Parallel-Arm Study to Compare AD109 to Placebo With Patients With OSA (SynAIRgy Study)
Public ClinicalTrials.gov record NCT05813275. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of Aroxybutynin/Atomoxetine (AD109) to Placebo in Obstructive Sleep Apnea (SynAIRgy Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 3 Randomized Double-Blind Placebo-Controlled 6-month Parallel-Arm Study to Compare a Fixed Dose Combination of AD109 to Placebo in Obstructive Sleep Apnea.
Study identification
- NCT ID
- NCT05813275
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 646 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 16, 2023 (Actual)
- Primary completion
- Mar 10, 2025 (Actual)
- Completion
- Mar 14, 2025 (Actual)
- Last update posted
- Sep 11, 2026
2023 – 2025
United States locations
- U.S. sites
- 65
- U.S. states
- 23
- U.S. cities
- 59
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alabama Neurology & Sleep Medicine | Tuscaloosa | Alabama | 35406 | — |
| Desert Clinical Research - CCT Research | Mesa | Arizona | 85213 | — |
| Foothills Research Center - CCT Research | Phoenix | Arizona | 85044 | — |
| Fiel Family Sports Medicine - PC CCT Research | Tempe | Arizona | 85283 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Preferred Research Partners, Inc. | Little Rock | Arkansas | 72211 | — |
| Orange County Research Institute | Anaheim | California | 92801 | — |
| North County Neurology Associates | Carlsbad | California | 92011 | — |
| Core Healthcare Group | Cerritos | California | 90703 | — |
| Exalt Clinical Research | Chula Vista | California | 91910 | — |
| Catalina Research Institute | Montclair | California | 91763 | — |
| Probe Clinical Research Corporation | Riverside | California | 92501 | — |
| Pacific Research Network | San Diego | California | 92103 | — |
| Sleep Medicine Specialists of California | San Ramon | California | 94583 | — |
| SDS Clinical Trials Inc. | Santa Ana | California | 92705 | — |
| Provideré Research Inc. | West Covina | California | 91790 | — |
| Meris Clinical Research | Brandon | Florida | 33511 | — |
| Nouvelle Clinical Research | Cutler Bay | Florida | 33189 | — |
| Accel Research Sites | DeLand | Florida | 32720 | — |
| Research Centers of America, LLC | Hollywood | Florida | 33024 | — |
| Canvas Clinical Research | Lake Worth | Florida | 33467 | — |
| Florida Lung and Sleep Associates | Lehigh Acres | Florida | 33971 | — |
| Advanced Medical Research Institute | Miami | Florida | 33174 | — |
| Clinical Site Partners | Miami | Florida | 33186 | — |
| Clinical Neuroscience Solutions, Inc - Orlando | Orlando | Florida | 32801 | — |
| JSV Clinical Research Study Inc | Tampa | Florida | 33634 | — |
| Florida Pediatric Research Institute | Winter Park | Florida | 32789 | — |
| Atlanta Center for Medical Research, LLC | Atlanta | Georgia | 30031 | — |
| NeuroTrials Research | Atlanta | Georgia | 30342 | — |
| Georgia Neurology and Sleep Medicine Assoc | Suwanee | Georgia | 30024 | — |
| Javarra Inc-Privia Medical Group | Thomasville | Georgia | 31792 | — |
| St. Lukes Clinic - Idaho Pulmonary Associates | Meridian | Idaho | 83642 | — |
| Chicago Research Center Inc | Chicago | Illinois | 60634 | — |
| OSF HealthCare Saint Francis Medical Center | Peoria | Illinois | 61637 | — |
| The University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Advanced ENT and Allergy | Louisville | Kentucky | 40220 | — |
| Centennial Medical Group | Elkridge | Maryland | 21075 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Revive Research Institute | Lathrup Village | Michigan | 48076 | — |
| Las Vegas Clinical Trials | North Las Vegas | Nevada | 89030 | — |
| Neurology Specialists of Monmouth County | West Long Branch | New Jersey | 07764 | — |
| Javara Inc - Tryon Medical Partners PLCC | Charlotte | North Carolina | 28210 | — |
| Research Carolina Elite | Denver | North Carolina | 28025 | — |
| Peters Medical Research, LLC | High Point | North Carolina | 27260 | — |
| PMG Research of Wilmington | Wilmington | North Carolina | 28401 | — |
| Lillestol Research LLC | Fargo | North Dakota | 58104 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Sleep Management Institute (Intrepid) | Cincinnati | Ohio | 45245 | — |
| UC Health Sleep Medicine | Cincinnati | Ohio | 45267 | — |
| University Hospital of Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Abington Neurological Associate | Abington | Pennsylvania | 19001 | — |
| Respiratory Specialists | Wyomissing | Pennsylvania | 19610 | — |
| Tribe Clinical Research LL | Greenville | South Carolina | 29607 | — |
| OnSite Clinical Solutions LLC/Carolina Cardiology Associates P.A | Rock Hill | South Carolina | 29732 | — |
| Chattanooga Research & Medicine, PLLC | Chattanooga | Tennessee | 37404 | — |
| FutureSearch Trials of Neurology | Austin | Texas | 78731 | — |
| FutureSearch Trials of Dallas, LP | Dallas | Texas | 75231 | — |
| The Heights Hospital (HD Heights) | Houston | Texas | 77008 | — |
| Weill Cornell Medical College | Houston | Texas | 77030 | — |
| Lone Star Lung and Sleep Clinic | Houston | Texas | 77070 | — |
| Huntsville Research Institute LLC | Huntsville | Texas | 77340 | — |
| Epic Medical Research | Red Oak | Texas | 75154 | — |
| Element Research Group | San Antonio | Texas | 78229 | — |
| South Ogden Family Medicine / CCT Research | South Ogden | Utah | 84405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05813275, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 11, 2026 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05813275 live on ClinicalTrials.gov.