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Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

A Study to Assess the Safety and Immune Response of a Vaccine Against Influenza in Healthy Younger and Older Adults

ClinicalTrials.gov ID: NCT05823974

Public ClinicalTrials.gov record NCT05823974. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jul 24, 2026, 12:34 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/2, Randomized, Dose-finding/Dose-confirmation Study to Evaluate the Reactogenicity, Safety and Immunogenicity of mRNA-based Multivalent Seasonal Influenza Vaccine Candidates Administered in Healthy Younger and Older Adults

Study identification

NCT ID
NCT05823974
Recruitment status
Completed
Study type
Interventional
Phase
Phase 1, Phase 2
Lead sponsor
GlaxoSmithKline
Industry
Enrollment
1,275 participants

Conditions and interventions

Interventions

  • F2C22C/DL001Z Biological
  • F2B22A/DL001Z Biological
  • F2B22B/DL001Z Biological
  • F2B22C/DL001Z Biological
  • F2B22D/DL001Z Biological
  • F2B22E/DL001Z Biological
  • F2F22A/DL001Z Biological
  • F2F22B/DL001Z Biological
  • F2F22C/DL001Z Biological
  • F2F22D/DL001Z Biological
  • F2F22E/DL001Z Biological
  • Control 1 Combination Product
  • F2F23D/DL001Z-NH Biological
  • F2F23A/DL001Z-NH Biological
  • F2F23B/DL001Z-NH Biological
  • Control 2 Combination Product
  • F2F23C/DL001Z-NH Biological
  • Control 3 Combination Product
  • F2F22F/DL001Z Biological

Biological · Combination Product

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 26, 2023
Primary completion
Jul 1, 2024
Completion
Dec 17, 2024
Last update posted
Jul 22, 2025

2023 – 2024

United States locations

U.S. sites
24
U.S. states
15
U.S. cities
24
Facility City State ZIP Site status
GSK Investigational Site Hialeah Florida 33012
GSK Investigational Site Miami Florida 33186
GSK Investigational Site Chicago Illinois 60640
GSK Investigational Site Valparaiso Indiana 46383
GSK Investigational Site Lenexa Kansas 66219
GSK Investigational Site Wichita Kansas 67207
GSK Investigational Site Lexington Kentucky 40509
GSK Investigational Site Boston Massachusetts 02215
GSK Investigational Site Dearborn Michigan 48127
GSK Investigational Site Papillion Nebraska 68046
GSK Investigational Site Rochester New York 14609
GSK Investigational Site Syracuse New York 13057
GSK Investigational Site Denver North Carolina 80110
GSK Investigational Site Greensboro North Carolina 27408
GSK Investigational Site Raleigh North Carolina 27612
GSK Investigational Site Wilmington North Carolina 28401
GSK Investigational Site Dayton Ohio 33147
GSK Investigational Site East Greenwich Rhode Island 02818
GSK Investigational Site Knoxville Tennessee 37909
GSK Investigational Site Fort Worth Texas 76135
GSK Investigational Site Houston Texas 48076
GSK Investigational Site Tomball Texas 77375
GSK Investigational Site Newport News Virginia 23606
GSK Investigational Site Norfolk Virginia 23502

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 17 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05823974, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 22, 2025 · Synced Jul 24, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05823974 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →