ClinicalTrials.gov record
MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
ClinicalTrials.gov ID: NCT05780463
Public ClinicalTrials.gov record NCT05780463. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19 (Trial H5: MP0420)
Study identification
- NCT ID
- NCT05780463
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
- NIH
- Enrollment
- 485 participants
Conditions and interventions
Conditions
Interventions
- MP0420 Drug
- Placebo Drug
- Remdesivir Biological
Drug · Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 10, 2021
- Primary completion
- Feb 22, 2022
- Completion
- Jun 7, 2023
- Last update posted
- Feb 4, 2024
2021 – 2023
United States locations
- U.S. sites
- 73
- U.S. states
- 29
- U.S. cities
- 55
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Banner University Medical Center Tucson (Site 206-004), 1625 N. Campbell Avenue | Tucson | Arizona | 85719 | — |
| Southern Arizona VA Healthcare System (Site 074-009), 3601 S. 6th Ave. | Tucson | Arizona | 85723 | — |
| Velocity Chula Vista (Site 080-034), 752 Medical Center Ct., Ste. 304 | Chula Vista | California | 91911 | — |
| Community Regional Medical Center (Site 203-005), 2823 Fresno Street | Fresno | California | 93701 | — |
| Velocity San Diego (Site 080-035), 5565 Grossmont Center Drive, Building 2, Suite 1 | La Mesa | California | 91942 | — |
| VA Long Beach Healthcare System (Site 074-026), 5901 East 7th Street (09/151-M2) | Long Beach | California | 90822 | — |
| Cedars-Sinai Medical Center (Site 208-002), 8700 Beverly Blvd. | Los Angeles | California | 90048 | — |
| Ronald Reagan UCLA Medical Center (Site 203-002), 757 Westwood Plaza | Los Angeles | California | 90095 | — |
| Sacramento VA Medical Center (Site 074-023), 10535 Hospital Way | Mather | California | 95655 | — |
| Hoag Memorial Hospital Presbyterian (Site 080-026), One Hoag Drive | Newport Beach | California | 92663 | — |
| UC Davis Health (Site 203-004), 2315 Stockton Blvd. | Sacramento | California | 95817 | — |
| VA San Diego Healthcare System (Site 074-016), 3350 La Jolla Village Drive | San Diego | California | 92161 | — |
| UCSF Medical Center at Mount Zion (Site 203-007), 1600 Divisadero St. | San Francisco | California | 94115 | — |
| San Francisco VAMC (Site 074-002), 4150 Clement St. | San Francisco | California | 94121 | — |
| UCSF Medical Center (Site 203-001), Moffitt-Long Hospital, 505 Parnassus Ave. | San Francisco | California | 94143 | — |
| Stanford University Hospital & Clinics (Site 203-003), 300 Pasteur Dr. | Stanford | California | 94305 | — |
| Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (Site 066-002), 1124 W. Carson Street, CDCRC Building | Torrance | California | 90502 | — |
| University of Colorado Hospital (Site 204-001), 12605 E. 16th Avenue | Aurora | Colorado | 80045 | — |
| Denver Public Health (Site 017-004), 660 Bannock St., MC2600 (Infectious Disease Clinic) | Denver | Colorado | 80204 | — |
| West Haven VA Medical Center (Site 025-007), 950 Campbell Avenue | West Haven | Connecticut | 06516 | — |
| MedStar Health Research Institute (Site 009-021), MedStar Washington Hospital Center, 110 Irving St., NW. | Washington D.C. | District of Columbia | 20010 | — |
| Washington DC VA Medical Center (Site 009-004), 50 Irving Street NW | Washington D.C. | District of Columbia | 20422 | — |
| Bay Pines VAMC (Site 074-004), 10000 Bay Pines Blvd., Bldg. 100, Room 5B-104 | Bay Pines | Florida | 33744 | — |
| Miami VAMC (Site 074-003), 1201 NW 16 Street | Miami | Florida | 33125 | — |
| Hillsborough County Health Department, University of South Florida (Site 032-001) | Tampa | Florida | 33602 | — |
| Emory University (Site 301-008), The Emory Clinic, Bldg. A, Suite 2236, 1365 Clifton Rd., NE | Atlanta | Georgia | 30322 | — |
| Lutheran Medical Group (Site 301-010), 7916 W. Jefferson Boulevard | Fort Wayne | Indiana | 46804 | — |
| Cotton O'Neil Clinical Research Center (Site 080-030), Stormont Vail Health, 1500 SW 10th Avenue | Topeka | Kansas | 66604 | — |
| Ochsner Clinic Foundation (Site 301-015), 1514 Jefferson Highway | New Orleans | Louisiana | 70121 | — |
| University of Maryland Medical Center (Site 301-019), 22 South Greene Street | Baltimore | Maryland | 21201 | — |
| Massachusetts General Hospital (Site 202-002), 55 Fruit Street | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center (Site 202-001), 330 Brookline Ave. | Boston | Massachusetts | 02215 | — |
| Baystate Medical Center (Site 201-001), 759 Chestnut Street | Springfield | Massachusetts | 01199 | — |
