A Study to Compare Iberdomide Maintenance Versus Lenalidomide Maintenance Therapy Following Autologous Stem Cell Transplant in Participants With Newly Diagnosed Multiple Myeloma
Public ClinicalTrials.gov record NCT05827016. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Two-stage, Randomized, Multi-center, Controlled, Open-label Study Comparing Iberdomide Maintenance to Lenalidomide Maintenance Therapy After Autologous Stem Cell Transplantation (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (NDMM) (EXCALIBER-Maintenance)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to compare the effectiveness of iberdomide maintenance to lenalidomide maintenance therapy after autologous stem cell transplantation (ASCT) in participants with newly diagnosed multiple myeloma (NDMM).
Study identification
- NCT ID
- NCT05827016
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,230 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 22, 2023 (Actual)
- Primary completion
- Mar 15, 2029 (Estimated)
- Completion
- Jan 1, 2036 (Estimated)
- Last update posted
- Sep 17, 2026
2023 – 2036
United States locations
- U.S. sites
- 44
- U.S. states
- 18
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Local Institution - 0202 | Aurora | Colorado | 80012-5405 | — |
| Local Institution - 0007 | Jacksonville | Florida | 32224-1865 | — |
| Local Institution - 0308 | Tampa | Florida | 33606 | — |
| Local Institution - 0192 | Tampa | Florida | 33612-9416 | — |
| Local Institution - 0003 | Weston | Florida | 33331-3609 | — |
| Local Institution - 0019 | Athens | Georgia | 30607-1465 | — |
| Local Institution - 0018 | Atlanta | Georgia | 30322-1013 | — |
| Local Institution - 0021 | Augusta | Georgia | 30912 | — |
| Local Institution - 0237 | Chicago | Illinois | 60637-1426 | — |
| University of Kansas Cancer Center - The Richard and Annette Bloch Cancer Care Pavilion | Westwood | Kansas | 66205-2003 | — |
| Local Institution - 0205 | Clinton | Maryland | 20735-4230 | — |
| Local Institution - 0279 | Worcester | Massachusetts | 01655 | — |
| Local Institution - 0001 | Ann Arbor | Michigan | 48109-5000 | — |
| Local Institution - 0257 | Detroit | Michigan | 48202-2610 | — |
| Local Institution - 0296 | Grand Rapids | Michigan | 49503 | — |
| Local Institution - 0303 | Rochester | Minnesota | 55905 | — |
| Local Institution - 0207 | Hattiesburg | Mississippi | 39401 | — |
| Local Institution - 0191 | Morristown | New Jersey | 07960 | — |
| Local Institution - 0328 | Brooklyn | New York | 11220-3313 | — |
| Local Institution - 0288 | Mineola | New York | 11501 | — |
| Local Institution - 0180 | New York | New York | 10016-6402 | — |
| Local Institution - 0020 | New York | New York | 10032-3729 | — |
| Local Institution - 0274 | Westbury | New York | 11590-5119 | — |
| Local Institution - 0331 | Charlotte | North Carolina | 28204 | — |
| Local Institution - 0005 | Charlotte | North Carolina | 28803-2493 | — |
| Local Institution - 0281 | Durham | North Carolina | 27705-3976 | — |
| Local Institution - 0286 | Winston-Salem | North Carolina | 27103 | — |
| Local Institution - 0322 | Winston-Salem | North Carolina | 27157 | — |
| Local Institution - 0238 | Cincinnati | Ohio | 45236-2725 | — |
| Local Institution - 0299 | Cleveland | Ohio | 44111 | — |
| Local Institution - 0002 | Cleveland | Ohio | 44195 | — |
| Local Institution - 0017 | Kansas | Ohio | 64132 | — |
| Local Institution - 0301 | Mayfield Heights | Ohio | 44124 | — |
| Local Institution - 0013 | Toledo | Ohio | 43623 | — |
| Local Institution - 0300 | Wooster | Ohio | 44691 | — |
| Local Institution - 0203 | Eugene | Oregon | 97401 | — |
| Local Institution - 0012 | Philadelphia | Pennsylvania | 19107 | — |
| Local Institution - 0011 | Philadelphia | Pennsylvania | 19111-2433 | — |
| Local Institution - 0253 | Pittsburgh | Pennsylvania | 15232 | — |
| Local Institution - 0294 | Germantown | Tennessee | 38138-1762 | — |
| Local Institution - 0004 | Nashville | Tennessee | 37203-1625 | — |
| Local Institution - 0193 | Dallas | Texas | 75246 | — |
| Local Institution - 0009 | Dallas | Texas | 75390-0001 | — |
| Local Institution - 0006 | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 225 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05827016, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 17, 2026 · Synced Oct 3, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05827016 live on ClinicalTrials.gov.