LY3819253 (LY-CoV555) for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Public ClinicalTrials.gov record NCT05780268. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19 (Trial H1: LY3819253 (LY-CoV555))
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study looks at the safety and effectiveness of LY3819253 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either LY3819253 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H1.
Study identification
- NCT ID
- NCT05780268
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 314 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 5, 2020 (Actual)
- Primary completion
- Feb 1, 2021 (Actual)
- Completion
- Feb 1, 2021 (Actual)
- Last update posted
- Dec 27, 2023
2020 – 2021
United States locations
- U.S. sites
- 42
- U.S. states
- 24
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center Tucson (Site 206-004), 1625 N. Campbell Avenue | Tucson | Arizona | 85719 | — |
| Community Regional Medical Center (Site 203-005), 2823 Fresno Street | Fresno | California | 93701 | — |
| Keck Hospital of USC (Site 301-020), 1500 San Pablo Street | Los Angeles | California | 90033 | — |
| UCSF Medical Center at Mount Zion (Site 203-007), 1600 Divisadero St. | San Francisco | California | 94115 | — |
| San Francisco VAMC (Site 074-002), 4150 Clement St. | San Francisco | California | 94121 | — |
| UCSF Medical Center (Site 203-001), Moffitt-Long Hospital, 505 Parnassus Ave. | San Francisco | California | 94143 | — |
| Stanford University Hospital & Clinics (Site 203-003), 300 Pasteur Dr. | Stanford | California | 94305 | — |
| University of Colorado Hospital (Site 204-001), 12605 E. 16th Avenue | Aurora | Colorado | 80045 | — |
| Denver Public Health (Site 017-004), 660 Bannock St., MC2600 (Infectious Disease Clinic) | Denver | Colorado | 80204 | — |
| MedStar Georgetown University Hospital (Site 067-001), 3800 Reservoir Road NW | Washington D.C. | District of Columbia | 20007 | — |
| Miami VAMC (Site 074-003), 1201 NW 16 Street | Miami | Florida | 33125 | — |
| Emory University (Site 301-008), The Emory Clinic, Bldg. A, Suite 2236, 1365 Clifton Rd., NE | Atlanta | Georgia | 30322 | — |
| University of Kentucky Hospital (Site 210-004), 1000 South Limestone St. | Lexington | Kentucky | 40536 | — |
| Ochsner Clinic Foundation (Site 301-015), 1514 Jefferson Highway | New Orleans | Louisiana | 70121 | — |
| University of Maryland Medical Center (Site 301-019), 22 South Greene Street | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital (Site 202-002), 55 Fruit Street | Boston | Massachusetts | 02114 | — |
| Baystate Medical Center (Site 201-001), 759 Chestnut Street | Springfield | Massachusetts | 01199 | — |
| University of Michigan (Site 205-001), 1500 East Medical Center Drive | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System, Henry Ford Hospital (Site 014-001), 2799 W. Grand Blvd. | Detroit | Michigan | 48202 | — |
| Hennepin Healthcare (Site 027-001), 701 Park Avenue | Minneapolis | Minnesota | 55415 | — |
| University of Mississippi Medical Center (Site 202-005), 2500 North State Street | Jackson | Mississippi | 39216 | — |
| Dartmouth-Hitchcock Medical Center/Mary Hitchcock Memorial Hospital (Site 301-024), One Medical Center Drive | Lebanon | New Hampshire | 03756 | — |
| Montefiore Medical Center Weiler Hospital (Site 206-003), 1825 Eastchester Road | The Bronx | New York | 10461 | — |
| Montefiore Medical Center Moses Hospital (Site 206-001), 111 E. 210th Street | The Bronx | New York | 10467 | — |
| Duke University Hospital (Site 301-006), 2301 Erwin Road | Durham | North Carolina | 27710 | — |
| Wake Forest University Health Sciences (Site 210-001), Medical Center Blvd | Winston-Salem | North Carolina | 27157 | — |
| Cleveland Clinic Fairview Hospital (Site 207-005), 18101 Lorain Avenue | Cleveland | Ohio | 44111 | — |
| Cleveland Clinic Foundation (Site 207-001), 9500 Euclid Avenue | Cleveland | Ohio | 44195 | — |
| Cleveland Clinic Marymount Hospital (Site 207-006), 12300 McCraken Road | Garfield Heights | Ohio | 44125 | — |
| Oregon Health & Science University (Site 208-003), 3181 SW Sam Jackson Park Rd. | Portland | Oregon | 97239-3098 | — |
| Vanderbilt University Medical Center (Site 212-001), 1211 Medical Center Drive | Nashville | Tennessee | 37232 | — |
| UT Southwestern Medical Center (Site 084-001), 1936 Amelia Court, 2nd Floor | Dallas | Texas | 75235 | — |
| Baylor, Scott and White Health (Site 301-003), Baylor University Medical Center, 3500 Gaston Ave. | Dallas | Texas | 75246 | — |
| Memorial Hermann Hospital (Site 203-006), 6411 Fannin Street | Houston | Texas | 77030 | — |
| Michael E. DeBakey Veterans Affairs Medical Center (MEDV AMC) (Site 074-006), 2002 Holcombe Blvd. | Houston | Texas | 77030 | — |
| Intermountain Medical Center (Site 211-001), 5121 South Cottonwood Street | Murray | Utah | 84107 | — |
| University of Utah Hospital (Site 211-002), 419 Wakara Way, Suite 207 | Salt Lake City | Utah | 84108 | — |
| University of Virginia Health Systems (Site 301-021), 1215 Lee Street | Charlottesville | Virginia | 22903 | — |
| Virginia Commonwealth University Health System (Site 210-005), 1250 East Marshall Street | Richmond | Virginia | 23298 | — |
| Harborview Medical Center (Site 208-001), 325 9th Avenue | Seattle | Washington | 98104 | — |
| University of Washington Medical Center - Montlake (Site 208-006), 1959 NE Pacific Street | Seattle | Washington | 98195 | — |
| West Virginia University (Site 301-023), One Medical Center Drive | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05780268, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 27, 2023 · Synced Oct 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05780268 live on ClinicalTrials.gov.