A Study to Assess the Effect of Dexpramipexole in Adolescents and Adults With Severe Eosinophilic Asthma (EXHALE-3)
Public ClinicalTrials.gov record NCT05813288. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 52 Weeks in Participants With Severe Eosinophilic Asthma
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The objective of this clinical study is to investigate the safety, tolerability, and efficacy of dexpramipexole in participants with inadequately controlled severe eosinophilic asthma.
Study identification
- NCT ID
- NCT05813288
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 654 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 12 Years to 99 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 27, 2023 (Actual)
- Primary completion
- Dec 8, 2025 (Actual)
- Completion
- Dec 8, 2025 (Actual)
- Last update posted
- Dec 15, 2025
2023 – 2025
United States locations
- U.S. sites
- 76
- U.S. states
- 21
- U.S. cities
- 67
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Site 30001-287 | Mobile | Alabama | 36608 | — |
| Research Site 30001-487 | Chandler | Arizona | 85224 | — |
| Research Site 30001-462 | Peoria | Arizona | 85381 | — |
| Research Site 30001-322 | Surprise | Arizona | 85378 | — |
| Research Site 30001-458 | Tucson | Arizona | 85724 | — |
| Research Site 30001-010 | Little Rock | Arkansas | 72212 | — |
| Research Site 30001-502 | Canoga Park | California | 91303 | — |
| Research Site 30001-485 | Inglewood | California | 96410 | — |
| Research Site 30001-362 | Laguna Niguel | California | 92677 | — |
| Research Site 30001-497 | Los Angeles | California | 90017 | — |
| Research Site 30001-500 | Northridge | California | 91324 | — |
| Research Site 30001-489 | Pasadena | California | 91105 | — |
| Research Site 30001-501 | San Diego | California | 92120 | — |
| Research Site 30001-434 | San Diego | California | 92123 | — |
| Research Site 30001-484 | Santa Monica | California | 90424 | — |
| Research Site 30001-304 | Valencia | California | 91355 | — |
| Research Site 30001-305 | Valencia | California | 97355 | — |
| Research Site 30001-291 | Jacksonville | Florida | 32216 | — |
| Research Site 30001-318 | Maitland | Florida | 32751 | — |
| Research Site 30001-311 | Miami | Florida | 33144 | — |
| Research Site 30001-288 | Miami | Florida | 33165 | — |
| Research Site 30001-310 | Miami | Florida | 33165 | — |
| Research Site 30001-329 | Miami | Florida | 33165 | — |
| Research Site 30001-082 | Miami | Florida | 33179 | — |
| Research Site 30001-301 | Naples | Florida | 34103 | — |
| Research Site 30001-348 | Ocala | Florida | 34471 | — |
| Research Site 30001-331 | Orlando | Florida | 32807 | — |
| Research Site 30001-293 | Orlando | Florida | 32819 | — |
| Research Site 30001-312 | Pembroke Pines | Florida | 33026 | — |
| Research Site 30001-429 | Plantation | Florida | 33317 | — |
| Research Site 30001-319 | Viera | Florida | 32940 | — |
| Research Site 30001-452 | Dunwoody | Georgia | 30350 | — |
| Research Site 30001-483 | East Point | Georgia | 30344 | — |
| Research Site 30001-366 | Lilburn | Georgia | 30047 | — |
| Research Site 30001-328 | Maywood | Illinois | 60153 | — |
| Research Site 30001-535 | Westchester | Illinois | 60154 | — |
| Research Site 30001-347 | Louisville | Kentucky | 40202 | — |
| Research Site 30001-437 | Alexandria | Louisiana | 71303 | — |
| Research Site 30001-286 | Lafayette | Louisiana | 70508 | — |
| Research Site 30001-313 | Marrero | Louisiana | 70072 | — |
| Research Site 30001-352 | Zachary | Louisiana | 70791 | — |
| Research Site 30001-414 | Annapolis | Maryland | 37067 | — |
| Research Site 30001-472 | Farmington Hills | Michigan | 48336 | — |
| Research Site 30001-442 | Southfield | Michigan | 48034 | — |
| Research Site 30001-372 | Warren | Michigan | 48088 | — |
| Research Site 30001-421 | Mankato | Minnesota | 56001 | — |
| Research Site 30001-406 | Rochester | Minnesota | 55905 | — |
| Research Site 30001-522 | North Las Vegas | Nevada | 89030 | — |
| Research Site 30001-363 | Edison | New Jersey | 08817 | — |
| Research Site 30001-499 | Hamilton | New Jersey | 08619 | — |
| Research Site 30001-474 | Massena | New York | 13662 | — |
| Research Site 30001-455 | New York | New York | 10016 | — |
| Research Site US-30001-369 | New York | New York | 10029 | — |
| Research Site 30001-300 | Schenectady | New York | 12304 | — |
| Research Site 30001-398 | Charlotte | North Carolina | 28277 | — |
| Research Site 30001-439 | Rocky Mount | North Carolina | 27804 | — |
| Research Site 30001-413 | Cleveland | Ohio | 44106 | — |
| Research Site 30001-495 | Columbus | Ohio | 43235 | — |
| Research Site 30001-327 | Philadelphia | Pennsylvania | 19140 | — |
| Research Site 30001-414 | Franklin | Tennessee | 37067 | — |
| Research Site 30001-364 | Memphis | Tennessee | 38105 | — |
| Research Site 30001-334 | Allen | Texas | 60607 | — |
| Research Site 30001-090 | Austin | Texas | 78726 | — |
| Research Site 30001-415 | Dallas | Texas | 75246 | — |
| Research Site US-30001-418 | Frisco | Texas | 75034 | — |
| Research Site 30001-299 | Houston | Texas | 77063 | — |
| Research Site 30001-315 | Katy | Texas | 77494 | — |
| Research Site 30001-295 | McKinney | Texas | 75069 | — |
| Research Site 30001-373 | Mesquite | Texas | 75150 | — |
| Research Site 30001-481 | Nederland | Texas | 71627 | — |
| Research Site 30001-297 | Pearland | Texas | 77584 | — |
| Research Site 30001-238 | San Antonio | Texas | 78258 | — |
| Research Site 30001-377 | San Antonio | Texas | 78258 | — |
| Research Site 30001-335 | Sugar Land | Texas | 77479 | — |
| Research Site 30001-333 | Pleasant View | Utah | 84404 | — |
| Research Site 30001-515 | West Valley City | Utah | 84120 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 206 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05813288, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 15, 2025 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05813288 live on ClinicalTrials.gov.