ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Public ClinicalTrials.gov record NCT05749055. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
The ENCALM Trial: A Randomized, Double-blind, Placebo-controlled Monotherapy Trial to Evaluate the Efficacy and Safety of ENX-102 in Patients With Generalized Anxiety Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)
Study identification
- NCT ID
- NCT05749055
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 252 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 3, 2023 (Actual)
- Primary completion
- Sep 18, 2025 (Actual)
- Completion
- Sep 18, 2025 (Actual)
- Last update posted
- Sep 21, 2026
2023 – 2025
United States locations
- U.S. sites
- 32
- U.S. states
- 14
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| IMA Clinical Research Phoenix | Phoenix | Arizona | 85012 | — |
| Collaborative Neuroscience Research, LLC (CNS) | Garden Grove | California | 92845 | — |
| Sun Valley Research Center | Imperial | California | 92251 | — |
| Alliance Research | Long Beach | California | 90712 | — |
| NRC Research Institute | Los Angeles | California | 90015 | — |
| Excell Research, Inc. | Oceanside | California | 92056 | — |
| Anderson Clinical Research | Redlands | California | 92374 | — |
| California Neuroscience Research, LLC | Sherman Oaks | California | 91403 | — |
| Pacific Clinical Research Management Group | Upland | California | 91786 | — |
| Sunwise Clinical Research | Walnut Creek | California | 94596 | — |
| Mountain View Clinical Research | Denver | Colorado | 80209 | — |
| Vertex Clinical Research | Clermont | Florida | 34711 | — |
| Clinical Neuroscience Solutions, Inc. | Jacksonville | Florida | 32256 | — |
| Accel Research Sites Network - Lakeland CRU | Lakeland | Florida | 33803 | — |
| Accel Research Sites Network - Maitland CRU | Maitland | Florida | 32751 | — |
| Clinical Neuroscience Solutions, Inc. | Orlando | Florida | 32801 | — |
| CenExel iResearch, LLC | Savannah | Georgia | 31405 | — |
| Collective Medical Research | Overland Park | Kansas | 66210 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| Precise Research Centres | Flowood | Mississippi | 39232 | — |
| IMA Clinical Research | Las Vegas | Nevada | 89102 | — |
| SPRI Clinical Trials, LLC | Brooklyn | New York | 11235 | — |
| Neurobehavioral Research | Cedarhurst | New York | 11516 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10314 | — |
| Clinical Neuroscience Solutions, Inc. | Memphis | Tennessee | 38119 | — |
| Austin Clinical Trials Partners | Austin | Texas | 78737 | — |
| FutureSearch Trials of Dallas | Dallas | Texas | 75231 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Aim Trials | Plano | Texas | 75093 | — |
| Grayline Research Center | Wichita Falls | Texas | 76309 | — |
| Alpine Research Organization | Clinton | Utah | 84015 | — |
| Core Clinical Research | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05749055, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05749055 live on ClinicalTrials.gov.