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Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Birth to Three - Cavity Free

ClinicalTrials.gov ID: NCT05756413

Public ClinicalTrials.gov record NCT05756413. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 6:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Birth to Three - Cavity Free: Effectiveness of a Psychoeducational Intervention for ECC Prevention

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

Early childhood caries (ECC) is a potentially painful and debilitating disease, which represents a significant public health problem among young children. There are profound disparities in ECC experiences such that children from minority and low-income families suffer a disproportionate share of the disease burden. The likelihood of parents of high-ECC risk young children seeking prevention in dental facilities is low; therefore, there is a need to increase preventive dental opportunities where these children already seek health care services. In particular, there is an urgent need to develop and evaluate ECC behavioral interventions for use in public health settings attended by high-risk children. Many authors recommend early implementation of oral health education as one means of preventing ECC. However, major issues discussed in the oral health promotion literature involve a lack of effectiveness among programs based on education alone, as well as a lack of high quality preventive interventions using evidence-based psychological and behavioral strategies. Our research team has been the first to introduce to the ECC prevention arena the self-determination theory (SDT) of motivation, internalization, and healthy functioning, proven effective in promoting positive behavioral changes in several other fields, including oral health care. The investigators have demonstrated that SDT has great promise as a motivational approach by providing evidence, based on results from our R21 (R21-DE016483) study, of the effectiveness of SDT in changing several desirable oral health behaviors for ECC prevention. Building upon the rigor of our previous experience and formative research work in the past several years, the investigators propose a Stage II NIH Model research project that will compare the efficacy of autonomy-supportive videotaped oral health messages framed by SDT to more traditional neutral videotaped messages. The investigators intend to recruit 634 pregnant mothers enrolled in Iowa Women, Infants and Children (WIC) Supplemental Nutrition Programs and follow them until their future child is 36 months old. The primary outcome of interest will be children's caries status. Secondary outcomes will be changes in children's oral health behaviors conducive to better oral hygiene and dietary habits, as well as lower levels of dental plaque and mutans streptococci.

Study identification

NCT ID
NCT05756413
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Not applicable
Lead sponsor
University of Iowa
Other
Enrollment
1,268 participants

Conditions and interventions

Conditions

Interventions

Behavioral

Eligibility (public fields only)

Age range
18 Years to 45 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2023
Primary completion
Mar 30, 2027
Completion
Mar 30, 2027
Last update posted
Jul 20, 2026

2023 – 2027

United States locations

U.S. sites
16
U.S. states
1
U.S. cities
14
Facility City State ZIP Site status
Anamosa WIC Clinic Anamosa Iowa 52205
Belle Plaine WIC Clinic Belle Plaine Iowa 52208
LCPH WIC Clinic Cedar Rapids Iowa 52401
Urban WIC Clinic Cedar Rapids Iowa 52403
Clinton WIC Clinic Clinton Iowa 52732
Columbus Junction WIC Clinic Columbus Junction Iowa 52738
Davenport WIC Clinic Davenport Iowa 52801
CHC Edgerton Clinic Davenport Iowa 52803
Dewitt WIC Clinic De Witt Iowa 52742
Johnson County WIC Iowa City Iowa 52246
Maquoketa WIC Clinic Maquoketa Iowa 52060
Marion WIC Clinic Marion Iowa 52302
Monticello WIC Clinic Monticello Iowa 52310
Muscatine WIC Clinic Muscatine Iowa 52761
Tipton WIC Clinic Tipton Iowa 52772
Vinton WIC Clinic Vinton Iowa 52349

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05756413, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 20, 2026 · Synced Sep 6, 2026

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