PF-07304814 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial)
Public ClinicalTrials.gov record NCT05780541. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Adaptive, Randomized, Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for Hospitalized Patients With COVID-19 (Trial H6: PF-07304814)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study looks at the safety and effectiveness of PF-07304814 in treating COVID-19 in people who have been hospitalized with the infection. Participants in the study will be treated with either PF-07304814 plus current standard of care (SOC), or with placebo plus current SOC. This is ACTIV-3/TICO Treatment Trial H6.
Study identification
- NCT ID
- NCT05780541
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 58 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 15, 2021 (Actual)
- Primary completion
- Apr 6, 2022 (Actual)
- Completion
- Jul 14, 2023 (Actual)
- Last update posted
- Feb 9, 2024
2021 – 2023
United States locations
- U.S. sites
- 31
- U.S. states
- 17
- U.S. cities
- 26
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Velocity Chula Vista (Site 080-034), 752 Medical Center Ct., Ste. 304 | Chula Vista | California | 91911 | — |
| Cedars-Sinai Medical Center (Site 208-002), 8700 Beverly Blvd. | Los Angeles | California | 90048 | — |
| Sacramento VA Medical Center (Site 074-023), 10535 Hospital Way | Mather | California | 95655 | — |
| Hoag Memorial Hospital Presbyterian (Site 080-026), One Hoag Drive | Newport Beach | California | 92663 | — |
| Palo Alto VAMC (Site 074-005), 3801 Miranda Avenue | Palo Alto | California | 94304 | — |
| UC Davis Health (Site 203-004), 2315 Stockton Blvd. | Sacramento | California | 95817 | — |
| VA San Diego Healthcare System (Site 074-016), 3350 La Jolla Village Drive | San Diego | California | 92161 | — |
| San Francisco VAMC (Site 074-002), 4150 Clement St. | San Francisco | California | 94121 | — |
| National Jewish Health / St. Joseph Hospital (Site 204-003), 1400 Jackson Street | Denver | Colorado | 80206 | — |
| West Haven VA Medical Center (Site 025-007), 950 Campbell Avenue | West Haven | Connecticut | 06516 | — |
| MedStar Health Research Institute (Site 009-021), MedStar Washington Hospital Center, 110 Irving St., NW. | Washington D.C. | District of Columbia | 20010 | — |
| Bay Pines VAMC (Site 074-004), 10000 Bay Pines Blvd., Bldg. 100, Room 5B-104 | Bay Pines | Florida | 33744 | — |
| Hillsborough County Health Department, University of South Florida (Site 032-001) | Tampa | Florida | 33602 | — |
| Lutheran Medical Group (Site 301-010), 7916 W. Jefferson Boulevard | Fort Wayne | Indiana | 46804 | — |
| Ochsner Clinic Foundation (Site 301-015), 1514 Jefferson Highway | New Orleans | Louisiana | 70121 | — |
| Massachusetts General Hospital (Site 202-002), 55 Fruit Street | Boston | Massachusetts | 02114 | — |
| Beth Israel Deaconess Medical Center (Site 202-001), 330 Brookline Ave. | Boston | Massachusetts | 02215 | — |
| Henry Ford Health System, Henry Ford Hospital (Site 014-001), 2799 W. Grand Blvd. | Detroit | Michigan | 48202 | — |
| Dartmouth-Hitchcock Medical Center/Mary Hitchcock Memorial Hospital (Site 301-024), One Medical Center Drive | Lebanon | New Hampshire | 03756 | — |
| Duke University Hospital (Site 301-006), 2301 Erwin Road | Durham | North Carolina | 27710 | — |
| Portland VA Healthcare System (Site 074-024), 3710 SW. US Veterans Hospital Road | Portland | Oregon | 97239 | — |
| Rhode Island Hospital (Site 080-036), 593 Eddy Street | Providence | Rhode Island | 02903 | — |
| The Miriam Hospital (Site 080-039), 164 Summit Ave. | Providence | Rhode Island | 02906 | — |
| Ralph H. Johnson VA Medical Center (Site 074-015), 109 Bee Street | Charleston | South Carolina | 29401 | — |
| MUSC Research Nexus Clinic (Site 210-002), 96 Jonathan Lucas St., CSB 214 | Charleston | South Carolina | 29425 | — |
| MUSC Health Florence Medical Center (Site 210-006), 805 Pamplico Highway | Florence | South Carolina | 29505 | — |
| Parkland Health and Hospital Systems (Site 084-002), 5200 Harry Hines Blvd | Dallas | Texas | 75235 | — |
| UT Southwestern Medical Center (Site 084-001), 1936 Amelia Court, 2nd Floor | Dallas | Texas | 75235 | — |
| Baylor, Scott and White Health (Site 301-003), Baylor University Medical Center, 3500 Gaston Ave. | Dallas | Texas | 75246 | — |
| University of Utah Hospital (Site 211-002), 419 Wakara Way, Suite 207 | Salt Lake City | Utah | 84108 | — |
| West Virginia University (Site 301-023), One Medical Center Drive | Morgantown | West Virginia | 26506 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05780541, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 9, 2024 · Synced Oct 17, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05780541 live on ClinicalTrials.gov.