Study Comparing Tarlatamab With Standard of Care Chemotherapy in Relapsed Small Cell Lung Cancer
Public ClinicalTrials.gov record NCT05740566. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Open-label, Phase 3 Study of Tarlatamab Compared With Standard of Care in Subjects With Relapsed Small Cell Lung Cancer After Platinum-based First-line Chemotherapy
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main objective is to compare the efficacy of tarlatamab with standard of care (SOC) on prolonging overall survival (OS).
Study identification
- NCT ID
- NCT05740566
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 509 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2023 (Actual)
- Primary completion
- Jan 29, 2025 (Actual)
- Completion
- Mar 26, 2028 (Estimated)
- Last update posted
- Jan 5, 2026
2023 – 2028
United States locations
- U.S. sites
- 25
- U.S. states
- 20
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of South Alabama Mitchell Cancer Institute | Mobile | Alabama | 36604 | — |
| Alaska Oncology and Hematology | Anchorage | Alaska | 99508 | — |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | — |
| University of California Los Angeles | Santa Monica | California | 90404 | — |
| Northwestern University | Chicago | Illinois | 60611 | — |
| University of Illinois Chicago | Chicago | Illinois | 60612 | — |
| Indiana University | Indianapolis | Indiana | 46202 | — |
| University of Iowa | Iowa City | Iowa | 52242 | — |
| Pikeville Medical Center | Pikeville | Kentucky | 41501 | — |
| Our Lady of the Lake Cancer Institute | Baton Rouge | Louisiana | 70808 | — |
| Trinity Health Saint Joseph Mercy Ann Arbor | Ann Arbor | Michigan | 48106 | — |
| University of Minnesota Cancer Center | Minneapolis | Minnesota | 55455 | — |
| University of Missouri Health Care | Columbia | Missouri | 65212 | — |
| Summit Medical Group, Overlook Oncology Center | Summit | New Jersey | 91010 | — |
| New York University Grossman School of Medicine and New York University Langone Hospitals | New York | New York | 10016 | — |
| Perlmutter Cancer Center at New York University Langone Hospital----Long Island | New York | New York | 10016 | — |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10021 | — |
| Northport Veterans Affairs Medical Center | Northport | New York | 11768 | — |
| Sanford Roger Maris Cancer Center | Fargo | North Dakota | 58102 | — |
| Sanford Oncology Clinic and Pharmacy | Sioux Falls | South Dakota | 57104 | — |
| University of Tennessee Medical Center Knoxville | Knoxville | Tennessee | 37920 | — |
| Baptist Cancer Center | Memphis | Tennessee | 38120 | — |
| Virginia Commonwealth University | Richmond | Virginia | 23298 | — |
| Swedish Cancer Institute Medical Oncology | Edmonds | Washington | 98026 | — |
| The Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 198 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05740566, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 5, 2026 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05740566 live on ClinicalTrials.gov.