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Terminated Phase 1 Interventional Results available

A Safety, Tolerability and Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

ClinicalTrials.gov ID: NCT05787496

Public ClinicalTrials.gov record NCT05787496. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 8, 2026, 4:25 PM EST

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Official title

A Phase 1, Open-Label, Safety, Tolerability, And Efficacy Study of NC525 in Subjects With Advanced Myeloid Neoplasms

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is an open-label, non-randomized, Phase 1 study to determine the safety and tolerability of NC525. This study will also assess the clinical benefit in subjects with advanced myeloid neoplasms.

Study identification

NCT ID
NCT05787496
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
NextCure, Inc.
Industry
Enrollment
28 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 28, 2023 (Actual)
Primary completion
Jan 31, 2025 (Actual)
Completion
Jan 31, 2025 (Actual)
Last update posted
Jan 28, 2026

2023 – 2025

United States locations

U.S. sites
11
U.S. states
8
U.S. cities
9
Facility City State ZIP Site status
City of Hope Duarte California 91010 —
University of Miami Miami Florida 33136 —
Massachusetts General Hospital Boston Massachusetts 02114 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Washington University School of Medicine in St. Louis St Louis Missouri 63110 —
Roswell Park Cancer Institute Buffalo New York 14263 —
Weill Cornell Medicine New York New York 10022 —
University Hospitals Cleveland Medical Center Cleveland Ohio 44106 —
Cleveland Clinic Cleveland Ohio 44195 —
Oregon Health & Science University Portland Oregon 97239 —
MD Anderson Cancer Center Houston Texas 77030 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05787496, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 28, 2026 · Synced Nov 8, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05787496 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →