Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia
Public ClinicalTrials.gov record NCT05745883. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1b Multicenter, Randomized, Double-Blind, Placebo-Controlled Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DISC-0974 in Participants With Non-Dialysis Dependent Chronic Kidney Disease and Anemia
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This Phase 1b study of DISC-0974 will assess the safety, tolerability, pharmacokinetics (PK) and Pharmacodynamics (PD) of DISC-0974 in adult participants with Non-Dialysis Dependent Chronic Kidney Disease and Anemia.
Study identification
- NCT ID
- NCT05745883
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 55 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 4, 2023 (Actual)
- Primary completion
- Oct 9, 2025 (Actual)
- Completion
- Jan 16, 2026 (Actual)
- Last update posted
- Apr 22, 2026
2023 – 2026
United States locations
- U.S. sites
- 13
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCLA Clinical and Translational Research | Los Angeles | California | 90095 | — |
| US Renal Care Inc. | Lone Tree | Colorado | 80124 | — |
| Accel Research | DeLand | Florida | 32720 | — |
| Total Research Group | Miami | Florida | 33126 | — |
| Flourish Research | Winter Park | Florida | 32789 | — |
| Nephrology and Hypertension Specialists, PC-Dalton | Dalton | Georgia | 30720 | — |
| CARE Institute - Boise Kidney | Boise | Idaho | 83706 | — |
| Center for Advanced Kidney Research PLC | Saint Clair Shores | Michigan | 48081 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Clinical Advancement Center, PLLC | San Antonio | Texas | 78212 | — |
| Endeavor Clinical Trials | San Antonio | Texas | 78240 | — |
| Washington Nephrology Associates, LLP | Alexandria | Virginia | 22304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05745883, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced Sep 30, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05745883 live on ClinicalTrials.gov.