A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT05811351. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b, Randomized, Double-masked, Multicenter, Dose-ranging, Sham-controlled Clinical Trial to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate change in geographic atrophy (GA) lesion growth of eyes treated with JNJ-81201887 compared to sham control.
Study identification
- NCT ID
- NCT05811351
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 305 participants
Conditions and interventions
Conditions
Interventions
- JNJ-81201887 Drug
- Prednisone Drug
- Placebo Other
- Triamcinolone Drug
- Sham Procedure Other
Drug · Other
Eligibility (public fields only)
- Age range
- 60 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 6, 2023 (Actual)
- Primary completion
- Feb 23, 2026 (Actual)
- Completion
- Feb 23, 2026 (Actual)
- Last update posted
- Mar 13, 2026
2023 – 2026
United States locations
- U.S. sites
- 79
- U.S. states
- 26
- U.S. cities
- 69
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Retinal Research Institute | Phoenix | Arizona | 85053 | — |
| Retina Associates Southwest PC | Tucson | Arizona | 85704 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Retina Associates Of Southern California | Huntington Beach | California | 92647 | — |
| Shiley Eye Institute Jacobs Retina Center | La Jolla | California | 92093 0946 | — |
| Jules Stein Eye Institute UCLA | Los Angeles | California | 90095 | — |
| The Retina Partners | Los Angeles | California | 91436 | — |
| California Retina Consultants | Oxnard | California | 93036 | — |
| Stanford Health Care | Palo Alto | California | 94303 | — |
| California Eye Medical Specialists | Pasadena | California | 91107 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retina Consultants of Southern California | Redlands | California | 92374 | — |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | — |
| Colorado Retina - Lakewood Clinic | Lakewood | Colorado | 80228 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| National Opthalmic Research Institute | Fort Myers | Florida | 33912 | — |
| VitreoRetinal Associates, PA | Gainesville | Florida | 32607 | — |
| MedEye Associates | Miami | Florida | 33143 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Fort Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| East Florida Eye Institute | Stuart | Florida | 34994 | — |
| Georgia Retina | Marietta | Georgia | 30060 | — |
| Marietta Eye Clinic | Marietta | Georgia | 30060 | — |
| University Of Illinois | Chicago | Illinois | 60612 | — |
| Retina Associates | Elmhurst | Illinois | 60126 | — |
| University Retina | Lemont | Illinois | 60439 | — |
| Midwest Eye Institute | Carmel | Indiana | 46032 | — |
| Maine Eye Center | Portland | Maine | 04101 | — |
| Retina Specialists | Baltimore | Maryland | 21204 | — |
| The Retina Care Center | Baltimore | Maryland | 21209 | — |
| The Retina Group of Washington | Chevy Chase | Maryland | 20815 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| Vitreo Retinal Associates-Worcester | Worcester | Massachusetts | 01605 | — |
| Foundation for Vision Research | Grand Rapids | Michigan | 49546 | — |
| Associated Retinal Consultants P.C. | Royal Oak | Michigan | 48073 | — |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | — |
| The Retina Institute | St Louis | Missouri | 63144 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Wills Eye/Mid Atlantic Retina | Cherry Hill | New Jersey | 08034 | — |
| Long Island Vitreo Retinal Consultants | Great Neck | New York | 11021 | — |
| Retina-Vitreous Surgeons of Central New York | Liverpool | New York | 13088 | — |
| Vitreous Retina Macula Consultants of New York | New York | New York | 10022 | — |
| Retina Consultants PLLC | Slingerlands | New York | 12159 | — |
| Opthalmic Consultants of the Capital Region | Troy | New York | 12180 | — |
| Asheville Eye Associates - Western Carolina Retinal Associates | Asheville | North Carolina | 28803 | — |
| Duke University | Durham | North Carolina | 27705-4699 | — |
| Graystone Eye | Hickory | North Carolina | 28602 | — |
| NC Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| Verum Research LLC | Eugene | Oregon | 97401 | — |
| Casey Eye Institute | Portland | Oregon | 97239 | — |
| Cascade Medical Research Institute, LLC | Springfield | Oregon | 97477 | — |
| Erie Retina Research | Erie | Pennsylvania | 16505 | — |
| Charleston Neuroscience Institute, LLC | Beaufort | South Carolina | 29902 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Panhandle Eye Group LLP-Southwest Retina Specialists | Amarillo | Texas | 79106 | — |
| Austin Clinical Research | Austin | Texas | 78750 | — |
| Retina and Vitreous of Texas, PLLC | Bellaire | Texas | 77401 | — |
| Retina Consultants of Texas 2 | Bellaire | Texas | 77401 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| UT Southwestern | Dallas | Texas | 75390 | — |
| Texas Retina Associates 1 | Fort Worth | Texas | 76104 | — |
| Houston Eye Associates | Houston | Texas | 77025 | — |
| San Antonio Eye Center | San Antonio | Texas | 78215 | — |
| Retina Associates Of South Texas P A | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group | Willow Park | Texas | 76087 | — |
| Retina Associates of Utah P C | Salt Lake City | Utah | 84107 | — |
| Rocky Mountain Retina Consultants | Salt Lake City | Utah | 84107 | — |
| University of Utah | Salt Lake City | Utah | 84132 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
| Wagner Kapoor Research institute | Norfolk | Virginia | 23502 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 83 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05811351, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 13, 2026 · Synced Oct 18, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05811351 live on ClinicalTrials.gov.