Parallel Arm Trial of AD109 and Placebo With Patients With OSA (LunAIRo)
Public ClinicalTrials.gov record NCT05811247. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3 Randomized Double-Blind Placebo-Controlled 1-year Parallel-Arm Study to Compare a Fixed Dose Combination of Aroxybutynin/Atomoxetine (AD109) to Placebo in Obstructive Sleep Apnea (LunAIRo Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3 Randomized Double-Blind Placebo-Controlled 1-year Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.
Study identification
- NCT ID
- NCT05811247
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 660 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 28, 2023 (Actual)
- Primary completion
- May 7, 2025 (Actual)
- Completion
- May 7, 2025 (Actual)
- Last update posted
- Nov 21, 2025
2023 – 2025
United States locations
- U.S. sites
- 64
- U.S. states
- 26
- U.S. cities
- 62
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sleep Disorders Center of Alabama | Birmingham | Alabama | 35213 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| Marvel Clinical Research, LLC | Huntington Beach | California | 92647 | — |
| CenExel CNS | Los Alamitos | California | 90720 | — |
| Santa Monica Clinical Trials | Los Angeles | California | 90025 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| SDS Clinical Trials Inc. | Santa Ana | California | 92705 | — |
| Alpine Clinical Research Center | Boulder | Colorado | 80301 | — |
| Mountain View Clinical Research, Inc. | Denver | Colorado | 80209 | — |
| Nuvance Health | Norwalk | Connecticut | 06850 | — |
| Teradan Clinical trials LLC | Brandon | Florida | 33511 | — |
| St. Francis Medical Institute | Clearwater | Florida | 33765 | — |
| Nouvelle Clinical Research | Cutler Bay | Florida | 33189 | — |
| Arrow Clinical Trials | Daytona Beach | Florida | 32117 | — |
| Cenexel Research Centers of America - Hollywood | Hollywood | Florida | 33024 | — |
| Ivetmar Medical Group LLC | Miami | Florida | 33155 | — |
| PharmaDev Clinical Research Institute, LLC | Miami | Florida | 33176 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Palm Beach Research ClinEdge-PPDS | West Palm Beach | Florida | 33409 | — |
| Clinical Site Partners, LLC dba Flourish Research | Winter Park | Florida | 32789 | — |
| NeuroTrials Research | Atlanta | Georgia | 30328 | — |
| CenExel iResearch | Decatur | Georgia | 30030 | — |
| Sleep Practitioners, LLC | Macon | Georgia | 31210 | — |
| Centricity Research Rincon Pulmonology | Rincon | Georgia | 31326 | — |
| Medster Research | Valdosta | Georgia | 31605 | — |
| Chicago Research Center Inc | Chicago | Illinois | 60634 | — |
| Sleep Disorders Centers of the Mid-Atlantic | Glen Burnie | Maryland | 21061 | — |
| Velocity Clinical Research | Rockville | Maryland | 20854 | — |
| Neurocare, Inc | Newton | Massachusetts | 02459 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| Baystate Medical Center (BMC) - Baystate Sleep Medicine | Springfield | Massachusetts | 01199 | — |
| Western Michigan University Homer Stryker M.D. School of Medicine | Kalamazoo | Michigan | 49008 | — |
| Henry Ford Health (Sleep Research Department) | Novi | Michigan | 48377 | — |
| Clinical Neurophysiology Services | Sterling Heights | Michigan | 48314 | — |
| St Lukes Hospital | Chesterfield | Missouri | 63017 | — |
| Healthcare Research Network | Hazelwood | Missouri | 63042 | — |
| Clayton Sleep Institute | St Louis | Missouri | 63123 | — |
| Great Plains Health | North Platte | Nebraska | 69101 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052 | — |
| Clinilabs, Inc | Eatontown | New Jersey | 07724 | — |
| Maimonides Sleep Arts and Sciences | Albuquerque | New Mexico | 87107 | — |
| Northwell Health Physician Partners | New Hyde Park | New York | 11042 | — |
| Research Carolina Elite | Denver | North Carolina | 28037 | — |
| Clinical Research of Gastonia | Gastonia | North Carolina | 28054 | — |
| Advanced Respiratory and Sleep Medicine, LLC | Huntersville | North Carolina | 28078 | — |
| Coastal Carolina Health Care | New Bern | North Carolina | 28562 | — |
| Meridian Clinical Research | Raleigh | North Carolina | 27607 | — |
| NeuroScience Research Center, LLC | Canton | Ohio | 44718 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Sleep Management Institute | Cincinnati | Ohio | 45245 | — |
| Ohio Sleep Medicine Institute | Dublin | Ohio | 43017 | — |
| Northwest Research Center | Portland | Oregon | 97202 | — |
| Brian Abaluck, LLC | Malvern | Pennsylvania | 19355 | — |
| UPMC Comprehensive Lung Center - Sleep Medicine | Pittsburgh | Pennsylvania | 15213 | — |
| Lowcountry Lung and Critical Care | Charleston | South Carolina | 29406 | — |
| Velocity Clinical Research - Greenville | Greenville | South Carolina | 29615 | — |
| Clinical Neuroscience Solutions - Memphis | Memphis | Tennessee | 38119 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| Central Texas Neurology Consultants, PA | Round Rock | Texas | 78681 | — |
| Sleep Therapy Research Center | San Antonio | Texas | 78229 | — |
| Sleep Disorders Centers of the Mid-Atlantic | Vienna | Virginia | 22182 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05811247, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 21, 2025 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05811247 live on ClinicalTrials.gov.