Efficacy and Safety of SYNB1934 in Patients With PKU (SYNPHENY-3)
Public ClinicalTrials.gov record NCT05764239. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-blind, Placebo-controlled, Randomized Withdrawal Study to Evaluate the Efficacy and Safety of SYNB1934 in Patients With PKU (SYNPHENY-3)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
SYNB1934-CP-003 was designed as a 3-part, adaptive study consisting of a dose-escalating, open-label period (DEP; Part 1) of up to 15 weeks, followed by a 4-week, double-blind, placebo-controlled, randomized withdrawal period (RWP; Part 2), and an open-label extension (OLE; Part 3) of up to 36 months
Study identification
- NCT ID
- NCT05764239
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 35 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 5, 2023 (Actual)
- Primary completion
- Mar 15, 2024 (Actual)
- Completion
- Mar 15, 2024 (Actual)
- Last update posted
- Jun 20, 2024
2023 – 2024
United States locations
- U.S. sites
- 14
- U.S. states
- 10
- U.S. cities
- 14
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Science 37 | Culver City | California | 90230 | — |
| Children's Hospital Orange County | Orange | California | 92868 | — |
| Stanford University, Department of Pediatrics | Palo Alto | California | 94304 | — |
| University of Colorado Children's Hospital | Aurora | Colorado | 80045 | — |
| University of Florida - Gainesville | Gainesville | Florida | 32610 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago, Pediatrics | Chicago | Illinois | 60611-2991 | — |
| Massachusetts General Hospital, Department of Pediatrics | Boston | Massachusetts | 02114 | — |
| Oregon Health and Science University Department of Molecular and Medical Genetics | Portland | Oregon | 97239 | — |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center - Children's Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | — |
| Medical University of South Carolina, Pediatrics | Charleston | South Carolina | 29425 | — |
| Division of Medical Genetics-Pediatrics, Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| McGovern Medical School/Memorial Hermann Hospital | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 7 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05764239, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 20, 2024 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05764239 live on ClinicalTrials.gov.