ClinicalTrials.gov record
A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Eosinophilic Asthma
ClinicalTrials.gov ID: NCT05748600
Public ClinicalTrials.gov record NCT05748600. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 24 Weeks in Participants With Eosinophilic Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate dexpramipexole as an add-on oral therapy in participants with inadequately controlled eosinophilic asthma to evaluate improvements in lung function, asthma control, and quality of life. In addition, the study will further evaluate the safety and tolerability of dexpramipexole in participants with eosinophilic asthma.
Study identification
- NCT ID
- NCT05748600
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 30, 2023 (Actual)
- Primary completion
- Sep 2025 (Estimated)
- Completion
- Dec 2025 (Estimated)
- Last update posted
- Sep 5, 2025
2023 – 2025
United States locations
- U.S. sites
- 146
- U.S. states
- 30
- U.S. cities
- 126
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 40001-487 | Chandler | Arizona | 85224 | — |
| Research Site 40001-462 | Peoria | Arizona | 85381 | — |
| Research Site 40001-322 | Surprise | Arizona | 85378 | — |
| Research Site 40001-374 | Bakersfield | California | 93301 | — |
| Research Site 40001-227 | Encinitas | California | 92024 | — |
| Research Site 40001-349 | Huntington Beach | California | 92647 | — |
| Research Site 40001-485 | Inglewood | California | 06410 | — |
| Research Site 40001-440 | La Palma | California | 90623 | — |
| Research Site 40001-357 | Lancaster | California | 93534 | — |
| Research Site 40001-089 | Los Angeles | California | 90048 | — |
| Research Site 40001-362 | Mission Viejo | California | 92691 | — |
| Research Site 40001-449 | Napa | California | 94558 | — |
| Research Site 40001-062 | Newport Beach | California | 92660 | — |
| Research Site 40001-043 | Newport Beach | California | 92663 | — |
| Research Site 40001-380 | Redding | California | 96001 | — |
| Research Site 40001-434 | San Diego | California | 92123 | — |
| Research Site 40001-088 | San Jose | California | 95117 | — |
| Research Site 40001-359 | Upland | California | 91756 | — |
| Research Site 40001-003 | West Covina | California | 91790 | — |
| Research Site 40001-419 | Westminster | California | 92683 | — |
| Research Site 40001-425 | Aurora | Colorado | 80014 | — |
| Research Site 40001-353 | Colorado Springs | Colorado | 80907 | — |
| Research Site 40001-385 | Wheat Ridge | Colorado | 80033 | — |
| Research Site 40001-048 | Aventura | Florida | 33180 | — |
| Research Site 40001-005 | Brandon | Florida | 33511 | — |
| Research Site 40001-051 | Brandon | Florida | 33511 | — |
| Research Site 40001-029 | Coral Gables | Florida | 33134 | — |
| Research Site 40001-350 | Gainesville | Florida | 32607 | — |
| Research Site 40001-014 | Greenacres City | Florida | 33467 | — |
| Research Site 40001-054 | Hialeah | Florida | 33012 | — |
| Research Site 40001-067 | Hialeah | Florida | 33016 | — |
| Research Site 40001-020 | Homestead | Florida | 33030 | — |
| Research Site 40001-015 | Kissimmee | Florida | 34744 | — |
| Research Site 40001-002 | Kissimmee | Florida | 34746 | — |
| Research Site 40001-086 | Loxahatchee Groves | Florida | 33470 | — |
| Research Site 40001-318 | Maitland | Florida | 32751 | — |
| Research Site 40001-066 | Miami | Florida | 33126 | — |
| Research Site 40001-001 | Miami | Florida | 33135 | — |
| Research Site 40001-059 | Miami | Florida | 33144 | — |
