Phase 2B Micronized DHACM vs. Saline in the Treatment of Knee Osteoarthritis
Public ClinicalTrials.gov record NCT05796765. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2B, Prospective, Double-Blind, Randomized Controlled Trial of the Micronized DHACM Injectable Product Compared to Saline Placebo Injection for the Treatment of Osteoarthritis of the Knee
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine the safety and efficacy of the 40 mg and 100 mg doses of allogeneic micronized dehydrated human amnion/chorion membrane (micronized DHACM) injectable compared to 0.9% sodium chloride injection, placebo control for the treatment of knee osteoarthritis
Study identification
- NCT ID
- NCT05796765
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 43 participants
Conditions and interventions
Conditions
Interventions
- Micronized DHACM 40 mg Biological
- Micronized DHACM 100 mg Biological
- Saline Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 21 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 24, 2023 (Actual)
- Primary completion
- Dec 15, 2023 (Actual)
- Completion
- Dec 15, 2023 (Actual)
- Last update posted
- Jan 17, 2024
2023
United States locations
- U.S. sites
- 14
- U.S. states
- 9
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Horizon Clinical Research | La Mesa | California | 91942 | — |
| AppleMed Research Group, LLC | Miami | Florida | 33126 | — |
| Health and Life Research Institute, LLC | Miami | Florida | 33155 | — |
| Vista Health Research, LLC | Miami | Florida | 33176 | — |
| Premier Medical Associates | The Villages | Florida | 32159 | — |
| Elite Clinical Trials, LLLP | Blackfoot | Idaho | 83221 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| University Orthopedics Center - Altoona | Altoona | Pennsylvania | 16602 | — |
| University Orthopedics Center - State College | State College | Pennsylvania | 16801 | — |
| Clinical Trials of South Carolina | Charleston | South Carolina | 29406 | — |
| Piedmont Research Partners, LLC | Fort Mill | South Carolina | 29707 | — |
| ClinRX Research Joseph, Inc. | Carrollton | Texas | 75007 | — |
| J. Lewis Research Inc. / Foothill Family Clinic Draper | Draper | Utah | 84020 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05796765, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 17, 2024 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05796765 live on ClinicalTrials.gov.