33608
Velocity Clinical Research Mobile Alabama 36608
Ironwood Research Center Scottsdale Arizona 85259
Urological Associates of Southern Arizona Tucson Arizona 85715
Arkansas Urology Little Rock Arkansas 72211
Ironwood Research Center Fresno California 93720
American Institute of Research Los Angeles California 90017
Tri Valley Urology Medical Group Murrieta California 92562
UCI Health Orange California 92868
Ironwood Research Center San Diego California 92130
Solano Regional Medical Group Sutter Regional Medical Foundation Vacaville California 95688
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010
Advanced Urology Institute-Daytona Beach Daytona Beach Florida 32114
Valencia Medical and Research Center Miami Florida 33165
Clinical Associates of Orlando Orlando Florida 32801
Altus Research Palm Springs Florida 33406
Precision Clinical Research Sunrise Florida 33351
South Tampa Health Services Tampa Florida 33609
Ironwood Research Center Cartersville Georgia 30120
Leavitt Clinical Research Idaho Falls Idaho 83404
First Urology PSC Jeffersonville Indiana 47130
Clinical Associates Midwest Overland Park Kansas 66214
Wichita Urology - Newton Wichita Kansas 67226
Ochsner Clinic Foundation New Orleans Louisiana 70121
Ochsner LSU Health Shreveport - Regional Urology Shreveport Louisiana 71106
Bay State Clinical Trials Watertown Massachusetts 02472
William Beaumont Hospital Royal Oak Michigan 48073
Michigan Institute of Urology Troy Michigan 48084
Specialty Clinical Research of St. Louis-Objective Health St Louis Missouri 63141
Quality Clinical Research Omaha Nebraska 68114
Ironwood Research Center Hackensack New Jersey 07601
New Mexico Clinical Research and Osteoporosis Center Albuquerque New Mexico 87106
Urological Institute of Northeast New York Albany New York 12208
Accumed Research Associates Garden City New York 11530
The Arthur Smith Institute for Urology - New Hyde Park Location New Hyde Park New York 11042
Columbia University Irving Medical Center New York New York 10032
Ironwood Research Center New York New York 10065
Atrium Health Wake Forest Baptist Medical Center - Urology Winston-Salem North Carolina 27103
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Central Ohio Urology Group Gahanna Ohio 43230
Genesis Healthcare System Zanesville Ohio 43701
MidLantic Urology Bala-Cynwyd Pennsylvania 19004
Center for Pelvic Health and Urogynecology - Tower Health Medical Group Reading Pennsylvania 19611
Ironwood Research Center Charleston South Carolina 29425
Sanford Research Sioux Falls South Dakota 57105
Chattanooga Medical Research Chattanooga Tennessee 37404
New Phase Research & Development Knoxville Tennessee 37909
Houston Metro Urology Houston Texas 77027
Baylor College of Medicine Houston Texas 77096
Advances In Health Inc Pearland Texas 77584
Highland Clinical Research Salt Lake City Utah 84124
The Chronic Pelvic Pain Center Vienna Virginia 22182
Seattle Clinical Research Center Seattle Washington 98105

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05740007, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 27, 2025 · Synced Sep 4, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05740007 live on ClinicalTrials.gov.

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