| Research Site 40001-026 | Miami | Florida | 33155 | — |
| Research Site 40001-288 | Miami | Florida | 33165 | — |
| Research Site 40001-065 | Miami | Florida | 33173 | — |
| Research Site 40001-024 | Miami | Florida | 33184 | — |
| Research Site 40001-338 | Miami Beach | Florida | 33169 | — |
| Research Site 40001-348 | Ocala | Florida | 34471 | — |
| Research Site 40001-293 | Orlando | Florida | 32819 | — |
| Research Site 40001-429 | Plantation | Florida | 33317 | — |
| Research Site 40001-351 | Sarasota | Florida | 34239 | — |
| Research Site 40001-069 | St. Petersburg | Florida | 33713 | — |
| Research Site 40001-370 | Tallahassee | Florida | 32308 | — |
| Research Site 40001-004 | Tampa | Florida | 33607 | — |
| Research Site 40001-319 | Viera | Florida | 32940 | — |
| Research Site 40001-142 | Adairsville | Georgia | 30103 | — |
| Research Site 40001-075 | Augusta | Georgia | 30909 | — |
| Research Site 40001-018 | Columbus | Georgia | 31904 | — |
| Research Site 40001-452 | Dunwoody | Georgia | 30350 | — |
| Research Site 40001-483 | East Point | Georgia | 30344 | — |
| Research Site 40001-366 | Lilburn | Georgia | 30047 | — |
| Research Site 40001-423 | Savannah | Georgia | 31406 | — |
| Research Site 40001-090 | Berwyn | Illinois | 60402 | — |
| Research Site 40001-343 | Chicago | Illinois | 60607 | — |
| Research Site 40001-358 | Normal | Illinois | 61761 | — |
| Research Site 40001-135 | River Forest | Illinois | 60305 | — |
| Research Site 40001-403 | Skokie | Illinois | 60077 | — |
| Research Site 40001-036 | Elwood | Indiana | 46036 | — |
| Research Site 40001-347 | Louisville | Kentucky | 40202 | — |
| Research Site 40001-019 | Owensboro | Kentucky | 42301 | — |
| Research Site 40001-437 | Alexandria | Louisiana | 71303 | — |
| Research Site 40001-313 | Marrero | Louisiana | 70072 | — |
| Research Site 40001-352 | Zachary | Louisiana | 70791 | — |
| Research Site 40001-417 | Annapolis | Maryland | 21401 | — |
| Research Site 40001-466 | Baltimore | Maryland | 21237 | — |
| Research Site 40001-456 | Takoma Park | Maryland | 20912 | — |
| Research Site 40001-055 | White Marsh | Maryland | 21162 | — |
| Research Site 40001-468 | Fall River | Massachusetts | 02723 | — |
| Research Site 40001-427 | Dearborn | Michigan | 48126 | — |
| Research Site 40001-006 | Flint | Michigan | 48504 | — |
| Research Site 40001-148 | Flint | Michigan | 48507 | — |
| Research Site 40001-463 | Rochester Hills | Michigan | 48307 | — |
| Research Site 40001-442 | Southfield | Michigan | 48034 | — |
| Research Site 40001-372 | Warren | Michigan | 48088 | — |
| Research Site 40001-421 | Mankato | Minnesota | 56001 | — |
| Research Site 40001-083 | Columbia | Missouri | 65203 | — |
| Research Site 40001-074 | Saint Charles | Missouri | 63301 | — |
| Research Site 40001-046 | St Louis | Missouri | 63110 | — |
| Research Site 40001-409 | Missoula | Montana | 59808 | — |
| Research Site 40001-448 | Lincoln | Nebraska | 68510 | — |
| Research Site 40001-404 | Omaha | Nebraska | 68798 | — |
| Research Site 40001-473 | Las Vegas | Nevada | 89109 | — |
| Research Site 40001-387 | Brick | New Jersey | 08724 | — |
| Research Site 40001-363 | Edison | New Jersey | 08817 | — |
| Research Site 40001-457 | Jersey City | New Jersey | 07304 | — |
| Research Site 40001-355 | Toms River | New Jersey | 08755 | — |
| Research Site 40001-050 | East Amherst | New York | 14051 | — |
| Research Site 40001-412 | Great Neck | New York | 11021 | — |
