Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)
Public ClinicalTrials.gov record NCT05767034. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Parallel-group, Double-blind, Placebo-controlled, Multicenter Phase III Trial to Evaluate Efficacy and Safety of Secukinumab Administered Subcutaneously Versus Placebo, in Combination With a Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to demonstrate the efficacy and safety of secukinumab 300 milligram (mg) and 150 mg administered subcutaneously (s.c.) for 52 weeks in combination with prednisone tapered over 24 weeks in adult participants with PMR who have recently relapsed.
Study identification
- NCT ID
- NCT05767034
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 381 participants
Conditions and interventions
Conditions
Interventions
- Secukinumab 300 mg Drug
- Secukinumab 150 mg Drug
- Placebo to secukinumab Other
Drug · Other
Eligibility (public fields only)
- Age range
- 50 Years to 100 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 22, 2023 (Actual)
- Primary completion
- Sep 10, 2025 (Actual)
- Completion
- Feb 16, 2026 (Actual)
- Last update posted
- Jun 22, 2026
2023 – 2026
United States locations
- U.S. sites
- 22
- U.S. states
- 11
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arthritis and Rheumatology Associates PLLC | Avondale | Arizona | 85392 | — |
| Sun Valley Arthritis Center Ltd | Peoria | Arizona | 85381 | — |
| AZ Arthritis and Rheumtlgy Rsh PLLC | Phoenix | Arizona | 85032 | — |
| Precn Comprehensive Clnl Rsch Solns | San Leandro | California | 94578 | — |
| Providence Saint Johns Health Ctr | Santa Monica | California | 90404 | — |
| Center for Rheumatology Research | West Hills | California | 91307 | — |
| Millennium Clinical Trials | Westlake Village | California | 91361 | — |
| Rheumatology Associates of South Florida | Boca Raton | Florida | 33486 | — |
| UF Health Cancer Center | Gainesville | Florida | 32610 | — |
| Sarasota Arthritis Res Ctr | Sarasota | Florida | 34239 | — |
| West Broward Rheumatology Associates Inc | Tamarac | Florida | 33321 | — |
| Southeastern Rheumatology Alliance | Gainesville | Georgia | 30501 | — |
| Klein and Associates | Hagerstown | Maryland | 21740 | — |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | — |
| Clinical Research Inst of MI | Saint Clair Shores | Michigan | 48081 | — |
| Kansas City Physician Partners | Kansas City | Missouri | 64111 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Paramount Med Rsrch and Consult LLC | Middleburg Heights | Ohio | 44130 | — |
| Prolato Clinical Research Center | Houston | Texas | 77054 | — |
| DM Clinical Research | Houston | Texas | 77070 | — |
| Accurate Clinical Research Inc | Houston | Texas | 77089 | — |
| Advanced Rheumatology of Houston | Spring | Texas | 77382 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 110 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05767034, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 22, 2026 · Synced Oct 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05767034 live on ClinicalTrials.gov.