| University of Michigan (Site 205-001), 1500 East Medical Center Drive | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System, Henry Ford Hospital (Site 014-001), 2799 W. Grand Blvd. | Detroit | Michigan | 48202 | — |
| Minneapolis Heart Institute Foundation (Site 301-026), Abbott Northwestern Hospital, 920 E 28th St. #100 | Minneapolis | Minnesota | 55407 | — |
| Hennepin Healthcare (Site 027-001), 701 Park Avenue | Minneapolis | Minnesota | 55415 | — |
| Minneapolis VA Health Care System (Site 105-001), 1 Veterans Drive, Bldg 70 | Minneapolis | Minnesota | 55417 | — |
| M Health Fairview University of Minnesota Medical Center (Site 112-001), 500 Harvard St. SE. | Minneapolis | Minnesota | 55455 | — |
| University of Mississippi Medical Center (Site 202-005), 2500 North State Street | Jackson | Mississippi | 39216 | — |
| Dartmouth-Hitchcock Medical Center/Mary Hitchcock Memorial Hospital (Site 301-024), One Medical Center Drive | Lebanon | New Hampshire | 03756 | — |
| Cooper University Hospital (Site 019-001), One Cooper Plaza | Camden | New Jersey | 08103 | — |
| SUNY Downstate Medical Center (Site 033-001), 450 Clarkson Ave. | Brooklyn | New York | 11203 | — |
| Maimonides Medical Center (Site 033-002), 4802 10th Avenue | Brooklyn | New York | 11219 | — |
| Lincoln Medical Center (New York Health and Hospitals/Lincoln) (Site 003-016), 234 E. 149th Street | The Bronx | New York | 10451 | — |
| Montefiore Medical Center Moses Hospital (Site 206-001), 111 E. 210th Street | The Bronx | New York | 10467 | — |
| Duke University Hospital (Site 301-006), 2301 Erwin Road | Durham | North Carolina | 27710 | — |
| Wake Forest University Health Sciences (Site 210-001), Medical Center Blvd | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati Medical Center (Site 207-003), 234 Goodman Ave. | Cincinnati | Ohio | 45219 | — |
| University Hospitals Cleveland Medical Center (Site 108-001), 11100 Euclid Avenue | Cleveland | Ohio | 44106 | — |
| Oregon Health & Science University (Site 208-003), 3181 SW Sam Jackson Park Rd. | Portland | Oregon | 97239-3098 | — |
| Portland VA Healthcare System (Site 074-024), 3710 SW. US Veterans Hospital Road | Portland | Oregon | 97239 | — |
| Rhode Island Hospital (Site 080-036), 593 Eddy Street | Providence | Rhode Island | 02903 | — |
| The Miriam Hospital (Site 080-039), 164 Summit Ave. | Providence | Rhode Island | 02906 | — |
| Ralph H. Johnson VA Medical Center (Site 074-015), 109 Bee Street | Charleston | South Carolina | 29401 | — |
| MUSC Research Nexus Clinic (Site 210-002), 96 Jonathan Lucas St., CSB 214 | Charleston | South Carolina | 29425 | — |
| MUSC Health Florence Medical Center (Site 210-006), 805 Pamplico Highway | Florence | South Carolina | 29505 | — |
| VA TVHS Nashville Campus (Site 074-022), 1310 24th Avenue South | Nashville | Tennessee | 37212 | — |
| Vanderbilt University Medical Center (Site 212-001), 1211 Medical Center Drive | Nashville | Tennessee | 37232 | — |
| Hendrick Medical Center (Site 080-014), 1900 Pine Street | Abilene | Texas | 79601 | — |
| CHRISTUS Spohn Shoreline Hospital (Site 080-001), 600 Elizabeth Street | Corpus Christi | Texas | 78404 | — |
| Parkland Health and Hospital Systems (Site 084-002), 5200 Harry Hines Blvd | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center (Site 084-001), 1936 Amelia Court, 2nd Floor | Dallas | Texas | 75235 | — |
| Baylor, Scott and White Health (Site 301-003), Baylor University Medical Center, 3500 Gaston Ave. | Dallas | Texas | 75246 | — |
| Michael E. DeBakey Veterans Affairs Medical Center (MEDV AMC) (Site 074-006), 2002 Holcombe Blvd. | Houston | Texas | 77030 | — |
| Texas Heart Institute (Site 301-017), 6770 Bertner, MC4-266 | Houston | Texas | 77030 | — |
| CHRISTUS Good Shepherd Medical Center (Site 080-031), 700 E. Marshall Ave. | Longview | Texas | 75601 | — |
| Intermountain Medical Center (Site 211-001), 5121 South Cottonwood Street | Murray | Utah | 84107 | — |
| University of Virginia Health Systems (Site 301-021), 1215 Lee Street | Charlottesville | Virginia | 22903 | — |
| Carilion Roanoke Memorial Hospital (Site 080-018), 1906 Belleview Avenue | Roanoke | Virginia | 24014 | — |
| Salem VA Medical Center (Site 074-014), 1970 Roanoke Blvd. | Salem | Virginia | 24153 | — |
| Swedish Hospital First Hill (Site 208-005), 747 Broadway | Seattle | Washington | 98122 | — |
| West Virginia University (Site 301-023), One Medical Center Drive | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 32 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05780463, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 4, 2024 · Synced May 7, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05780463 live on ClinicalTrials.gov.