| Research Site 40001-047 | Hawthorne | New York | 10532 | — |
| Research Site 40001-455 | New York | New York | 10016 | — |
| Research Site 40001-369 | New York | New York | 10029 | — |
| Research Site 40001-408 | Charlotte | North Carolina | 28273 | — |
| Research Site 40001-398 | Charlotte | North Carolina | 28277 | — |
| Research Site 40001-039 | Gastonia | North Carolina | 28054 | — |
| Research Site 40001-435 | Greenville | North Carolina | 17834 | — |
| Research Site 40001-111 | Huntersville | North Carolina | 28078 | — |
| Research Site 40001-382 | Raleigh | North Carolina | 27610 | — |
| Research Site 40001-439 | Rocky Mount | North Carolina | 27804 | — |
| Research Site 40001-283 | Winston-Salem | North Carolina | 21704 | — |
| Research Site 40001-034 | Cincinnati | Ohio | 45215 | — |
| Research Site 40001-013 | Cincinnati | Ohio | 45219 | — |
| Research Site 40001-010 | Cincinnati | Ohio | 45236 | — |
| Research Site 40001-413 | Cleveland | Ohio | 44106 | — |
| Research Site 40001-017 | Dayton | Ohio | 45424 | — |
| Research Site 40001-063 | Toledo | Ohio | 43617 | — |
| Research Site US-40001-038 | Edmond | Oklahoma | 73034 | — |
| Research Site 40001-386 | Oklahoma City | Oklahoma | 73102 | — |
| Research Site 40001-079 | Oklahoma City | Oklahoma | 73120 | — |
| Research Site 40001-027 | Grants Pass | Oregon | 97527 | — |
| Research Site 40001-337 | Portland | Oregon | 97202 | — |
| Research Site 40001-395 | Hershey | Pennsylvania | 17033 | — |
| Research Site 40001-327 | Philadelphia | Pennsylvania | 19140 | — |
| Research Site 40001-032 | Columbia | South Carolina | 29204 | — |
| Research Site 40001-025 | Greenville | South Carolina | 29651 | — |
| Research Site 40001-430 | Rock Hill | South Carolina | 29732 | — |
| Research Site 40001-073 | Spartanburg | South Carolina | 29303 | — |
| Research Site 40001-438 | Dickson | Tennessee | 37055 | — |
| Research Site 40001-414 | Franklin | Tennessee | 37067 | — |
| Research Site 40001-334 | Allen | Texas | 75013 | — |
| Research Site 40001-068 | Amarillo | Texas | 79124 | — |
| Research Site 40001-023 | Dallas | Texas | 75230 | — |
| Research Site 40001-028 | Dallas | Texas | 75235 | — |
| Research Site 40001-415 | Dallas | Texas | 75246 | — |
| Research Site 40001-304 | DeSoto | Texas | 75115 | — |
| Research Site 40001-418 | Frisco | Texas | 75034 | — |
| Research Site 40001-064 | Houston | Texas | 77074 | — |
| Research Site 40001-085 | Houston | Texas | 77099 | — |
| Research Site 40001-424 | Kerrville | Texas | 78028 | — |
| Research Site 40001-295 | McKinney | Texas | 75069 | — |
| Research Site 40001-304 | Red Oak | Texas | 75154 | — |
| Research Site 40001-377 | San Antonio | Texas | 78258 | — |
| Research Site 40001-335 | Sugar Land | Texas | 77479 | — |
| Research Site 40001-258 | Murray | Utah | 84107 | — |
| Research Site 40001-333 | Pleasant View | Utah | 84404 | — |
| Research Site 40001-340 | Burke | Virginia | 22015 | — |
| Research Site 40001-394 | Williamsburg | Virginia | 23188 | — |
| Research Site 40001-339 | Greenfield | Wisconsin | 53228 | — |
| Research Site 40001-433 | La Crosse | Wisconsin | 54601 | — |
| Research Site 40001-443 | La Crosse | Wisconsin | 54601 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 189 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05748600, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 5, 2025 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05748600 live on ClinicalTrials.gov.