A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401)
Public ClinicalTrials.gov record NCT05768386. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Long-Term Follow-Up Study in Subjects With Severe Hemophilia A Who Received BMN 270, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Factor VIII in a Prior BioMarin Clinical Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The BMN 270 clinical development program consists of multiple interventional studies designed to assess the safety and efficacy of a single infusion of BMN 270 for at least 5 years post-infusion. This long-term follow-up study is needed to help further understand the long-term safety of BMN 270 beyond 5 years and to assess the durability of efficacy.
Study identification
- NCT ID
- NCT05768386
- Recruitment status
- Enrolling by invitation
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 172 participants
Conditions and interventions
Conditions
Interventions
Not listed
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 1, 2023 (Actual)
- Primary completion
- Jan 2040 (Estimated)
- Completion
- Jan 2040 (Estimated)
- Last update posted
- Jan 12, 2026
2023 – 2040
United States locations
- U.S. sites
- 13
- U.S. states
- 8
- U.S. cities
- 13
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Orthopedic Institute for Children, Orthopedic Hemophilia Treatment Center | Los Angeles | California | 90007 | — |
| UC Davis Hemophilia Treatment Center | Sacramento | California | 95817 | — |
| University of California San Diego, Hemophilia & Thrombosis Treatment Center | San Diego | California | 92121 | — |
| University of California San Francisco - Moffit Hospital, Outpatient Hematology Clinic | San Francisco | California | 94143 | — |
| UCN Hemophilia and Thrombosis Center | Shandon | California | 27517 | — |
| Hemophilia and Thrombosis Center at the University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| St Joseph's Children's Hospital, Center for Bleeding and Clotting Disorders | Tampa | Florida | 33614 | — |
| University Medical Center, Inc,; DBA University of Louisville Hospital, James Graham Brown Cancer Center | Louisville | Kentucky | 40202-3229 | — |
| University of Michigan, Pediatric Hematology and Oncology | Ann Arbor | Michigan | 48109-5718 | — |
| Children's Hospital of Michigan, Hemophilia and Thrombosis Center | Detroit | Michigan | 48201 | — |
| Washington University School of Medicine, Department of Pediatrics, Division of Hematology/Oncology | St Louis | Missouri | 63110-1093 | — |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | — |
| Hemophilia Center of Western Pennsylvania | Pittsburgh | Pennsylvania | 15213 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05768386, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 12, 2026 · Synced Oct 26, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05768386 live on ClinicalTrials.gov.