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Completed Phase 3 Interventional Results available

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)

ClinicalTrials.gov ID: NCT05755438

Public ClinicalTrials.gov record NCT05755438. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 22, 2026, 4:42 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

Study identification

NCT ID
NCT05755438
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Incyte Corporation
Industry
Enrollment
204 participants

Conditions and interventions

Conditions

Interventions

  • Ruxolitinib Cream Drug
  • Vehicle Cream Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 9, 2023
Primary completion
Oct 6, 2024
Completion
Aug 12, 2025
Last update posted
Nov 13, 2025

2023 – 2025

United States locations

U.S. sites
18
U.S. states
14
U.S. cities
18
Facility City State ZIP Site status
Medical Dermatology Specialists Phoenix Phoenix Arizona 85006
Johnson Dermatology Fort Smith Arkansas 72916
First Oc Dermatology Fountain Valley California 92708
Dermatology Associates Pc Rockville Maryland 20850
Clarkston Medical Group Clarkston Michigan 48346
Revival Research Institute, Llc Troy Troy Michigan 48084
Medisearch Clinical Trials Saint Joseph Missouri 64506
Wake Forest University Winston-Salem North Carolina 27157
UC Health, Llc Cincinnati Ohio 45219
University Hospitals Cleveland Medical Center Cleveland Ohio 44106
Central Sooner Research Norman Oklahoma 73071
Dermatology Associates of Plymouth Meeting Plymouth Meeting Pennsylvania 19462
Medical University of South Carolina Charleston South Carolina 29425
International Clinical Research Tennessee Llc Murfreesboro Tennessee 37130
North Texas Center For Clinical Research Ntccr Frisco Texas 75034
Austin Institute For Clinical Research Aicr Pflugerville Pflugerville Texas 78660
Center For Clinical Studies Webster Texas 77598
Premier Clinical Research Spokane Washington 99204

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05755438, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Nov 13, 2025 · Synced Jul 22, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05755438 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →