The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery
Public ClinicalTrials.gov record NCT05740176. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multi-Center, Prospective, Historically Controlled Pivotal Trial Comparing the Safety and Effectiveness of the Synergy Disc to Anterior Cervical Discectomy and Fusion in Patients With Two-Level Symptomatic Cervical Degenerative Disc Disease (DDD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
A multicenter, prospective, non-randomized, historically controlled study. To demonstrate the Synergy Disc is at least as safe and effective as conventional anterior cervical discectomy and fusion (ACDF) to treat cervical degenerative disc disease (DDD) in subjects who are symptomatic at two levels from C3 to C7 are and are unresponsive to conservative management. Patients will be evaluated preoperatively, at the time of surgery, and at 6 weeks, and 3, 6, 12, and 24 months after surgery. Follow-up will continue annually until the last patient reaches 24-month follow-up. The primary analysis will occur at 24 months.
Study identification
- NCT ID
- NCT05740176
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2023
- Primary completion
- Aug 31, 2026
- Completion
- Nov 30, 2026
- Last update posted
- Jul 5, 2026
2023 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 23
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| HonorHealth | Scottsdale | Arizona | 85258 | — |
| Todd Lanman, MD | Beverly Hills | California | 90210 | — |
| DOCS Health Management LLC | Los Angeles | California | 90048 | — |
| Institute of Neuro Innovation | Santa Monica | California | 91304 | — |
| Steamboat Orthopaedic and Spine Institute | Steamboat Springs | Colorado | 80487 | — |
| Brain and Spine Center of South Florida | Delray Beach | Florida | 33445 | — |
| Kennedy-White Orthopaedic Center | Sarasota | Florida | 34232 | — |
| Indiana Spine Group | Carmel | Indiana | 46032 | — |
| Orthopedics Northeast | Fort Wayne | Indiana | 46825 | — |
| Precision Spine and Orthopaedic Associates, PA | Overland Park | Kansas | 66211 | — |
| Bone and Joint Clinic of Baton Rouge | Baton Rouge | Louisiana | 70808 | — |
| Louisiana Spine Institute | Shreveport | Louisiana | 71101 | — |
| Michigan Orthopedic Surgeons | Royal Oak | Michigan | 48073 | — |
| Carolina NeuroSurgery and Spine Associates, PA | Charlotte | North Carolina | 28204 | — |
| M3 Emerging Medical Research | Durham | North Carolina | 27704 | — |
| Pinehurst Surgical Clinic | Pinehurst | North Carolina | 28374 | — |
| Summit Spine | Portland | Oregon | 97225 | — |
| Oregon Spine Care | Tualatin | Oregon | 97062 | — |
| Austin Neurosurgeons | Austin | Texas | 78746 | — |
| DFW Center for Spinal Disorders | Fort Worth | Texas | 76132 | — |
| Texas Spine Care Center | San Antonio | Texas | 78231 | — |
| The Disc Replacement Center | West Jordan | Utah | 84088 | — |
| Atlantic Brain and Spine | Reston | Virginia | 20190 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05740176, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 5, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05740176 live on ClinicalTrials.gov.