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Completed Phase 3 Interventional Results available

A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Participants With Prurigo Nodularis (PN)

ClinicalTrials.gov ID: NCT05755438

Public ClinicalTrials.gov record NCT05755438. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:20 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the safety and tolerability of Ruxolitinib cream in participants with Prurigo Nodularis (PN).

Study identification

NCT ID
NCT05755438
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Incyte Corporation
Industry
Enrollment
204 participants

Conditions and interventions

Conditions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 10, 2023 (Actual)
Primary completion
Oct 7, 2024 (Actual)
Completion
Aug 13, 2025 (Actual)
Last update posted
Aug 12, 2026

2023 – 2025

United States locations

U.S. sites
18
U.S. states
14
U.S. cities
18
Facility City State ZIP Site status
Medical Dermatology Specialists Phoenix Phoenix Arizona 85006 —
Johnson Dermatology Fort Smith Arkansas 72916 —
First Oc Dermatology Fountain Valley California 92708 —
Dermatology Associates Pc Rockville Maryland 20850 —
Clarkston Medical Group Clarkston Michigan 48346 —
Revival Research Institute, Llc Troy Troy Michigan 48084 —
Medisearch Clinical Trials Saint Joseph Missouri 64506 —
Wake Forest University Winston-Salem North Carolina 27157 —
UC Health, Llc Cincinnati Ohio 45219 —
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 —
Central Sooner Research Norman Oklahoma 73071 —
Dermatology Associates of Plymouth Meeting Plymouth Meeting Pennsylvania 19462 —
Medical University of South Carolina Charleston South Carolina 29425 —
International Clinical Research Tennessee Llc Murfreesboro Tennessee 37130 —
North Texas Center For Clinical Research Ntccr Frisco Texas 75034 —
Austin Institute For Clinical Research Aicr Pflugerville Pflugerville Texas 78660 —
Center For Clinical Studies Webster Texas 77598 —
Premier Clinical Research Spokane Washington 99204 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 53 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05755438, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 12, 2026 · Synced Oct 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05755438 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →