A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma.
Public ClinicalTrials.gov record NCT05763121. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will assess the efficacy and safety of dexpramipexole as an adjunctive oral therapy in participants with inadequately controlled asthma with an eosinophilic phenotype and a history of asthma exacerbations.
Study identification
- NCT ID
- NCT05763121
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,061 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 29, 2023
- Primary completion
- Dec 7, 2025
- Completion
- Dec 7, 2025
- Last update posted
- Dec 14, 2025
2023 – 2025
United States locations
- U.S. sites
- 89
- U.S. states
- 26
- U.S. cities
- 76
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 20001-374 | Bakersfield | California | 93301 | — |
| Research Site 20001-440 | La Palma | California | 90623 | — |
| Research Site 20001-062 | Newport Beach | California | 92660 | — |
| Research Site 20001-043 | Newport Beach | California | 92663 | — |
| Research Site 20001-380 | Redding | California | 96001 | — |
| Research Site US-20001-488 | San Diego | California | 92108 | — |
| Research Site 20001-003 | West Covina | California | 91790 | — |
| Research Site 20001-419 | Westminster | California | 92683 | — |
| Research Site 20001-048 | Aventura | Florida | 33180 | — |
| Research Site 20001-005 | Brandon | Florida | 33511 | — |
| Research Site 20001-051 | Brandon | Florida | 33511 | — |
| Research Site 20001-029 | Coral Gables | Florida | 33134 | — |
| Research Site 20001-350 | Gainesville | Florida | 32607 | — |
| Research Site 20001-014 | Green Acres | Florida | 33467 | — |
| Research Site 20001-054 | Hialeah | Florida | 33012 | — |
| Research Site 20001-067 | Hialeah | Florida | 33016 | — |
| Research Site 20001-020 | Homestead | Florida | 33030 | — |
| Research Site 20001-015 | Kissimmee | Florida | 34744 | — |
| Research Site 20001-002 | Kissimmee | Florida | 34746 | — |
| Research Site 20001-086 | Loxahatchee Groves | Florida | 33470 | — |
| Research Site 20001-066 | Miami | Florida | 33126 | — |
| Research Site 20001-001 | Miami | Florida | 33135 | — |
| Research Site 20001-059 | Miami | Florida | 33144 | — |
| Research Site 20001-026 | Miami | Florida | 33155 | — |
| Research Site 20001-065 | Miami | Florida | 33173 | — |
| Research Site 20001-024 | Miami | Florida | 33184 | — |
| Research Site 20001-069 | St. Petersburg | Florida | 33713 | — |
| Research Site 20001-004 | Tampa | Florida | 33607 | — |
| Research Site 20001-075 | Augusta | Georgia | 30909 | — |
| Research Site 20001-018 | Columbus | Georgia | 31904 | — |
| Research Site 20001-459 | Sugar Hill | Georgia | 30518 | — |
| Research Site 20001-090 | Berwyn | Illinois | 60402 | — |
| Research Site 20001-476 | Chicago | Illinois | 60611 | — |
| Research Site 20001-358 | Normal | Illinois | 61761 | — |
| Research Site 20001-135 | River Forest | Illinois | 60305 | — |
| Research Site 20001-403 | Skokie | Illinois | 60077 | — |
| Research Site 20001-036 | Elwood | Indiana | 46036 | — |
| Research Site 20001-044 | Evansville | Indiana | 47715 | — |
| Research Site 20001-021 | Iowa City | Iowa | 52242 | — |
| Research Site 20001-019 | Owensboro | Kentucky | 42301 | — |
| Research Site 20001-466 | Baltimore | Maryland | 21237 | — |
| Research Site 20001-456 | Takoma Park | Maryland | 20912 | — |
| Research Site 20001-055 | White Marsh | Maryland | 21162 | — |
| Research Site 20001-468 | Fall River | Massachusetts | 02723 | — |
| Research Site 20001-006 | Flint | Michigan | 48504 | — |
| Research Site 20001-148 | Flint | Michigan | 48507 | — |
| Research Site 20001-463 | Rochester Hills | Michigan | 48307 | — |
| Research Site 20001-370 | Chesterfield | Missouri | 63005 | — |
| Research Site 20001-074 | Saint Charles | Missouri | 63301 | — |
| Research Site 20001-046 | St Louis | Missouri | 63110 | — |
| Research Site 20001-409 | Missoula | Montana | 59808 | — |
| Research Site 20001-486 | Henderson | Nevada | 89052 | — |
| Research Site 20001-473 | Las Vegas | Nevada | 89109 | — |
| Research Site 20001-471 | Highland Park | New Jersey | 08904 | — |
| Research Site 20001-457 | Jersey City | New Jersey | 07304 | — |
| Research Site 20001-420 | New Brunswick | New Jersey | 08901 | — |
| Research Site 20001-050 | East Amherst | New York | 14051 | — |
| Research Site 20001-047 | Hawthorne | New York | 10532 | — |
| Research Site 20001-422 | Rochester | New York | 14607 | — |
| Research Site 20001-368 | The Bronx | New York | 10455 | — |
| Research Site 20001-408 | Charlotte | North Carolina | 28273 | — |
| Research Site 20001-039 | Gastonia | North Carolina | 28054 | — |
| Research Site 20001-435 | Greenville | North Carolina | 27834 | — |
| Research Site 20001-382 | Raleigh | North Carolina | 27610 | — |
| Research Site 20001-034 | Cincinnati | Ohio | 45215 | — |
| Research Site 20001-013 | Cincinnati | Ohio | 45219 | — |
| Research Site 20001-017 | Dayton | Ohio | 45424 | — |
| Research Site 20001-063 | Toledo | Ohio | 43617 | — |
| Research Site 20001-038 | Edmond | Oklahoma | 73034 | — |
| Research Site 20001-079 | Oklahoma City | Oklahoma | 73120 | — |
| Research Site 20001-395 | Hershey | Pennsylvania | 17033 | — |
| Research Site 20001-032 | Columbia | South Carolina | 29204 | — |
| Research Site 20001-025 | Greenville | South Carolina | 29615 | — |
| Research Site 20001-073 | Spartanburg | South Carolina | 29303 | — |
| Research Site 20001-438 | Dickson | Tennessee | 37055 | — |
| Research Site 20001-068 | Amarillo | Texas | 79124 | — |
| Research Site 20001-023 | Dallas | Texas | 75230 | — |
| Research Site 20001-028 | Dallas | Texas | 75235 | — |
| Research Site 20001-064 | Houston | Texas | 77074 | — |
| Research Site 20001-085 | Houston | Texas | 77099 | — |
| Research Site 20001-478 | Plano | Texas | 75093 | — |
| Research Site 20001-072 | The Woodlands | Texas | 77380 | — |
| Research Site 20001-258 | Murray | Utah | 84107 | — |
| Research Site 20001-477 | Salt Lake City | Utah | 84107 | — |
| Research Site 20001-340 | Burke | Virginia | 22015 | — |
| Research Site 20001-479 | Vienna | Virginia | 22180 | — |
| Research Site 20001-480 | Barboursville | West Virginia | 25504 | — |
| Research Site 20001-433 | La Crosse | Wisconsin | 54601 | — |
| Research Site 20001-057 | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 312 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05763121, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 14, 2025 · Synced Sep 2, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05763121 live on ClinicalTrials.gov.