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Completed Phase 2 Interventional Results available

A Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

ClinicalTrials.gov ID: NCT05809934

Public ClinicalTrials.gov record NCT05809934. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 29, 2026, 4:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomised, Double-blind, Placebo-controlled, Multi-centre Phase 2b Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 in Participants With Non-cirrhotic Non-alcoholic Steatohepatitis (NASH) With Fibrosis Who Are Carriers of the PNPLA3 rs738409 148M Risk Allele

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhotic non-alcoholic steatohepatitis with fibrosis and who are carriers of the PNPLA3 148M Risk Allele

Study identification

NCT ID
NCT05809934
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
220 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Mar 15, 2023 (Actual)
Primary completion
Jul 14, 2025 (Actual)
Completion
Sep 29, 2025 (Actual)
Last update posted
Oct 28, 2026

2023 – 2025

United States locations

U.S. sites
36
U.S. states
15
U.S. cities
35
Facility City State ZIP Site status
Research Site Chandler Arizona 85224 —
Research Site Peoria Arizona 85381 —
Research Site Surprise Arizona 85378 —
Research Site Tucson Arizona 85712 —
Research Site Tucson Arizona 85715 —
Research Site Gardena California 90247 —
Research Site La Mesa California 91942 —
Research Site Lancaster California 93534 —
Research Site Los Angeles California 90017 —
Research Site Montclair California 91763 —
Research Site Orange California 92868 —
Research Site Rialto California 92377 —
Research Site Santa Ana California 92704 —
Research Site Boca Raton Florida 33434 —
Research Site Hialeah Florida 33016 —
Research Site Jacksonville Florida 32216 —
Research Site Port Orange Florida 32127 —
Research Site Winter Park Florida 32792 —
Research Site Marietta Georgia 30060 —
Research Site Topeka Kansas 66606 —
Research Site Detroit Michigan 48202 —
Research Site Las Vegas Nevada 89101 —
Research Site Westlake Ohio 44145 —
Research Site Chickasha Oklahoma 73018 —
Research Site Hershey Pennsylvania 17033 —
Research Site Summerville South Carolina 29485 —
Research Site Cordova Tennessee 38018 —
Research Site Austin Texas 78757 —
Research Site Brownsville Texas 78520 —
Research Site Denison Texas 75020 —
Research Site DeSoto Texas 75115 —
Research Site Edinburg Texas 78539 —
Research Site San Antonio Texas 78229 —
Research Site Sugar Land Texas 77478 —
Research Site Richmond Virginia 23249 —
Research Site Seattle Washington 98105 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 127 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05809934, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 28, 2026 · Synced Oct 29, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05809934 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →